Title:
FOOD INTAKE SUPPRESSANT AND ANTI-OBESITY AGENT
Document Type and Number:
WIPO Patent Application WO/2012/086811
Kind Code:
A1
Abstract:
The present invention provides a food intake suppressant and an anti-obesity agent containing the compounds represented by formula (I''). (In the formula, at least one of R11, R12, R13, R14 and R15 is a G-O- group (where G represents a sugar moiety), while the others represent, independently, a hydrogen atom, a hydroxyl group, C1-6 alkyl, C1-6 alkoxy, C1-6 alkyl-carbonyloxy, or a G-O- group; X1 represents a single bond, or a methylene group, an ethylene group, a trimethylene group, or a vinylene group; X2 represents -CO-O-, or -O-CO-; p and q each represent an integer from 0 to 7 so as to satisfy a relationship of p + q = 2 to 8; Y1 represents a methylene group, an ethylene group, or an alkenyl group with 2 to 15 carbons containing 1 to 3 double bonds (where the double bonds may be either cis or trans isomers); and R16 and R17 represent, independently, a hydrogen atom, a methyl group, or an ethyl group.)
Inventors:
KUROSAWA WATARU (JP)
NOMURA KENZO (JP)
AMINO YUSUKE (JP)
NOGUSA YOSHIHITO (JP)
OYAMA KANA (JP)
NOMURA KENZO (JP)
AMINO YUSUKE (JP)
NOGUSA YOSHIHITO (JP)
OYAMA KANA (JP)
Application Number:
PCT/JP2011/079932
Publication Date:
June 28, 2012
Filing Date:
December 22, 2011
Export Citation:
Assignee:
AJINOMOTO KK (JP)
KUROSAWA WATARU (JP)
NOMURA KENZO (JP)
AMINO YUSUKE (JP)
NOGUSA YOSHIHITO (JP)
OYAMA KANA (JP)
KUROSAWA WATARU (JP)
NOMURA KENZO (JP)
AMINO YUSUKE (JP)
NOGUSA YOSHIHITO (JP)
OYAMA KANA (JP)
International Classes:
C07H15/203; A23L33/00; A61K31/7034; A61P3/04
Foreign References:
| JPH1171225A | 1999-03-16 | |||
| JPH07173046A | 1995-07-11 | |||
| EP0597776A1 | 1994-05-18 | |||
| US20030153030A1 | 2003-08-14 | |||
| JPH08268858A | 1996-10-15 | |||
| JPH08268869A | 1996-10-15 | |||
| JPH08268870A | 1996-10-15 | |||
| JPH08268868A | 1996-10-15 |
Other References:
KOTO S. ET AL.: "alpha-Glucosylation of phenols with tetra-O-benzyl-alpha-D-glucose", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 54, no. 6, 1981, pages 1895 - 1896, XP055118286
WU X. ET AL.: "Chemical constituents of Lavandula angustifolia", HUAXUE XUEBAO, vol. 65, no. 16, 2007, pages 1649 - 1653, XP008169518
YANG L. ET AL.: "High-performance liquid chromatography-diode array detection/electrospray ionization mass spectrometry for the simultaneous analysis of cis-, trans- and dihydro- 2-glucosyloxycinnamic acid derivatives from Dendrobium medicinal plants", RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 21, no. 12, 2007, pages 1833 - 1840
MORIKAWA T. ET AL.: "Bioactive constituents from chinese natural medicines. XIV. New glycosides of betha-carboline-type alkaloid, neolignan, and phenylpropanoid from Stellaria dichotoma L. var. lanceolata and their antiallergic activities", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 52, no. 10, 2004, pages 1194 - 1199
WU X. ET AL.: "Chemical constituents of Lavandula angustifolia", HUAXUE XUEBAO, vol. 65, no. 16, 2007, pages 1649 - 1653, XP008169518
YANG L. ET AL.: "High-performance liquid chromatography-diode array detection/electrospray ionization mass spectrometry for the simultaneous analysis of cis-, trans- and dihydro- 2-glucosyloxycinnamic acid derivatives from Dendrobium medicinal plants", RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 21, no. 12, 2007, pages 1833 - 1840
MORIKAWA T. ET AL.: "Bioactive constituents from chinese natural medicines. XIV. New glycosides of betha-carboline-type alkaloid, neolignan, and phenylpropanoid from Stellaria dichotoma L. var. lanceolata and their antiallergic activities", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 52, no. 10, 2004, pages 1194 - 1199
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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