Description

The present invention relates to fungicidal compositions comprising

I) mefentrifluconazole and

II) one or more of the following compounds:

11.1 (Z)-N-allyloxy-1-(2,4-dichlorophenyl)-2-imidazol-1-yl-ethani mine;

11.2 3-chloro-4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine ;

11.3 N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamid ine;

11.4 methyl (E)-2-[2-[(5-cyano-2-methyl-phenoxy)methyl]phenyl]-3-methoxy -prop-2- enoate;

11.5 methyl (E)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-3-methoxy-prop -2- enoate;

11.6 N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]butanamide;

11.7 N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfa nyl-acetamide;

11.8 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)buta namide;

11.9 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)-2-m ethoxy-acetamide;

11.10 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-propyl-butanamide;

11.1 1 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methoxy-N-propyl-ac etamide;

11.12 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfanyl-N-pr opyl-acetamide;

11.13 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)-2-m ethylsulfanyl- acetamide;

11.14 N'-(5-bromo-6-indan-2-yloxy-2-methyl-3-pyridyl)-N-ethyl-N-me thyl-formamidine;

11.15 N'-[5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methyl-3-pyri dyl]-N-ethyl-N- methyl-formamidine;

11.16 N'-[5-bromo-6-(4-isopropylcyclohexoxy)-2-methyl-3-pyridyl]-N -ethyl-N-methyl- formamidine;

11.17 N'-[5-bromo-2-methyl-6-(1 -phenylethoxy)-3-pyridyl]-N-ethyl-N-methyl- formamidine including agriculturally acceptable salts thereof.

The invention also relates to a use of a composition according to the present invention for con- trolling phytopathogenic fungi.

Moreover, the invention relates to a method for controlling phytopathogenic harmful fungi, using the inventive compositions and to the use of mefentrifluconazole with one or more compound of component II) for preparing such compositions. In such a method, the fungi, their habitat, their locus or the plants to be protected against fungal attack, the soil or plant propagation material are treated with an effective amount of a composition according to the present invention.

Further, the invention relates to a method for improving the health of plants, wherein the plants, the locus where the plants are growing or are expected to grow, or plant propagation material from which the plants grow, are treated with an effective amount of a composition according to the present invention.

The term "fungicidally effective amount" denotes an amount of the composition or of the com- ponents of the composition, which is sufficient for controlling harmful fungi on cultivated plants or in the protection of stored products or harvest or of materials and which does not result in a substantial damage to the treated plants, the treated stored products or harvest, or to the treat- ed materials. Such an amount can vary in a broad range and is dependent on various factors, such as the fungal species to be controlled, the treated cultivated plant, stored product, harvest or material, the climatic conditions, desired pesticidal effect and duration, locus, mode of appli cation, and the like.

"Locus" means a plant, plant propagation material (preferably seed), soil, area, material or envi- ronment in which a pest is growing or may grow.

Additionally, the invention relates to a method for protection of plant propagation material, pref- erably seeds, from pytopathogenic fungi, comprising contacting the plant propagation materials with a composition according to the present invention.

The term "plant propagation material" is to be understood to denote all the generative parts of the plant, such as seeds; and vegetative plant materials, such as cuttings and tubers (e. g. pota- toes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants; including seedlings and young plants, which are to be transplanted after germination or after emergence from soil.

These young plants may also be protected before transplantation by a total or partial treatment by immersion or pouring. In a particularly preferred embodiment, the term propagation material denotes seeds.

Preferably, treatment of plant propagation materials with compositions according to the present invention is used for controlling a multitude of fungi on cereals, such as wheat, rye, barley and oats; rice, corn, cotton and soybeans.

Mefentrifluconazole, its fungicidal activity and compositions are known from e.g. WO

2013/007767 and WO 2014/095994. Owing to the basic character of its nitrogen atoms, mefen- trifluconazole is capable of forming salts or adducts with inorganic or organic acids or with metal ions, in particular salts with inorganic acids.

Agriculturally acceptable salts encompass especially the salts of those cations or the acid addi- tion salts of those acids whose cations and anions, respectively, have no adverse effect on the fungicidal action of said compounds. Suitable cations are thus in particular the ions of the alkali metals, preferably sodium and potassium, of the alkaline earth metals, preferably calcium, mag- nesium and barium, of the transition metals, preferably manganese, copper, zinc and iron, and also the ammonium ion which, if desired, may carry one to four Ci-C ₄ -alkyl substituents and/or one phenyl or benzyl substituent, preferably diisopropylammonium, tetramethylammonium, tet- rabutylammonium, trimethylbenzylammonium, furthermore phosphonium ions, sulfonium ions, preferably tri(Ci-C4-alkyl)sulfonium, and sulfoxonium ions, preferably tri(Ci-C4-alkyl)sulfoxonium. Anions of useful acid addition salts are primarily chloride, bromide, fluoride, hydrogensulfate, sulfate, dihydrogenphosphate, hydrogenphosphate, phosphate, nitrate, bicarbonate, carbonate, hexafluorosilicate, hexafluorophosphate, benzoate, and the anions of Ci-C4-alkanoic acids, preferably formate, acetate, propionate and butyrate. They can be formed by reacting such in- ventive compound with an acid of the corresponding anion, preferably of hydrochloric acid, hy- drobromic acid, sulfuric acid, phosphoric acid or nitric acid.

Examples of inorganic acids are hydrohalic acids, such as hydrogen fluoride, hydrogen chloride, hydrogen bromide and hydrogen iodide, carbonic acid, sulfuric acid, phosphoric acid and nitric acid.

Suitable organic acids are, for example, formic acid and alkanoic acids, such as acetic acid, trifluoroacetic acid, trichloroacetic acid and propionic acid, and also glycolic acid, thiocyanic ac- id, lactic acid, succinic acid, citric acid, benzoic acid and other arylcarboxylic acids, cinnamic acid, oxalic acid, alkylsulfonic acids (sulfonic acids having straight-chain or branched alkyl radi cals of 1 to 20 carbon atoms), arylsulfonic acids or aryldisulfonic acids (aromatic radicals, such as phenyl and naphthyl, which carry one or two sulfonic acid groups), alkylphosphonic acids (phosphonic acids having straight-chain or branched alkyl radicals with 1 to 20 carbon atoms), arylphosphonic acids or aryldiphosphonic acids (aromatic radicals, such as phenyl and naph- thyl, which carry one or two phosphoric acid radicals), where the alkyl or aryl radicals may carry further substituents, for example ptoluenesulfonic acid, salicylic acid, p-aminosalicylic acid, 2- phenoxybenzoic acid, 2-acetoxybenzoic acid etc. Suitable metal ions are in particular the ions of the elements of the second main group, in particular calcium and magnesium, of the third and fourth main group, in particular aluminum, tin and lead, and also of the elements of transition groups one to eight, in particular chromium, manganese, iron, cobalt, nickel, copper, zinc, and others. Particular preference is given to the metal ions of the elements of transition groups of the fourth period. The metals can be present in the various valencies that they can assume.

Therefore, according to the present invention, mefentrifluconazole can be used in form of any agriculturally acceptable salts or esters thereof.

Mefentrifluconazole comprises chiral centers and is generally obtained in the form of racemates. The R- and S-enantiomers of mefentrifluconazole (I) can be separated and isolated in pure form with methods known by the skilled person, e.g. by using chiral HPLC.

Therefore, according to the present invention, mefentrifluconazole can be used in form of

- a racemic mixture of the of the (R)-enantiomer and the (S)-enantiomer;

- a mixture with any other proportions of the (R)-enantiomer and the (S)-enantiomer;

- pure (R)-enantiomer or

- pure (S)-enantiomer. 11.1 (Z)-N-allyloxy-1-(2,4-dichlorophenyl)-2-imidazol-1-yl-ethani mine is known from CN 1465562;

11.2 3-chloro-4-(2,6-difluorophenyl)-6-methyl-5-phenyl-pyridazine is known from WO

2005/121 104;

11.3 N'-(2,5-dimethyl-4-phenoxy-phenyl)-N-ethyl-N-methyl-formamid ine is known from EP 2865265;

11.4 methyl (E)-2-[2-[(5-cyano-2-methyl-phenoxy)methyl]phenyl]-3-methoxy -prop-2-enoate is known from CN 1907024;

11.5 methyl (E)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-3-methoxy-prop -2-enoate is known from CN 1456054;

The following compounds are known from WO 2014/60177:

11.6 N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]butanamide;

11.7 N-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfa nyl-acetamide;

11.8 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)buta namide;

11.9 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)-2-m ethoxy-acetamide;

11.10 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-propyl-butanamide;

11.1 1 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methoxy-N-propyl-ac etamide;

11.12 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfanyl-N-pr opyl-acetamide;

11.13 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-N-(2-fluoroethyl)-2-m ethylsulfanyl-acetamide;

The following compounds are known from WO 2012/146125:

11.14 N'-(5-bromo-6-indan-2-yloxy-2-methyl-3-pyridyl)-N-ethyl-N-me thyl-formamidine;

11.15 N'-[5-bromo-6-[1-(3,5-difluorophenyl)ethoxy]-2-methyl-3-pyri dyl]-N-ethyl-N-methyl- formamidine;

11.16 N'-[5-bromo-6-(4-isopropylcyclohexoxy)-2-methyl-3-pyridyl]-N -ethyl-N-methyl- formamidine;

11.17 N'-[5-bromo-2-methyl-6-(1-phenylethoxy)-3-pyridyl]-N-ethyl-N -methyl-formamidine.

One typical problem arising in the control of phytopathogenic fungi lies in the need to reduce the dosage rates of the used active ingredients, in order to reduce or avoid unfavorable environ- mental or toxicological effects whilst still allowing effective control of the fungi.

There also exists the need for fungicidal agents that combine knock-down activity with prolonged control, that is, fast action with long lasting action.

Another difficulty in relation to the use of fungicides is that the repeated and exclusive applica- tion of an individual fungicidal compound leads in many cases to a rapid selection of harmful fungi, which have developed natural or adapted resistance against the active compound in question. Therefore, there is a need for fungicidal agents that help prevent or overcome re- sistance.

Another problem underlying the present invention is the desire for compositions that improve plants, a process which is commonly and hereinafter referred to as“plant health”. The term plant health comprises various sorts of improvements of plants that are not connected to the control of pests. For example, advantageous properties that may be mentioned are im- proved crop characteristics including: emergence, crop yields, protein content, oil content, starch content, more developed root system (improved root growth), improved stress tolerance (e.g. against drought, heat, salt, UV, water, cold), reduced ethylene (reduced production and/or inhibition of reception), tillering increase, increase in plant height, bigger leaf blade, less dead basal leaves, stronger tillers, greener leaf color, pigment content, photosynthetic activity, less input needed (such as fertilizers or water), less seeds needed, more productive tillers, earlier flowering, early grain maturity, less plant verse (lodging), increased shoot growth, enhanced plant vigor, increased plant stand and early and better germination; or any other advantages familiar to a person skilled in the art.

