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Title:
FORMULATIONS CONTAINING ANTI-TIGIT ANTIBODY AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/083074
Kind Code:
A1
Abstract:
Provided are the pharmaceutical formulations of antibodies against T cell immunoreceptor with Ig and ITIM domains (TIGIT), or antigen binding fragments thereof. The pharmaceutical formulations exhibit a substantial degree of anti-TIGIT antibody stability after being subjected to stress conditions, accelerated and long-term storage. Also provided are methods of making and methods of using such antibody formulations.

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Inventors:
JIN XIAOQING (CN)
GU SUFANG (CN)
JI YU (CN)
SHEN JIAN (CN)
XU KAI (CN)
LI JINMEI (CN)
WU JUN (CN)
ZHANG YUANYUAN (CN)
DI AIJUN (CN)
QIU BO (CN)
Application Number:
PCT/CN2023/124732
Publication Date:
April 25, 2024
Filing Date:
October 16, 2023
Export Citation:
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Assignee:
BEIGENE LTD (GB)
JIN XIAOQING (CN)
International Classes:
A61K39/395
Domestic Patent References:
WO2021227940A12021-11-18
Foreign References:
CN115023442A2022-09-06
CN102770157A2012-11-07
CN111526888A2020-08-11
CN114641502A2022-06-17
CN113713094A2021-11-30
CN115052893A2022-09-13
CN110818795A2020-02-21
CN111836831A2020-10-27
CN107815467A2018-03-20
CN111718415A2020-09-29
CN114555116A2022-05-27
CN114650999A2022-06-21
CN115066431A2022-09-16
US20210395366A12021-12-23
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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