Title:
FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/062876
Kind Code:
A1
Abstract:
Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence label of proteins, and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.
Inventors:
ZHU LINYONG (CN)
YANG YI (CN)
BAO BINGKUN (CN)
ZHANG CHENXIA (CN)
ZHANG DASHENG (CN)
BAO CHUNYAN (CN)
LIN QIUNING (CN)
LI NINGFENG (CN)
HUA XIN (CN)
ZHAO YONGLIANG (CN)
LIU RENMEI (CN)
CHEN ZHENGDA (CN)
SUN YUYING (CN)
YANG YI (CN)
BAO BINGKUN (CN)
ZHANG CHENXIA (CN)
ZHANG DASHENG (CN)
BAO CHUNYAN (CN)
LIN QIUNING (CN)
LI NINGFENG (CN)
HUA XIN (CN)
ZHAO YONGLIANG (CN)
LIU RENMEI (CN)
CHEN ZHENGDA (CN)
SUN YUYING (CN)
Application Number:
PCT/CN2018/108519
Publication Date:
April 04, 2019
Filing Date:
September 29, 2018
Export Citation:
Assignee:
UNIV EAST CHINA SCIENCE & TECH (CN)
International Classes:
C07D209/24; C09K11/06; C07D239/49; C07D311/16; C07D311/82; C07D403/14; C07D405/12; C07D405/14; C07D409/14; C07D487/04; G01N21/64
Domestic Patent References:
| WO2004031405A1 | 2004-04-15 | |||
| WO2008012296A1 | 2008-01-31 | |||
| WO2004072232A2 | 2004-08-26 | |||
| WO2013142841A1 | 2013-09-26 |
Foreign References:
| CN104745177A | 2015-07-01 | |||
| CN102127059A | 2011-07-20 | |||
| CN103666456A | 2014-03-26 |
Other References:
T. KOMATSU., J. AM. CHEM. SOC., vol. 133, 2011, pages 6745 - 6751
TK LIU., ACS CHEM. BIOL., vol. 9, 2014, pages 2359 - 2365
TY WANG, CHEM SCI., vol. 7, 2016, pages 301 - 307
J. DAS, BIOORG. MED. CHEM. LETT., vol. 15, 2005, pages 337 - 343
L. X. WUK. BURGESS, J. AM. CHEM. SOC., vol. 130, 2008, pages 4089 - 4096
WANG H. ET AL., TETRA LET., vol. 48, 2007, pages 3471 - 3474
MYUNG KIM ET AL., ANAL CHEM., vol. 86, 2014, pages 308 - 311
GEN-ICHI KONISHI, TETRAHEDRON, vol. 70, 2014, pages 7551 - 7559
GAMBA-SÁNCHEZ, TETRAHEDRON LETT., vol. 56, 2015, pages 4308 - 4311
SIMON J. A. POPE, CHEM. COMMUN., 2009, pages 4278 - 4280
GUIDO GAIETTA ET AL., SCIENCE, vol. 296, 2002, pages 503 - 507
See also references of EP 3690002A4
TK LIU., ACS CHEM. BIOL., vol. 9, 2014, pages 2359 - 2365
TY WANG, CHEM SCI., vol. 7, 2016, pages 301 - 307
J. DAS, BIOORG. MED. CHEM. LETT., vol. 15, 2005, pages 337 - 343
L. X. WUK. BURGESS, J. AM. CHEM. SOC., vol. 130, 2008, pages 4089 - 4096
WANG H. ET AL., TETRA LET., vol. 48, 2007, pages 3471 - 3474
MYUNG KIM ET AL., ANAL CHEM., vol. 86, 2014, pages 308 - 311
GEN-ICHI KONISHI, TETRAHEDRON, vol. 70, 2014, pages 7551 - 7559
GAMBA-SÁNCHEZ, TETRAHEDRON LETT., vol. 56, 2015, pages 4308 - 4311
SIMON J. A. POPE, CHEM. COMMUN., 2009, pages 4278 - 4280
GUIDO GAIETTA ET AL., SCIENCE, vol. 296, 2002, pages 503 - 507
See also references of EP 3690002A4
Attorney, Agent or Firm:
SHANGHAI ESSEN PATENT & TRADEMARK OFFICE (CN)
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