It was therefore an object of the present invention to provide fungicidal compositions which solve the problems of reducing the dosage rate and / or combining knock-down activity with prolonged control and / or avoiding the development of resistance and/or promoting the health of plants.

We have found that this object is in part or in whole achieved by the compositions according to the present invention.

Especially, it has been found that the compositions according to the present invention show markedly enhanced fungicidal action compared to the control rates with the individual corn- pounds and/or are suitable for improving the health of plants when applied to plants, parts of plants, seeds, or at their locus of growth.

It has been found that the action of the compositions according to the present invention goes far beyond the fungicidal and/or plant health improving action of the active compounds alone (syn- ergistic action).

Moreover, we have found that simultaneous, that is joint or separate, application of mefentriflu- conazole and at least one compound of component II), or successive application of mefentriflu- conazole and at least one compound of component II) allows enhanced control of harmful fungi, compared to the control rates that are possible with the individual compounds (synergistic corn- positions).

Moreover, we have found that simultaneous, that is joint or separate, application of mefentriflu- conazole and at least one compound of component II), or successive application of Mefentriflu- conazole and at least one compound of component II) provides enhanced plant health effects compared to the plant health effects that are possible with the individual compounds.

The compositions according to the present invention are compiled in the following Table A:

Compositions A-1 , A-2, A-3, A-6, A-7, A-8, A-9, A-10, A-11 , A-12, A-13, A-14, A-15, A-16, A-17 are preferred.

Compositions A-2, A-3, A-14, A-15, A-16, A-17 are especially preferred.

The ratio by weight of mefentrifluconazole I) and component II) is from 20000:1 to 1 :20000, preferably from 500:1 to 1 :500, more preferably from 100:1 to 1 :100, most preferably from 50:1 to 1 :50 and in particular from 20:1 to 1 :20, including also ratios from 10:1 to 1 :10, 1 :5 to 5:1 , or 1 :1 .

The compositions according to the present invention can further contain one or more active in- gredients selected from insecticides, fungicides, herbicides as additional active ingredient(s).

Said active ingredients can be selected from:

A) Respiration inhibitors

- Inhibitors of complex III at Q ₀ site: azoxystrobin (A.1.1 ), coumethoxystrobin (A.1.2), coumoxystrobin (A.1.3), dimoxystrobin (A.1.4), enestroburin (A.1.5), fenaminstrobin (A.1.6), fenoxystrobin/flufenoxystrobin (A.1.7), fluoxastrobin (A.1.8), kresoxim-methyl (A.1.9), man- destrobin (A.1.10), metominostrobin (A.1.1 1), orysastrobin (A.1.12), picoxystrobin (A.1.13), pyraclostrobin (A.1.14), pyrametostrobin (A.1.15), pyraoxystrobin (A.1.16), trifloxystrobin (A.1.17), 2-(2-(3-(2,6-dichlorophenyl)-1-methyl-allylideneaminooxymeth yl)-phenyl)- 2-methoxyimino-/V-methyl-acetamide (A.1.18), pyribencarb (A.1.19), triclopyricarb/chloro- dincarb (A.1.20), famoxadone (A.1.21), fenamidone (A.1.21), methyl-/V-[2-[(1 ,4-dimethyl- 5-phenyl-pyrazol-3-yl)oxylmethyl]phenyl]-/V-methoxy-carbamat e (A.1.22), metyltetrapole (A.1 25), (2^2£)-5-[1 -(2, 4-dichloiOphenyl)pyrazol-3-yl]-oxy-2-methoxyimino-/V, 3-dimethyl- pent-3-enamide (A.1 34), (^2£)-5-[1-(4-chlorophenyl)pyrazol-3-yl]oxy-2-methoxyimino- /V,3- dimethyl-pent-3-enamide (A.1.35), pyriminostrobin (A.1.36), bifujunzhi (A.1.37), 2-(ortho- ((2,5-dimethylphenyl-oxymethylen)phenyl)-3-methoxy-acrylic acid methylester (A.1.38);

- inhibitors of complex III at Q, site: cyazofamid (A.2.1), amisulbrom (A.2.2),

[(65,7 ?,8/^-8-benzyl-3-[(3-hydroxy-4-methoxy-pyridine-2-carbonyl)a mino]-6-methyl-4,9-di- oxo-1 ,5-dioxonan-7-yl] 2-methylpropanoate (A.2.3), fenpicoxamid (A.2.4), florylpicoxamid (A.2.5);

- inhibitors of complex II: benodanil (A.3.1 ), benzovindiflupyr (A.3.2), bixafen (A.3.3), boscalid (A.3.4), carboxin (A.3.5), fenfuram (A.3.6), fluopyram (A.3.7), flutolanil (A.3.8), fluxapyroxad (A.3.9), furametpyr (A.3.10), isofetamid (A.3.1 1), isopyrazam (A.3.12), mepronil (A.3.13), ox- ycarboxin (A.3.14), penflufen (A.3.15), penthiopyrad (A.3.16), pydiflumetofen (A.3.17), pyra- ziflumid (A.3.18), sedaxane (A.3.19), tecloftalam (A.3.20), thifluzamide (A.3.21), inpyrfluxam (A.3.22), pyrapropoyne (A.3.23), fluindapyr (A.3.28), methyl (£)-2-[2-[(5-cyano-2-methyl- phenoxy)methyl]phenyl]-3-methoxy-prop-2-enoate (A.3.30), isoflucypram (A.3.31), 2- (difluoromethyl)-/V-(1 ,1 ,3-trimethyl-indan-4-yl)pyridine-3-carboxamide (A.3.32), 2- (difluoromethyl)-/V-[(3/\ -1 ,1 ,3-trimethylindan-4-yl]pyridine-3-carboxamide (A.3.33), 2- (difluoromethyl)-/V-(3-ethyl-1 ,1-dimethyl-indan-4-yl)pyridine-3-carboxamide (A.3.34), 2- (difluoromethyl)-/V-[(3/\ -3-ethyl-1 ,1-dimethyl-indan-4-yl]pyridine-3-carboxamide (A.3.35), 2- (difluoromethyl)-/V-(1 ,1-dimethyl-3-propyl-indan-4-yl)pyridine-3-carboxamide (A.3.36), 2- (difluoromethyl)-/V-[(3/\ -1 ,1-dimethyl-3-propyl-indan-4-yl]pyridine-3-carboxamide (A.3.37), 2- (difluoromethyl)-/V-(3-isobutyl-1 ,1-dimethyl-indan-4-yl)pyridine-3-carboxamide (A.3.38), 2- (difluoromethyl)-/V-[(3/\ -3-isobutyl-1 ,1-dimethyl-indan-4-yl]pyridine-3-carboxamide (A.3.39);

- other respiration inhibitors: diflumetorim (A.4.1); nitrophenyl derivates: binapacryl (A.4.2), dinobuton (A.4.3), dinocap (A.4.4), fluazinam (A.4.5), meptyldinocap (A.4.6), ferimzone (A.4.7); organometal compounds: fentin salts, e. g. fentin-acetate (A.4.8), fentin chloride (A.4.9) or fentin hydroxide (A.4.10); ametoctradin (A.4.1 1); silthiofam (A.4.12);

B) Sterol biosynthesis inhibitors (SBI fungicides)

- C14 demethylase inhibitors: triazoles: azaconazole (B.1.1), bitertanol (B.1.2), bromu- conazole (B.1.3), cyproconazole (B.1.4), difenoconazole (B.1.5), diniconazole (B.1.6), dini- conazole-M (B.1.7), epoxiconazole (B.1.8), fenbuconazole (B.1.9), fluquinconazole (B.1.10), flusilazole (B.1.1 1 ), flutriafol (B.1.12), hexaconazole (B.1.13), imibenconazole (B.1.14), ip- conazole (B.1.15), metconazole (B.1.17), myclobutanil (B.1.18), oxpoconazole (B.1.19), paclobutrazole (B.1.20), penconazole (B.1.21 ), propiconazole (B.1.22), prothioconazole (B.1.23), simeconazole (B.1.24), tebuconazole (B.1.25), tetraconazole (B.1.26), triadimefon (B.1.27), triadimenol (B.1.28), triticonazole (B.1.29), uniconazole (B.1.30), 2-(2,4- difluorophenyl)-1 ,1-difluoro-3-(tetrazol-1-yl)-1-[5-[4-(2,2,2-trifluoroethoxy )phenyl]- 2-pyridyl]propan-2-ol (B.1.31), 2-(2,4-difluorophenyl)-1 ,1-difluoro-3-(tetrazol-1-yl)- 1-[5-[4-(trifluoromethoxy)phenyl]-2-pyridyl]propan-2-ol (B.1.32), ipfentrifluconazole (B.1.37), mefentrifluconazole (B.1.38), 2-(chloromethyl)-2-methyl-5-(p-tolylmethyl)-1-(1 ,2,4-triazol- 1-ylmethyl)cyclopentanol (B.1.43); imidazoles: imazalil (B.1.44), pefurazoate (B.1.45), pro- chloraz (B.1.46), triflumizol (B.1.47); pyrimidines, pyridines, piperazines: fenarimol (B.1.49), pyrifenox (B.1.50), triforine (B.1.51 ), [3-(4-chloro-2-fluoro-phenyl)-5-(2,4-difluoro- phenyl)isoxazol-4-yl]-(3-pyridyl)methanol (B.1.52); - Deltal 4-reductase inhibitors: aldimorph (B.2.1 ), dodemorph (B.2.2), dodemorph-acetate (B.2.3), fenpropimorph (B.2.4), tridemorph (B.2.5), fenpropidin (B.2.6), piperalin (B.2.7), spi- roxamine (B.2.8);

- Inhibitors of 3-keto reductase: fenhexamid (B.3.1 );

- Other Sterol biosynthesis inhibitors: chlorphenomizole (B.4.1 );

C) Nucleic acid synthesis inhibitors

- phenylamides or acyl amino acid fungicides: benalaxyl (C.1.1 ), benalaxyl-M (C.1.2), kiralaxyl (C.1.3), metalaxyl (C.1.4), metalaxyl-M (C.1.5), ofurace (C.1.6), oxadixyl (C.1.7);

