Title:
FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS
Document Type and Number:
WIPO Patent Application WO2002100802
Kind Code:
A3
Abstract:
A method of reacting a first compound to produce a second compound includes the step of contacting a first non-fluorous phase including the first compound with a first fluorous phase at a first phase interface. The first compound distributes between the first fluorous phase and the first non-fluorous phase. The method further includes the steps of contacting the first fluorous phase with a second non-fluorous phase at a second phase interface and including at least a third compound in the second non-fluorous phase that reacts with the first compound to produce the second compound. The second compound has a distribution coefficient less than the first compound. This method can, for example be used to separate the second compound from unreacted first compound wherein, for example, the first compound is of a fluorous nature and distributes more readily into (or transports more quickly through) the fluorous phase than does the second compound. In general, the fluorous phase serves as a barrier to prevent the two non-fluorous phases from mixing, but molecules that can migrate through the fluorous phase can pass from one side to the other.
Inventors:
CURRAN DENNIS P
WEBER STEPHEN G
NAKAMURA HIROYUKI
LINCLAU BRUNO
SUN LIFANG
RYU ILHYONG
MATSUBARA HIROSHI
WEBER STEPHEN G
NAKAMURA HIROYUKI
LINCLAU BRUNO
SUN LIFANG
RYU ILHYONG
MATSUBARA HIROSHI
Application Number:
PCT/US2002/017829
Publication Date:
December 11, 2003
Filing Date:
June 05, 2002
Export Citation:
Assignee:
UNIV PITTSBURGH (US)
International Classes:
C07B37/04; C07B39/00; C07B41/02; C07B41/06; C07B61/00; C07B63/00; C07C1/32; C07C17/02; C07C23/10; C07C29/00; C07C33/46; C07C45/46; C07C49/84; C07D207/333; C07D307/46; C07D333/22; C07D207/32; (IPC1-7): C07F7/00; C07D333/76
Foreign References:
| US5777121A | 1998-07-07 | |||
| US5463082A | 1995-10-31 |
Other References:
See also references of EP 1404687A4
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