- other nucleic acid synthesis inhibitors: hymexazole (C.2.1), octhilinone (C.2.2), oxolinic acid (C.2.3), bupirimate (C.2.4), 5-fluorocytosine (C.2.5), 5-fluoro-2-(p-tolylmethoxy)pyrimidin- 4-amine (C.2.6), 5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine (C.2.7), 5-fluoro- 2-(4-chlorophenylmethoxy)pyrimidin-4 amine (C.2.8);

D) Inhibitors of cell division and cytoskeleton

- tubulin inhibitors: benomyl (D.1.1 ), carbendazim (D.1.2), fuberidazole (D1.3), thiabendazole (D.1.4), thiophanate-methyl (D.1.5), pyridachlometyl (D.1.6), /V-ethyl-2-[(3-ethynyl-8-methyl- 6-quinolyl)oxy]butanamide (D.1.8), /V-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2- methylsulfanyl-acetamide (D.1.9), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-/V-(2- fluoroethyl)butanamide (D.1.10), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-/V-(2-fluoroethyl)-2- methoxy-acetamide (D.1.1 1), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-/V-propyl-butanamide (D.1.12), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methoxy-/V-propyl-a cetamide (D.1.13), 2- [(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methylsulfanyl-/V-pro pyl-acetamide (D.1.14),

2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-/V-(2-fluoroethyl)-2- methylsulfanyl-acetamide (D.1.15), 4-(2-bromo-4-fluoro-phenyl)-/V-(2-chloro-6-fluoro-phenyl)-2, 5-dimethyl-pyrazol-3-amine (D.1.16);

- other cell division inhibitors: diethofencarb (D.2.1), ethaboxam (D.2.2), pencycuron (D.2.3), fluopicolide (D.2.4), zoxamide (D.2.5), metrafenone (D.2.6), pyriofenone (D.2.7);

E) Inhibitors of amino acid and protein synthesis

- methionine synthesis inhibitors: cyprodinil (E.1.1), mepanipyrim (E.1.2), pyrimethanil (E.1.3);

- protein synthesis inhibitors: blasticidin-S (E.2.1 ), kasugamycin (E.2.2), kasugamycin hydro- chloride-hydrate (E.2.3), mildiomycin (E.2.4), streptomycin (E.2.5), oxytetracyclin (E.2.6);

F) Signal transduction inhibitors

- MAP / histidine kinase inhibitors: fluoroimid (F.1.1), iprodione (F.1.2), procymidone (F.1.3), vinclozolin (F.1.4), fludioxonil (F.1.5);

- G protein inhibitors: quinoxyfen (F.2.1 );

G) Lipid and membrane synthesis inhibitors

- Phospholipid biosynthesis inhibitors: edifenphos (G .1.1), iprobenfos (G.1.2), pyrazophos (G.1.3), isoprothiolane (G.1.4);

- lipid peroxidation: dicloran (G.2.1), quintozene (G.2.2), tecnazene (G.2.3), tolclofos-methyl (G.2.4), biphenyl (G.2.5), chloroneb (G.2.6), etridiazole (G.2.7);

- phospholipid biosynthesis and cell wall deposition: dimethomorph (G.3.1 ), flumorph (G.3.2), mandipropamid (G.3.3), pyrimorph (G.3.4), benthiavalicarb (G.3.5), iprovalicarb (G.3.6), valifenalate (G.3.7);

- compounds affecting cell membrane permeability and fatty acides: propamocarb (G.4.1 );

- inhibitors of oxysterol binding protein: oxathiapiprolin (G.5.1), 2-{3-[2-(1 -{[3,5-bis(d ifluoro- methyl-1 /7-pyrazol-1 -yl]acetyl}piperidin-4-yl)-1 ,3-thiazol-4-yl]-4,5-dihydro-1 ,2-oxazol-5-yl}- phenyl methanesulfonate (G.5.2), 2-{3-[2-(1-{[3,5-bis(difluoromethyl)-1 A pyrazol-l-yl]- acetyl}piperidin-4-yl) 1 ,3-thiazol-4-yl]-4,5-dihyd ro-1 ,2-oxazol-5-yl}-3-chlorophenyl methane- sulfonate (G.5.3), 4-[1-[2-[3-(difluoromethyl)-5-methyl-pyrazol-1-yl]acetyl]-4- piperidyl]-/V-te- tralin-1 -yl-pyhdine-2-carboxamide (G.5.4), 4-[1 -[2-[3,5-bis(difluoromethyl)pyrazol-1 -yl]acetyl]- 4-piperidyl]-/V-tetralin-1-yl-pyhdine-2-carboxamide (G.5.5), 4-[1-[2-[3-(difluoromethyl)-5-(tri- fluoromethyl)pyrazol-1-yl]acetyl]-4-piperidyl]-/V-tetralin-1 -yl-pyhdine-2-carboxamide (G.5.6), 4-[1-[2-[5-cyclopropyl-3-(difluoromethyl)pyrazol-1-yl]acetyl ]-4-piperidyl]-/V-tetralin-1-yl-pyri- dine-2-carboxamide (G.5.7), 4-[1-[2-[5-methyl-3-(trifluoromethyl)pyrazol-1-yl]acetyl]-4- piperi- dyl]-/V-tetralin-1-yl-pyhdine-2-carboxamide (G.5.8), 4-[1-[2-[5-(difluoromethyl)-3-(trifluoro- methyl)pyrazol-1-yl]acetyl]-4-piperidyl]-/V-tetralin-1-yl-py ridine-2-carboxamide (G.5.9),

4-[1 -[2-[3,5-bis(trifluoromethyl)pyrazol-1 -yl]acetyl]-4-piperidyl]-AAtetralin-1 -yl-pyridine-2-car- boxamide (G.5.10), (4-[1-[2-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]acet yl]-4-piperidyl]- /V-tetralin-1-yl-pyhdine-2-carboxamide (G.5.11 );

H) Inhibitors with Multi Site Action

- inorganic active substances: Bordeaux mixture (H.1.1 ), copper (H.1.2), copper acetate

(H.1.3), copper hydroxide (H.1.4), copper oxychloride (H.1.5), basic copper sulfate (H.1.6), sulfur (H.1.7);

- thio- and dithiocarbamates: ferbam (H.2.1 ), mancozeb (H.2.2), maneb (H.2.3), metam

(H.2.4), metiram (H.2.5), propineb (H.2.6), thiram (H.2.7), zineb (H.2.8), ziram (H.2.9);

- organochlorine compounds: anilazine (H.3.1 ), chlorothalonil (H.3.2), captafol (H.3.3), captan (H.3.4), folpet (H.3.5), dichlofluanid (H.3.6), dichlorophen (H.3.7), hexachlorobenzene (H.3.8), pentachlorphenole (H.3.9) and its salts, phthalide (H.3.10), tolylfluanid (H.3.11 );

- guanidines and others: guanidine (H.4.1 ), dodine (H.4.2), dodine free base (H.4.3),

guazatine (H.4.4), guazatine-acetate (H.4.5), iminoctadine (H.4.6), iminoctadine-triacetate (H.4.7), iminoctadine-tris(albesilate) (H.4.8), dithianon (H.4.9), 2,6-dimethyl-1 A/,5A ^L [1 ,4]di- thiino[2,3-c:5,6-c']dipyrrole-1 ,3,5,7(2A/,6A)-tetraone (H.4.10);

I) Cell wall synthesis inhibitors

- inhibitors of glucan synthesis: validamycin (1.1.1 ), polyoxin B (1.1.2);

- melanin synthesis inhibitors: pyroquilon (1.2.1), tricyclazole (1.2.2), carpropamid (1.2.3), dicy- clomet (1.2.4), fenoxanil (I.2.5);

J) Plant defence inducers

- acibenzolar-S-methyl (J.1.1), probenazole (J.1.2), isotianil (J.1.3), tiadinil (J.1.4), prohexa- dione-calcium (J.1.5); phosphonates: fosetyl (J.1.6), fosetyl-aluminum (J.1.7), phosphorous acid and its salts (J.1.8), calcium phosphonate (J.1.11 ), potassium phosphonate (J.1.12), potassium or sodium bicarbonate (J.1.9), 4-cyclopropyl-/V-(2,4-dimethoxyphenyl)thiadiazole-

5-carboxamide (J.1.10);

K) Unknown mode of action

- bronopol (K.1.1 ), chinomethionat (K.1.2), cyflufenamid (K.1.3), cymoxanil (K.1.4), dazomet (K.1.5), debacarb (K.1.6), diclocymet (K.1.7), diclomezine (K.1.8), difenzoquat (K.1.9), di- fenzoquat-methylsulfate (K.1.10), diphenylamin (K.1.11 ), fenitropan (K.1.12), fenpyrazamine (K.1.13), flumetover (K.1.14), flusulfamide (K.1.15), flutianil (K.1.16), harpin (K.1.17), metha- sulfocarb (K.1.18), nitrapyrin (K.1.19), nitrothal-isopropyl (K.1.20), tolprocarb (K.1.21 ), oxin- copper (K.1.22), proquinazid (K.1.23), tebufloquin (K.1.24), tecloftalam (K.1.25), triazoxide (K.1.26), /V ⁱ (4-(4-chloro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-p henyl)-/V-ethyl-/V-methyl formamidine (K.1.27), /V ⁱ (4-(4-fluoro-3-trifluoromethyl-phenoxy)-2,5-dimethyl-p henyl)-/V-eth- yl-/V-methyl formamidine (K.1.28), /V ⁱ [4-[[3-[(4-chlorophenyl)methyl]-1 ,2,4-thiadiazol-5-yl]- oxy]-2,5-dimethyl-phenyl]-/V-ethyl-/V-methyl-formamidine (K.1.29), /V^S-bromo-e-indan^-yl- oxy-2-methyl-3-pyridyl)-/V-ethyl-/V-methyl-formamidine (K.1.30), LL-[5-ΐ3GqGTΐo-6-[1-(3,5^iίIii- orophenyl)ethoxy]-2-methyl-3-pyridyl]-/V-ethyl-/V-methyl-for mamidine (K.1.31), /V^S-bromo- 6-(4-isopropylcyclohexoxy)-2-methyl-3-pyridyl]-/V-ethyl-/V-m ethyl-formamidine (K.1.32), /V ⁱ [5-bromo-2-methyl-6-(1-phenylethoxy)-3-pyridyl]-/V-eth yl-/V-methyl-formamidine (K.1.33), /V ⁱ (2-methyl-5-trifluoromethyl-4-(3-trimethylsilanyl-prop oxy)-phenyl)-/V-ethyl-/V-methyl forma- midine (K.1.34), /V ⁱ (5-difluoromethyl-2-methyl-4-(3-trimethylsilanyl-propo xy)-phenyl)-/V-ethyl- /V-methyl formamidine (K.1.35), 2-(4-chloro-phenyl)-/V-[4-(3,4-dimethoxy-phenyl)-isoxazol- 5-yl]-2-prop-2-ynyloxy-acetamide (K.1.36), 3-[5-(4-chloro-phenyl)-2,3-dimethyl-isoxazolidin- 3-yl]-pyridine (pyrisoxazole) (K.1.37), 3-[5-(4-methylphenyl)-2,3-dimethyl-isoxazolidin-3 yl]- pyridine (K.1.38), 5-chloro-1-(4,6-dimethoxy-pyrimidin-2-yl)-2-methyl-1 TT-benzoimidazole (K.1.39), ethyl (2)-3-amino-2-cyano-3-phenyl-prop-2-enoate (K.1.40), picarbutrazox (K.1.41), pentyl /V-[6-[[(2)-[(1-methyltetrazol-5-yl)-phenyl-methylene]amino] oxymethyl]-2-pyridyl]carba- mate (K.1.42), but-3-ynyl /V-[6-[[(2)-[(1-methyltetrazol-5-yl)-phenyl-methylene]amino] oxy- methyl]-2-pyridyl]carbamate (K.1.43), ipflufenoquin (K.1.44), quinofumelin (K.1.47), 2-(6- benzyl-2-pyridyl)quinazoline (K.1.50), 2-[6-(3-fluoro-4-methoxy-phenyl)-5-methyl-2- pyridyl]quinazoline (K.1.51), dichlobentiazox (K.1.52), /V ⁱ (2,5-dimethyl-4-phenoxy-phenyl)-/V- ethyl-/V-methyl-formamidine (K.1.53), pyrifenamine (K.1.54);

L) Biopesticides

L1 ) Microbial pesticides with fungicidal, bactericidal, viricidal and/or plant defense activator activity: Ampelomyces quisqua/is, Aspergillus flavus, Aureobasidium pullulans, Bacillus altitudinis, B. amyloliquefaciens, B. megaterium, B. mojavensis, B. mycoides, B. pumi- lus, B. simplex, B. so/isa/si, B. subtiHs, B. subti/is var. amyloliquefaciens, Candida oieo- phila, C. saitoana, Clavibacter michiganensis (bacteriophages), Coniothyrium minitans, Cryphonectria parasitica, Cryptococcus aibidus, Diiophosphora aiopecuri, Fusarium oxysporum, Cionostachys rosea f . eaten uiate (also named Giiociadium catenuiatum), Giiociadium roseum, Lysobacter antibioticus, L. enzymogenes, Metschnikowia fructi- coia, Microdochium dimerum, Microsphaeropsis ochracea, Muscodor aibus, Paeni- bacHius aivei, Paenibaciiius epiphyticus, P. poiymyxa, Pantoea vagans, Peniciiiium biiaiae, P hie biops is gig an tea, Pseudomonas s p . , Pseudomonas chioraphis, Pseudo- zyma fioccuiosa, Pichia anomaia, Pythium oiigandrum, Sphaerodes mycoparasitica, Streptomyces griseoviridis, S. iydicus, S. vioiaceusniger, Taiaromyces fiavus, Tricho- derma aspereiioides, T. aspereiium, T atroviride, T fertile, T gamsii, T. harmatum, T. harzianum, T. poiysporum, T. stromaticum, T. virens, T. viride, Typhuia phacorrhiza, Uiociadium oudemansii, Verticiiiium dahlia, zucchini yellow mosaic virus (avirulent strain);

L2) Biochemical pesticides with fungicidal, bactericidal, viricidal and/or plant defense acti vator activity: harpin protein, Reynoutria sacha/inensis extract;

L3) Microbial pesticides with insecticidal, acaricidal, molluscidal and/or nematicidal activity:

Agrobacterium radiobacter, Bacillus cere us, B. firm us, B. thuringiensis, B. thuringiensis ssp. aizawai, B. t. ssp. israe/ensis, B. t. ssp. gaiieriae, B. t. ssp. kurstaki, B. t. ssp. tene- brionis, Beauveria bassiana, B. brongniartii, Burkholderia s p p . , Chromobacterium sub- tsugae, Cydia pomonella granulovirus (CpGV), Cryptoph/ebia leucotreta granulovirus (CrleGV), F/avobacterium spp., HeUcoverpa armigera nucleopolyhedrovirus

(HearNPV), HeUcoverpa zea nucleopolyhedrovirus (HzNPV), He/ico verpa zea single capsid nucleopolyhedrovirus (HzSNPV), Heterorhabditis bacteriophora, isaria fumoso- rosea, LecaniciWum longisporum, L. muscarium, Metarhizium anisopHae, M. anisoptiae var. anisopHae, M. anisopHae vat. acrid um, Nomuraea riieyi, Paeciiomyces fumoso- roseus, P. Hiacinus, Paenibaciiius popiiiiae, Pasteuria spp., P. nishizawae, P. pene trans, P. ramosa, P. thornea, P. usgae, Pseudomonas f/uorescens, Spodoptera iitto- raiis nucleopolyhedrovirus (SpliNPV), Steinernema carpocapsae, S. feitiae, S.

kraussei, Streptomyces gaibus, S. microfiavusr,

L4) Biochemical pesticides with insecticidal, acaricidal, molluscidal, pheromone and/or ne- maticidal activity: L-carvone, citral, (F^- ^-dodecadien-l-yl acetate, ethyl formate, {E,Z)-2, 4-ethyl decadienoate (pear ester), Z,Z,E)-Ί ,l 1 ,13-hexadecatrienal, heptyl buty- rate, isopropyl myristate, lavanulyl senecioate, cis-jasmone, 2-methyl 1 -butanol, methyl eugenol, methyl jasmonate, (F,2)-2,13-octadecadien-1-ol, (F,2)-2,13-octadecadien-1-ol acetate, (£;2)-3,13-octadecadien-1-ol, (/ )-1-octen-3-ol, pentatermanone,

(F,Z;2)-3,8,11-tetradecatrienyl acetate, ( ;£)-9,12-tetradecadien-1-yl acetate,

(2)-7-tetradecen-2-one, (2)-9-tetradecen-1-yl acetate, (2)-1 1-tetradecenal, (2)-1 1-tetra- decen-1-ol, extract of Chenopodium ambrosiode s, Neem oil, Quillay extract;

L5) Microbial pesticides with plant stress reducing, plant growth regulator, plant growth promoting and/or yield enhancing activity: Azospiriiium amazonense, A. brasi/ense, A. Hpoferum, A. irakense, A. haiopraeferens, Bradyrhizobium spp., B. eikanii, B.japoni- cum, B. Haoningense, B. lupin i, Deiftia acidovorans, G/omus intraradices, Mesorhizo- bium spp., Rhizobium ieguminosarum bv. phased i, R. i. bv. trifoiii, R. i. bv. viciae, R. tropici, Sinorhizobium meiHoti,

M) Growth regulators

abscisic acid (M.1.1 ), amidochlor, ancymidol, 6-benzylaminopurine, brassinolide, butralin, chlormequat, chlormequat chloride, choline chloride, cyclanilide, daminozide, dikegulac, dime- thipin, 2,6-dimethylpuridine, ethephon, flumetralin, flurprimidol, fluthiacet, forchlorfenuron, gib- berellic acid, inabenfide, indole-3-acetic acid , maleic hydrazide, mefluidide, mepiquat, mepiquat chloride, naphthaleneacetic acid, /V-6-benzyl adenine, paclobutrazol, prohexadione, prohexadi- one-calcium, prohydrojasmon, thidiazuron, triapenthenol, tributyl phosphorotrithioate,

2,3,5-tri-iodobenzoic acid , trinexapac-ethyl, uniconazole;

N) Herbicides from classes N.1 to N.15

N.1 Lipid biosynthesis inhibitors: alloxydim, alloxydim-sodium, butroxydim, clethodim,

clodinafop, clodinafop-propargyl, cycloxydim, cyhalofop, cyhalofop-butyl, diclofop, diclofop- methyl, fenoxaprop, fenoxaprop-ethyl, fenoxaprop-P, fenoxaprop-P-ethyl, fluazifop, fluazifop- butyl, fluazifop-P, fluazifop-P-butyl, haloxyfop, haloxyfop-methyl, haloxyfop-P, haloxyfop-P- methyl, metamifop, pinoxaden, profoxydim, propaquizafop, quizalofop, quizalofop-ethyl, quizalofop-tefuryl, quizalofop-P, quizalofop-P-ethyl, quizalofop-P-tefuryl, sethoxydim, tepra- loxydim, tralkoxydim, 4-(4'-chloro-4-cyclo ^~, propyl-2'-fluoro[1 ,1 '-biphenyl]-3-yl)-5-hydroxy- 2,2,6,6-tetramethyl-2/7 ^L pyran-3(6A7)-one (1312337-72-6); 4-(2',4'-dichloro-4-cyclopropyl[1 ,1'- biphenyl]-3-yl)-5-hydroxy-2,2,6,6-tetramethyl-277-pyran-3(6A 7)-one (1312337-45-3); 4-(4'-chloro-4-ethyl-2'-fluoro[1 '-biphenyll-S-y -S-hydroxy^^^^-tetramethyl^A pyran- 3(6A)-one (1033757-93-5); 4-(2',4'-dichloro-4-ethyl[1 ,1'-biphenyl]-3-yl)-2,2,6,6-tetramethyl- 2^ ^ί -pyran-3,5(4A/,6^)-dione (1312340-84-3); 5-(acetyloxy)-4-(4'-chloro-4-cyclopropyl-2'- fluoro[1 ,1 '-biphenyl]-3-yl)-3,6-dihydro-2,2,6,6-tetramethyl-2/7-pyran- 3-one (1312337-48-6);

5-(acetyloxy)-4-(2 ^' ,4'-dichloro-4-cyclopropyl- [1 , 1 '-biphenyl]-3-yl)-3,6-dihydro-2,2,6,6-tetra- methyl-2/7-pyran-3-one; 5-(acetyloxy)-4-(4'-chloro-4-ethyl-2'-fluoro[1 ,1 '-biphenyl]-3-yl)- 3,6-dihydro-2,2,6,6-tetramethyl-2/7-pyran-3-one (1312340-82-1); 5-(acetyloxy)-4-(2',4'-di- chloro-4-ethyl[1 ,1 '-biphenyll-S-y -S^-dihydro^^^^-tetramethyl^/T-pyran-S-one (1033760- 55-2); 4-(4'-chloro-4-cyclopropyl-2'-fluoro[1 ,1 '-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl- 5-oxo-2/7-pyran-3-yl carbonic acid methyl ester (1312337-51-1); 4-(2 ^' ,4'-dichloro -4-cyclo- propyl- [1 ,1'-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl-5-oxo-2/ 7-pyran-3-yl carbonic ac- id methyl ester; 4-(4'-chloro-4-ethyl-2'-fluoro[1 ,1 '-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetra- methyl-5-oxo-277-pyran-3-yl carbonic acid methyl ester (1312340-83-2); 4-(2',4'-dichloro- 4-ethyh[1 ,1 '-biphenyl]-3-yl)-5,6-dihydro-2,2,6,6-tetramethyl-5-oxo-2A7 ^L pyran-3-yl carbonic ac- id methyl ester (1033760-58-5); benfuresate, butylate, cycloate, dalapon, dimepiperate, EPTC, esprocarb, ethofumesate, flupropanate, molinate, orbencarb, pebulate, prosulfocarb, TCA, thiobencarb, tiocarbazil, triallate, vernolate;

N.2 ALS inhibitors: amidosulfuron, azimsulfuron, bensulfuron, bensulfuron-methyl, chlorimuron, chlorimuron-ethyl, chlorsulfuron, cinosulfuron, cyclosulfamuron, ethametsulfuron, ethamet- sulfuron-methyl, ethoxysulfuron, flazasulfuron, flucetosulfuron, flupyrsulfuron, flupyrsulfuron- methyl-sodium, foramsulfuron, halosulfuron, halosulfuron-methyl, imazosulfuron, iodosulfu- ron, iodosulfuron-methyl-sodium, iofensulfuron, iofensulfuron-sodium, mesosulfuron, meta- zosulfuron, metsulfuron, metsulfuron-methyl, nicosulfuron, orthosulfamuron, oxasulfuron, primisulfuron, primisulfuron-methyl, propyrisulfuron, prosulfuron, pyrazosulfuron, pyrazo- sulfuron-ethyl, rimsulfuron, sulfometuron, sulfometuron-methyl, sulfosulfuron, thifensulfuron, thifensulfuron-methyl, triasulfuron, tribenuron, tribenuron-methyl, trifloxysulfuron, triflusul- furon, triflusulfuron-methyl, tritosulfuron, imazamethabenz, imazamethabenz-methyl, imaza- mox, imazapic, imazapyr, imazaquin, imazethapyr; cloransulam, cloransulam-methyl, diclo- sulam, flumetsulam, florasulam, metosulam, penoxsulam, pyrimisulfan, pyroxsulam; bispyri- bac, bispyribac-sodium, pyribenzoxim, pyriftalid, pyriminobac, pyriminobac-methyl, pyrithio- bac, pyrithiobac-sodium, 4-[[[2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]phenyl]methyl]amino ]- benzoic acid-1 -methyhethyl ester (420138-41-6), 4-[[[2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]- phenylj-'methyllaminol-benzoic acid propyl ester (420138-40-5), /V-(4-bromophenyl)- 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]benzenemethanamine (420138-01-8); flucarbazone, flu- carbazone-sodium, propoxycarbazone, propoxycarbazone-sodium, thiencarbazone, thien- carbazone-methyl; triafamone;

N.3 Photosynthesis inhibitors: amicarbazone; chlorotriazine; ametryn, atrazine, chloridazone, cyanazine, desmetryn, dimethametryn,hexazinone, metribuzin, prometon, prometryn, pro- pazine, simazine, simetryn, terbumeton, terbuthylazin, terbutryn, trietazin; chlorobromuron, chlorotoluron, chloroxuron, dimefuron, diuron, fluometuron, isoproturon, isouron, linuron, metamitron, methabenzthiazuron, metobenzuron, metoxuron, monolinuron, neburon, sidu- ron, tebuthiuron, thiadiazuron, desmedipham, karbutilat, phenmedipham, phenmedipham- ethyl, bromofenoxim, bromoxynil and its salts and esters, ioxynil and its salts and esters, bromacil, lenacil, terbacil, bentazon, bentazon-sodium, pyridate, pyridafol, pentanochlor, propanil; diquat, diquat-dibromide, paraquat, paraquat-dichloride, paraquat-dimetilsulfate;

N.4 protoporphyrinogen-IX oxidase inhibitors: acifluorfen, acifluorfen-sodium, azafenidin, ben- carbazone, benzfendizone, bifenox, butafenacil, carfentrazone, carfentrazone-ethyl, chlor- methoxyfen, cinidon-ethyl, fluazolate, flufenpyr, flufenpyr-ethyl, flumiclorac, flumiclorac-pen- tyl, flumioxazin, fluoroglycofen, fluoroglycofen-ethyl, fluthiacet, fluthiacet-methyl, fomesafen, halosafen, lactofen, oxadiargyl, oxadiazon, oxyfluorfen, pentoxazone, profluazol, pyraclonil, pyraflufen, pyraflufen-ethyl, saflufenacil, sulfentrazone, thidiazimin, tiafenacil, trifludimoxazin, ethyl [3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-diox o-1 ,2,3,4-tetrahydropyrimi- din-3-yl)phenoxy]-2-pyridyloxy]acetate (353292-31-6), /V-ethyl-3-(2,6-dichloro-4-trifluoro- methylphenoxy)-5-methyl-1 //-pyrazole-1 -carboxamide (452098-92-9), /V-tetrahydrofurfuryl- 3-(2,6-dichloro-4-trifluoromethylphenoxy)-5-methyl-1 //-pyrazole-1 -carboxamide (915396-43- 9), /V-ethyl-3-(2-chloro-6-fluoro-4-trifluoromethyhphenoxy)-5-me thyl-1 //-pyrazole-1 -carbox- amide (452099-05-7), /V-tetrahydro ^-, furfuryl-3-(2-chloro-6-fluoro-4-trifluoro ^-, methylphenoxy)- 5-methyl-1 //-pyrazole-1 -carboxamide (452100-03-7), 3-[7-fluoro-3-oxo-4-(prop-2-ynyl)-

3.4-dihydro-2//-benzo[1 ,4]oxazin-6-yl]-1 ,5-dimethyl-6-thioxo-[1 ,3,5]triazinan-2,4-dione (451484-50-7), 2-(2,2,7-trifluoro-3-oxo-4-prop-2-ynyl-3,4-dihydro-2//-benzo [1 ,4]oxazin-6-yl)- 4,5,6,7-tetrahydro-isoindole-1 ,3-dione (1300118-96-0), l-methyl-e-trifluoro^methyl- 3-(2,2,7-tri-fluoro-3-oxo-4-prop-2-ynyl-3,4-dihydro-2//-benz o[1 ,4]oxazin-6-yl)-1 //-pyrimidine-

2.4-dione (1304113-05-0), methyl (£)-4-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1 //-methyl- pyrazol-3-yl]-4-fluoro-phenoxy]-3-methoxy-but-2-enoate (948893-00-3), 3-[7-chloro-5-fluoro- 2-(trifluoromethyl)-1 //-benzimidazol-4-yl]-1 -methyl-6-(trifluoromethyl)-1 //-pyrimidine-2, 4-di- one (212754-02-4);

N.5 Bleacher herbicides: beflubutamid, diflufenican, fluridone, flurochloridone, flurtamone,

norflurazon, picolinafen, 4-(3-trifluoromethyhphenoxy)-2-(4-trifluoromethylphenyl)pyri midine (180608-33-7); benzobicyclon, benzofenap, bicyclopyrone, clomazone, fenquintrione, isoxaflutole, mesotrione, pyrasulfotole, pyrazolynate, pyrazoxyfen, sulcotrione, tefuryltrione, tembotrione, tolpyralate, topramezone; aclonifen, amitrole, flumeturon;

N.6 EPSP synthase inhibitors: glyphosate, glyphosate-isopropylammonium, glyposate- potassium, glyphosate-trimesium (sulfosate);

N.7 Glutamine synthase inhibitors: bilanaphos (bialaphos), bilanaphos-sodium, glufosinate, glufosinate-P, glufosinate-ammonium;

N.8 DHP synthase inhibitors: asulam;

N.9 Mitosis inhibitors: benfluralin, butralin, dinitramine, ethalfluralin, fluchloralin, oryzalin, pen- dimethalin, prodiamine, trifluralin; amiprophos, amiprophos-methyl, butamiphos; chlorthal, chlorthal-dimethyl, dithiopyr, thiazopyr, propyzamide, tebutam; carbetamide, chlorpropham, flamprop, flamprop-isopropyl, flamprop-methyl, flamprop-M-isopropyl, flamprop-M-methyl, propham;

N.10 VLCFA inhibitors: acetochlor, alachlor, butachlor, dimethachlor, dimethenamid, dimethen- amid-P, metazachlor, metolachlor, metolachlor-S, pethoxamid, pretilachlor, propachlor, prop- isochlor, thenylchlor, flufenacet, mefenacet, diphenamid, naproanilide, napropamide, napro- pamide-M, fentrazamide, anilofos, cafenstrole, fenoxasulfone, ipfencarbazone, piperophos, pyroxasulfone, isoxazoline compounds of the formulae 11.1 , II.2, II.3, II.4, II.5, II.6, II.7, II.8 and II.9

N.1 1 Cellulose biosynthesis inhibitors: chlorthiamid, dichlobenil, flupoxam, indaziflam, isoxaben, triaziflam, 1 -cyclohexyl-5-pentafluorphenyloxy-14-[1 ,2,4,6]thiatriazin-3-ylamine (175899-01 - 1 );

N.12 Decoupler herbicides: dinoseb, dinoterb, DNOC and its salts;

N.13 Auxinic herbicides: 2,4-D and its salts and esters, clacyfos, 2,4-DB and its salts and es- ters, aminocyclopyrachlor and its salts and esters, aminopyralid and its salts such as amino- pyralid-dimethylammonium, aminopyralid-tris(2-hydroxypropyl)ammonium and its esters, benazolin, benazolin-ethyl, chloramben and its salts and esters, clomeprop, clopyralid and its salts and esters, dicamba and its salts and esters, dichlorprop and its salts and esters, di- chlorprop-P and its salts and esters, fluroxypyr, fluroxypyr-butometyl, fluroxypyr-meptyl, ha- lauxifen and its salts and esters (943832-60-8); MCPA and its salts and esters, MCPA- thioethyl, MCPB and its salts and esters, mecoprop and its salts and esters, mecoprop-P and its salts and esters, picloram and its salts and esters, quinclorac, quinmerac, TBA (2,3,6) and its salts and esters, triclopyr and its salts and esters, 4-amino-3-chloro- 6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-car boxylic acid, benzyl 4-amino- 3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyrid ine-2-carboxylate (1390661 -72- 9); N.14 Auxin transport inhibitors: diflufenzopyr, diflufenzopyr-sodium, naptalam, naptalam- sodium;

N.15 Other herbicides: bromobutide, chlorflurenol, chlorflurenol-methyl, cinmethylin, cumyluron, cyclopyrimorate (499223-49-3) and its salts and esters, dalapon, dazomet, difenzoquat, di- fenzoquat-metilsulfate, dimethipin, DSMA, dymron, endothal and its salts, etobenzanid, flu- renol, flurenol-butyl, flurprimidol, fosamine, fosamine-ammonium, indanofan, maleic hydra- zide, mefluidide, metam, methiozolin (403640-27-7), methyl azide, methyl bromide, methyl- dymron, methyl iodide, MSMA, oleic acid, oxaziclomefone, pelargonic acid, pyributicarb, quinoclamine, tridiphane;

O) Insecticides from classes 0.1 to 0.29

O.1 Acetylcholine esterase (AChE) inhibitors: aldicarb, alanycarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, trimethacarb, XMC, xylylcarb, triazamate; acephate, aza- methiphos, azinphos-ethyl, azinphosmethyl, cadusafos, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos/ DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfoton, EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion, fenthion, fosthiazate, heptenophos, imicyafos, isofenphos, isopropyl O-(methoxyaminothio-phosphoryl) salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosa- lone, phosmet, phosphamidon, phoxim, pirimiphos- methyl, profenofos, propetamphos, pro- thiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon, vamidothion;

0.2 GABA-gated chloride channel antagonists: endosulfan, chlordane; ethiprole, fipronil,

flufiprole, pyrafluprole, pyriprole;

0.3 Sodium channel modulators: acrinathrin, allethrin, d-cis-trans allethrin, d-trans allethrin, bifenthrin, kappa-bifenthrin, bioallethrin, bioallethrin S-cylclopentenyl, bioresmethrin, cyclo- prothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cy- permethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, empenthrin, esfenvalerate, etofenprox, fenpropathrin, fen- valerate, flucythrinate, flumethrin, tau-fluvalinate, halfenprox, heptafluthrin, imiprothrin, me- perfluthrin, metofluthrin, momfluorothrin, epsilon-momfluorothrin, permethrin, phenothrin, prallethrin, profluthrin, pyrethrin (pyrethrum), resmethrin, silafluofen, tefluthrin, kappa- tefluthrin, tetramethylfluthrin, tetramethrin, tralomethrin, transfluthrin; DDT, methoxychlor;

0.4 Nicotinic acetylcholine receptor agonists (nAChR): acetamiprid, clothianidin, cycloxaprid, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxam; 4,5-dihydro-/V-nitro- 1 -(2-oxiranylmethyl)-1 TT-imidazol^-amine, (2£)-1 -[(6-chloropyridin-3-yl)methyl]-/V ^: -nitro-2- pentylidenehydrazinecarboximidamide; 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5- propoxy-1 ,2,3,5,6,7-hexahydroimidazo[1 ,2-a]pyridine; nicotine; sulfoxaflor, flupyradifurone, triflumezopyrim;

0.5 Nicotinic acetylcholine receptor allosteric activators: spinosad, spinetoram;

0.6 Chloride channel activators: abamectin, emamectin benzoate, ivermectin, lepimectin, mil- bemectin; 0.7 Juvenile hormone mimics: hydroprene, kinoprene, methoprene; fenoxycarb, pyriproxyfen;

0.8 miscellaneous non-specific (multi-site) inhibitors: methyl bromide and other alkyl halides; chloropicrin, sulfuryl fluoride, borax, tartar emetic;

0.9 Chordotonal organ TRPV channel modulators: pymetrozine, pyrifluquinazon; flonicamid;

0.10 Mite growth inhibitors: clofentezine, hexythiazox, diflovidazin; etoxazole;

0.1 1 Microbial disruptors of insect midgut membranes: Bacillus thuringiensis, Bacillus sphaeri- cus and the insecticdal proteins they produce: Bacillus thuringiensis subsp. israe/ensis, Ba cillus sphaericus, Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp.

kurstaki, Bacillus thuringiensis subsp. tenebrionis, the Bt crop proteins: CrylAb, CrylAc, Cryl Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34/35Ab1 ;

0.12 Inhibitors of mitochondrial ATP synthase: diafenthiuron; azocyclotin, cyhexatin, fenbutatin oxide, propargite, tetradifon;

0.13 Uncouplers of oxidative phosphorylation via disruption of the proton gradient: chlorfenapyr, DNOC, sulfluramid;

0.14 Nicotinic acetylcholine receptor (nAChR) channel blockers: bensultap, cartap hydrochlo- ride, thiocyclam, thiosultap sodium;

0.15 Inhibitors of the chitin biosynthesis type 0: bistrifluron, chlorfluazuron, diflubenzuron, flu- cycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, triflumuron;

0.16 Inhibitors of the chitin biosynthesis type 1 : buprofezin;

0.17 Moulting disruptors: cyromazine;

0.18 Ecdyson receptor agonists: methoxyfenozide, tebufenozide, halofenozide, fufenozide, chromafenozide;

0.19 Octopamin receptor agonists: amitraz;

0.20 Mitochondrial complex III electron transport inhibitors: hydramethylnon, acequinocyl,

fluacrypyrim, bifenazate;

0.21 Mitochondrial complex I electron transport inhibitors: fenazaquin, fenpyroximate, pyrimidif- en, pyridaben, tebufenpyrad, tolfenpyrad; rotenone;

0.22 Voltage-dependent sodium channel blockers: indoxacarb, metaflumizone, 2-[2-(4-cyano- phenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-/V-[4-(difl uoromethoxy)phenyl]-hydrazine- carboxamide, /V-(3-chloro-2-methylphenyl)-2-[(4-chlorophenyl)-[4-[methyl( methylsulfonyl)- amino]phenyl]methylene]-hydrazinecarboxamide;

0.23 Inhibitors of the of acetyl CoA carboxylase: spirodiclofen, spiromesifen, spirotetramat, spi- ropidion;

0.24 Mitochondrial complex IV electron transport inhibitors: aluminium phosphide, calcium

phosphide, phosphine, zinc phosphide, cyanide;

0.25 Mitochondrial complex II electron transport inhibitors: cyenopyrafen, cyflumetofen;

0.26 Ryanodine receptor-modulators: flubendiamide, chlorantraniliprole, cyantraniliprole, cycla- niliprole, tetraniliprole; (/\ -3-chloro-/V-{2-methyl-4-[1 ,2,2,2 -tetrafluoro-1 -(trifluoromethyl)- ethyl]phenyl}-A ^e -(1-methyl-2-methylsulfonylethyl)phthalamide, (S)-3-chloro-/V-{2-methyl- 4-[1 ,2,2,2-tetrafluoro-1 -(trifluoromethyl)ethyl]phenyl}-A ^e -(1 -methyl-2-methylsulfonylethyl)- phthalamide, methyl-2-[3,5-dibromo-2-({[3-bromo-1 -(3-chloropyridin-2-yl)-1 /7-pyrazol-5-yl]- carbonyl}amino)benzoyl]-1 ,2-dimethylhydrazinecarboxylate; /V-[4,6-dichloro-2-[(diethyl- lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-(3-chloro-2-pyri dyl)-5-(trifluoromethyl)pyrazole- 3-carboxamide; /V-[4-chloro-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-6 -methyl-phenyl]- 2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyrazole-3-carboxa mide; /V-[4-chloro-2-[(di-2-propyl- lambda-4-sulfanylidene)carbamoyl]-6-methyl-phenyl]-2-(3-chlo ro-2-pyridyl)-5-(trifluorometh- yl)pyrazole-3-carboxamide; /V-[4,6-dichloro-2-[(di-2-propyl-lambda-4-sulfanylidene)carb a- moyl]-phenyl]-2-(3-chloro-2-pyridyl)-5-(trifluoromethyl)pyra zole-3-carboxamide; /V-[4,6-dibro- mo-2-[(diethyl-lambda-4-sulfanylidene)carbamoyl]-phenyl]-2-( 3-chloro-2-pyridyl)-5-(trifluoro- methyl)pyrazole-3-carboxamide; /V-[2-(5-amino-1 ,3,4-thiadiazol-2-yl)-4-chloro-6-methylphe- nyl]-3-bromo-1 -(3-chloro-2-pyridinyl)-1 A pyrazole-S-carboxamide; 3-chloro-1 -(3-chloro-2-py- ridinyl)-/V-[2,4-dichloro-6-[[(1 -cyano-1 -methylethyl)amino]carbonyl]phenyl]-1 A pyrazole-

5-carboxamide; 3-bromo-/V-[2,4-dichloro-6-(methylcarbamoyl)phenyl]-1-(3,5-d ichloro-2-pyri- dyl)-1 A pyrazole-S-carboxamide; /V-[4-chloro-2-[[(1 ,1-dimethylethyl)amino]carbonyl]-6-meth- ylphenyl]-1 -(3-chloro-2-pyridinyl)-3-(fluoromethoxy)-1 A pyrazole-S-carboxamide; cyhalodi- amide;

0.27: Chordotonal organ Modulators - undefined target site: flonicamid;

0.28. insecticidal active compounds of unknown or uncertain mode of action: afidopyropen, afoxolaner, azadirachtin, amidoflumet, benzoximate, broflanilide, bromopropylate, chino- methionat, cryolite, dicloromezotiaz, dicofol, flufenerim, flometoquin, fluensulfone, fluhexafon, fluopyram, fluralaner, metoxadiazone, piperonyl butoxide, pyflubumide, pyridalyl, tioxazafen,

1 1-(4-chloro-2,6-dimethylphenyl)-12-hydroxy-1 ,4-dioxa-9-azadispiro[4.2.4.2]-tetradec-11-en- 10-one, 3-(4’-fluoro-2,4-dimethylbiphenyl-3-yl)-4-hydroxy-8-oxa-1 -azaspiro[4.5]dec-3-en- 2-one, 1-[2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]pheny l]-3-(trifluoromethyl)- 1 H-L ,2,4-triazole-5-amine, Bacillus firm us ^582 flupyrimin; fluazaindolizine; 4-[5-(3,5-di- chlorophenyl)-5-(trifluoromethyl)-4 T ^L isoxazol-3-yl]-2-methyl-/V-(1-oxothietan-3-yl)benzamid e; fluxametamide; 5-[3-[2,6-dichloro-4-(3,3-dichloroallyloxy)phenoxy]propoxy]- 1 A pyrazole;

4-cyano-/V-[2-cyano-5-[[2,6-dibromo-4-[1 ,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phen- yl]carbamoyl]phenyl]-2-methyl-benzamide; 4-cyano-3-[(4-cyano-2-methyl-benzoyl)amino]- /V-[2,6-dichloro-4-[1 ,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]-2-fl uoro-benz- amide; /V-[5-[[2-chloro-6-cyano-4-[1 ,2,2,3,3,3-hexafluoro-1 -(trifluoromethyl)propyl]phenyl]- carbamoyl]-2-cyano-phenyl]-4-cyano-2-methyl-benzamide; /V-[5-[[2-bromo-6-chloro-

4-[2, 2, 2-trifluoro-1 -hydroxy-1 -(trifluoromethyl)ethyl]phenyl]carbamoyl]-2-cyano-phenyl]-4- cy- ano-2-methyl-benzamide; /V-[5-[[2-bromo-6-chloro-4-[1 ,2,2,3,3,3-hexafluoro-1 -(trifluoro- methyl)propyl]phenyl]carbamoyl]-2-cyano-phenyl]-4-cyano-2-me thyl-benzamide; 4-cyano- /V-[2-cyano-5-[[2,6-dichloro-4-[1 ,2,2,3,3,3-hexafluoro-1-(trifluoromethyl)propyl]phenyl]carba - moyl]phenyl]-2-methyl-benzamide; 4-cyano-/V-[2-cyano-5-[[2,6-dichloro-4-[1 ,2,2,2-tetrafluoro-

1-(trifluoromethyl)ethyl]phenyl]carbamoyl]phenyl]-2-methy l-benzamide; /V-[5-[[2-bromo-

6-chloro-4-[1 ,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]carbamoyl ]-2-cyano-phenyl]-

4-cyano-2-methyl-benzamide; 2-(1 ,3-dioxan-2-yl)-6-[2-(3-pyridinyl)-5-thiazolyl]-pyridine;

2-[6-[2-(5-fluoro-3-pyridinyl)-5-thiazolyl]-2-pyridinyl]- pyrimidine; 2-[6-[2-(3-pyridinyl)-5-thi- azolyl]-2-pyridinyl]-pyrimidine; /V-methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-ca r- boxamide; /V-methylsulfonyl-6-[2-(3-pyridyl)thiazol-5-yl]pyridine-2-ca rboxamide; 1 -[(6-chloro-

3-pyridinyl)methyl]-1 ,2,3,5,6,7-hexahydro-5-methoxy-7-methyl-8-nitro-imidazo[1 ,2-a]pyridine; 1-[(6-chloropyridin-3-yl)methyl]-7-methyl-8-nitro-1 ,2,3,5,6,7-hexahydroimidazo[1 ,2-a]pyridin-

5-ol; 1-isopropyl-/V,5-dimethyl-/V-pyridazin-4-yl-pyrazole-4-carbo xamide; 1-(1 ,2-dimethyl- propyl)-/V-ethyl-5-methyl-/V-pyridazin-4-yl-pyrazole-4-carbo xamide; /V,5-dimethyl-/V-pyridazin- 4-yl-1 -(2,2,2-trifluoro-1 -methyl-ethyl)pyrazole-4-carboxamide; 1 -[1 -(1 -cyanocyclopropyl)eth- yl]-/V-ethyl-5-methyl-/V-pyridazin-4-yl-pyrazole-4-carboxami de; /V-ethyl-1 -(2-fluoro-1 -methyl- propyl)-5-meth-yl-/V-pyridazin-4-yl-pyrazole-4-carboxamide; 1 -(1 ,2-dimethylpropyl)-/V,5-di- methyl-/V-pyridazin-4-yl-pyrazole-4-carboxamide; 1 -[1 -(1 -cyanocyclopropyl)ethyl]-/V,5-di- methyl-/V-pyridazin-4-yl-pyrazole-4-carboxamide; /V-methyl-1 -(2-fluoro-1 -methyl-propyl]-

5-methyl-/V-pyridazin-4-yl-pyrazole-4-carboxamide; 1-(4,4-difluorocyclohexyl)-/V-ethyl- 5-methyl-/V-pyridazin-4-yl-pyrazole-4-carboxamide; 1-(4,4-difluorocyclohexyl)-/V,5-dimethyl- /V-pyridazin-4-yl-pyrazole-4-carboxamide, /V-(1-methylethyl)-2-(3-pyridinyl)-2 T ^L indazole-

4-carboxamide; /V-cyclopropyl-2-(3-pyndinyl)-2 T ^L indazole-4-carboxamide; /V-cyclohexyl- 2-(3-pyridinyl)-2A ^L indazole-4-carboxamide; 2-(3-pyridinyl)-/V-(2,2,2-trifluoroethyl)-2A ^L inda- zole-4-carboxamide; 2-(3-pyridinyl)-/V-[(tetrahydro-2-furanyl)methyl]-2A ^L indazole-5-carbox- amide; methyl 2-[[2-(3-pyridinyl)-2A ^L indazol-5-yl]carbonyl]hydrazinecarboxylate; LA[( 2,2-di- fluorocyclopropyl)methyl]-2-(3-pyridinyl)-2/7-indazole-5-car boxamide; /V-(2,2-difluoropropyl)-

2-(3-pyridinyl)-2A ^L indazole-5-carboxamide; 2-(3-pyridinyl )-/V-(2-pyrimidinylmethyl )-2H-\n- dazole-5-carboxamide; /V-[(5-methyl-2-pyrazinyl)methyl]-2-(3-pyridinyl)-2AT ^L indazole-5-car- boxamide, tyclopyrazoflor; sarolaner, lotilaner, /V-[4-chloro-3-[[(phenylmethyl)amino]car- bonyl]phenyl]-1-methyl-3-(1 ,1 ,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)-1 /7-pyrazole-5-car- boxamide; M. UN.22a 2-(3-ethylsulfonyl-2-pyridyl)-3-methyl-6-(trifluoromethyl)im id- azo[4,5-b]pyridine, 2-[3-ethylsulfonyl-5-(trifluoromethyl)-2-pyridyl]-3-methyl-6 -(trifluoro- methyl)imidazo[4,5-b]pyridine, 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4A ^L isoxazol-3-yl]- /V-[(4/\ -2-ethyl-3-oxo-isoxazolidin-4-yl]-2-methyl-benzamide, 4-[5-(3,5-dichloro-4-fluoro- phenyl)-5-(trifluoromethyl)-4 7 ^L isoxazol-3-yl]-/V-[(4/^-2-ethyl-3-oxo-isoxazolidin-4-y l]-2-meth- yl-benzamide; /V-[4-chloro-3-(cyclopropylcarbamoyl)phenyl]-2-methyl-5-(1 ,1 ,2,2,2-penta- fluoroethyl)-4-(trifluoromethyl)pyrazole-3-carboxamide, /V-[4-chloro-3-[(1-cyanocyclopropyl)- carbamoyl]phenyl]-2-methyl-5-(1 , 1 ,2,2, 2-pentafluoroethyl)-4-(trifluoromethyl)pyrazole-

3-carboxamide; acynonapyr; benzpyrimoxan; chloro-/V-(1-cyanocyclopropyl)-5-[1-[2-methyl-

5-(1 ,1 ,2,2,2-pentafluoroethyl)-4-(trifluoromethyl)pyrazol-3-yl]pyr azol-4-yl]benzamide, oxazo- sulfyl, [(25,3/?,4/?,55,6S)-3,5-dimethoxy-6-methyl-4-propoxy-tetrahy dropyran-2-yl]- /V-[4-[1-[4-(trifluoromethoxy)phenyl]-1 ,2,4-triazol-3-yl]phenyl]carbamate,

[(25,3/?,4/?,55,6S)-3,4,5-trimethoxy-6-methyl-tetrahydropyra n-2-yl] N-[4-[1-[4-(trifluoro- methoxy)phenyl]-1 ,2,4-triazol-3-yl]phenyl]carbamate, [(25,3/?,4/?,55,6S)-3,5-dimethoxy-

6-methyl-4-propoxy-tetrahydropyran-2-yl]-/V-[4-[1-[4-(1 ,1 ,2,2,2-pentafluoroethoxy)phenyl]-

1.2.4-triazol-3-yl]phenyl]carbamate, [(25,3/?,4/?,55,6S)-3,4,5-trimethoxy-6-methyl-tetra- hydropyran-2-yl]-/V-[4-[1-[4-(1 ,1 ,2,2,2-pentafluoroethoxy)phenyl]-1 ,2,4-triazol-3-yl]phenyl]- carbamate, (22)-3-(2-isopropylphenyl)-2-[(£)-[4-[1-[4-(1 ,1 ,2,2,2-pentafluoroethoxy)phenyl]-

1.2.4-triazol-3-yl]phenyl]methylenehydrazono]thiazolidin- 4-one.

a

The above active substances, their preparation and their activity e. g. against harmful fungi is known (cf.: http://www.alanwood.net/pesticides/); these substances are commercially available. The compounds described by IUPAC nomenclature, their preparation and their pesticidal activi- ty are also known (cf. Can. J. Plant Sci. 48(6), 587-94, 1968; EP-A 141 317; EP-A 152 031 ; EP- A 226 917; EP-A 243 970; EP-A 256 503; EP-A 428 941 ; EP-A 532 022; EP-A 1 028 125; EP-A 1 035 122; EP-A 1 201 648; EP-A 1 122 244, JP 2002316902; DE 19650197; DE 10021412; DE 102005009458; US 3,296,272; US 3,325,503; WO 98/46608; WO 99/14187; WO 99/24413;

WO 99/27783; WO 00/29404; WO 00/46148; WO 00/65913; WO 01/54501 ; WO 01/56358;

WO 02/22583; WO 02/40431 ; WO 03/10149; WO 03/11853; WO 03/14103; WO 03/16286;

WO 03/53145; WO 03/61388; WO 03/66609; WO 03/74491 ; WO 04/49804; WO 04/83193;

WO 05/120234; WO 05/123689; WO 05/123690; WO 05/63721 ; WO 05/87772; WO 05/87773; WO 06/15866; WO 06/87325; WO 06/87343; WO 07/82098; WO 07/90624, WO 10/139271 ,

WO 11/028657, WO 12/168188, WO 07/006670, WO 1 1/77514; WO 13/047749, WO

10/069882, WO 13/047441 , WO 03/16303, WO 09/90181 , WO 13/007767, WO 13/010862,

WO 13/127704, WO 13/024009, WO 13/24010, WO 13/047441 , WO 13/162072,

WO 13/092224, WO 11/135833, CN 1907024, CN 1456054, CN 103387541 , CN 1309897,

WO 12/84812, CN 1907024, WO 09094442, WO 14/60177, WO 13/116251 , WO 08/013622, WO 15/65922, WO 94/01546, EP 2865265, WO 07/129454, WO 12/16551 1 , WO 1 1/081 174, WO 13/47441). Some compounds are identified by their CAS Registry Number which is sepa- rated by hyphens into three parts, the first consisting from two up to seven digits, the second consisting of two digits, and the third consisting of a single digit.

The compositions according to the present invention are distinguished by an outstanding effec- tiveness against a broad spectrum of phytopathogenic fungi, including soil-borne fungi, which derive especially from the classes of the Plasmodiophoromycetes, Peronosporomycetes (syn. Oomycetes), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes, and Deuteromy- cetes (syn. Fungi imperfecti). Some are systemically effective and they can be used in crop pro- tection as foliar fungicides, fungicides for seed dressing, and soil fungicides. Moreover, they are suitable for controlling harmful fungi, which inter alia occur in wood or roots of plants.

The compositions according to the present invention are particularly important in the control of a multitude of phytopathogenic fungi on various cultivated plants, such as cereals, e. g. wheat, rye, barley, triticale, oats, or rice; beet, e. g. sugar beet or fodder beet; fruits, e. g. pomes (ap- ples, pears, etc.), stone fruits (plums, peaches, almonds, cherries, etc.), or soft fruits, which are also called berries (strawberries, raspberries, blackberries, gooseberries, etc.); leguminous plants, e. g. lentils, peas, alfalfa, or soybeans; oil plants, e. g. rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts, or soybeans; cucurbits, e. g. squashes, cucumber, or melons; fiber plants, e. g. cotton, flax, hemp, or jute; citrus fruits, e. g. oranges, lemons, grapefruits, or mandarins; vegetables, e. g. spinach, lettuce, asparagus, cab- bages, carrots, onions, tomatoes, potatoes, cucurbits, or paprika; lauraceous plants, e. g. avo- cados, cinnamon, or camphor; energy and raw material plants, e. g. corn, soybean, rape, sugar cane, or oil palm; corn; tobacco; nuts; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; turf; sweet leaf (also called Stevia); natural rubber plants; or ornamental and forestry plants, e. g. flowers, shrubs, broad-leaved trees, or evergreens (conifers, eucalypts, etc.); and on the plant propagation material, such as seeds; and on the crop material of these plants.

Preferably, the compositions according to the present invention are used for controlling a multi- tude of fungi on field crops, such as potatoes, sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rape, legumes, sunflowers, coffee or sugar cane; fruits; vines; or- namentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.

In further preferred embodiment, the inventive compositions are used for controlling fungal dis eases of cereals, such as wheat, rye or barley.

The inventive compositions are employed by treating the fungi, or the plants, plant propagation materials (preferably seeds), materials or soil to be protected from fungal attack with a fungicidal effective amount of the active compounds. The application can be carried out both before and after the infection of the materials, plants or plant propagation materials (preferably seeds) by the fungi.

Plant propagation materials may be treated with compositions according to the present inven- tion prophylactically either at or before planting or transplanting.

The term "cultivated plants" is to be understood as including plants which have been modified by mutagenesis or genetic engineering to provide a new trait to a plant or to modify an already present trait. Mutagenesis includes techniques of random mutagenesis using X-rays or muta- genic chemicals, but also techniques of targeted mutagenesis, to create mutations at a specific locus of a plant genome. Targeted mutagenesis techniques frequently use oligonucleotides or proteins like CRISPR/Cas, zinc-finger nucleases, TALENs or meganucleases to achieve the targeting effect. Genetic engineering usually uses recombinant DNA techniques to create modi- fications in a plant genome which under natural circumstances cannot readily be obtained by cross breeding, mutagenesis or natural recombination. Typically, one or more genes are inte- grated into the genome of a plant to add a trait or improve a trait. These integrated genes are also referred to as transgenes in the art, while plant comprising such transgenes are referred to as transgenic plants. The process of plant transformation usually produces several transfor- mation events, which differ in the genomic locus in which a transgene has been integrated. Plants comprising a specific transgene on a specific genomic locus are usually described as comprising a specific“event”, which is referred to by a specific event name. Traits which have been introduced in plants or have been modified include herbicide tolerance, insect resistance, increased yield and tolerance to abiotic conditions, like drought.

Herbicide tolerance has been created by using mutagenesis as well as using genetic engi- neering. Plants which have been rendered tolerant to acetolactate synthase (ALS) inhibitor herbicides by mutagenesis and breeding comprise plant varieties commercially available under the name Clearfield®.

Herbicide tolerance has been created via the use of transgenes to glyphosate, glufosinate, 2,4-D, dicamba, oxynil herbicides, like bromoxynil and ioxynil, sulfonylurea herbicides, ALS in- hibitors and 4-hydroxyphenyl pyruvate dioxygenase (HPPD) inhibitors, like isoxaflutole and mesotrione.

Transgenes which have been used to provide herbicide tolerance traits comprise: for toler- ance to glyphosate: cp4 epsps, epsps grg23ace5, mepsps, 2mepsps, gat4601 , gat4621 , goxv247; for tolerance to glufosinate: pat and bar, for tolerance to 2,4-D: aad-1 , aad-12; for tol erance to dicamba: dmo; for tolerance to oxynil herbicies: bxn; for tolerance to sulfonylurea herbicides: zm-hra, csr1-2, gm-hra, S4-HrA; for tolerance to ALS inhibitors: csr1-2; and for tol- erance to HPPD inhibitors: hppdPF, W336, avhppd-03.

Transgenic corn events comprising herbicide tolerance genes include, but are not limited to, DAS40278, MON801 , MON802, MON809, MON810, MON832, MON8741 1 , MON87419, MON87427, MON88017, MON89034, NK603, GA21 , MZHG0JG, HCEM485, VCO-01981-5, 676, 678, 680, 33121 , 4114, 59122, 98140, Bt10, Bt176, CBH-351 , DBT418, DLL25, MS3,

MS6, MZIR098, T25, TC1507 and TC6275. Transgenic soybean events comprising herbicide tolerance genes include, but are not limited to, GTS 40-3-2, MON87705, MON87708,

MON87712, MON87769, MON89788, A2704-12, A2704-21 , A5547-127, A5547-35, DP356043, DAS44406-6, DAS68416-4, DAS-81419-2, GU262, SYHT0H2, W62, W98, FG72 and CV127. Transgenic cotton events comprising herbicide tolerance genes include, but are not limited to, 19-51 a, 31707, 42317, 81910, 281-24-236, 3006-210-23, BXN1021 1 , BXN10215, BXN10222, BXN10224, MON1445, MON1698, MON88701 , MON88913, GHB119, GHB614, LLCotton25, T303-3 and T304-40. Transgenic canola events comprising herbicide tolerance genes are for example, but not excluding others, MON88302, HCR-1 , HCN10, HCN28, HCN92, MS1 , MS8, PHY14, PHY23, PHY35, PHY36, RF1 , RF2 and RF3.

Insect resistance has mainly been created by transferring bacterial genes for insecticidal proteins to plants: Transgenes which have most frequently been used are toxin genes of Bacil lus spp. and synthetic variants thereof, like cry1A, crylAb, cry1Ab-Ac, crylAc, cry1A.105, cry1 F, cry1 Fa2, cry2Ab2, cry2Ae, mcry3A, ecry3.1Ab, cry3Bb1 , cry34Ab1 , cry35Ab1 , cry9C, vip3A(a), vip3Aa20. However, also genes of plant origin, such as genes coding for protease inhibitors, like CpTI and pinll, have been transferred to other plants. A further approach uses transgenes such as dvsnf7 to produce double-stranded RNA in plants.

Transgenic corn events comprising genes for insecticidal proteins or double stranded RNA include, but are not limited to, Bt10, Bt1 1 , Bt176, MON801 , MON802, MON809, MON810, MON863, MON87411 , MON88017, MON89034, 33121 , 41 14, 5307, 59122, TC1507, TC6275, CBH-351 , MIR162, DBT418 and MZIR098. Transgenic soybean events comprising genes for insecticidal proteins include, but are not limited to, MON87701 , MON87751 and DAS-81419. Transgenic cotton events comprising genes for insecticidal proteins include, but are not limited to, SGK321 , MON531 , MON757, MON1076, MON15985, 31707, 31803, 31807, 31808, 42317, BN LA-601 , Eventl , COT67B, COT102, T303-3, T304-40, GFM Cry1A, GK12, MLS 9124, 281- 24-236, 3006-210-23, GHB119 and SGK321.

Increased yield has been created by using the transgene athb17, being present for example in corn event MON87403, or by using the transgene bbx32, being present for example in the soybean event MON87712.

Cultivated plants comprising a modified oil content have been created by using the transgenes: gm-fad2-1 , Pj.D6D, Nc.Fad3, fad2-1A and fatb1-A. Soybean events comprising at least one of these genes are: 260-05, MON87705 and MON87769.

Tolerance to abiotic conditions, such as drought, has been created by using the transgene cspB, comprised by the corn event MON87460 and by using the transgene Hahb-4, comprised by soybean event IND-00410-5.

Traits are frequently combined by combining genes in a transformation event or by combin- ing different events during the breeding process resulting in a cultivated plant with stacked traits. Preferred combinations of traits are combinations of herbicide tolerance traits to different groups of herbicides, combinations of insect tolerance to different kind of insects, in particular tolerance to lepidopteran and coleopteran insects, combinations of herbicide tolerance with one or several types of insect resistance, combinations of herbicide tolerance with increased yield as well as combinations of herbicide tolerance and tolerance to abiotic conditions.

Plants comprising singular or stacked traits as well as the genes and events providing these traits are well known in the art. For example, detailed information as to the mutagenized or inte- grated genes and the respective events are available from websites of the organizations“Inter- national Service for the Acquisition of Agri-biotech Applications (ISAAA)”

(http://www.isaaa.org/gmapprovaldatabase) and the“Center for Environmental Risk Assess- ment (CERA)” (http://cera-gmc.org/GMCropDatabase). Further information on specific events and methods to detect them can be found for canola events MS1 , MS8, RF3, GT73,

MON88302, KK179 in W001/031042, W001/041558, W001/041558, W002/036831 ,

W01 1/153186, W013/003558, for cotton events MON 1445, MON 15985, MON531

(MON 15985), LLCotton25, MON88913, COT102, 281-24-236, 3006-210-23, COT67B,

GHB614, T304-40, GHB119, MON88701 , 81910 in WO02/034946, W002/100163,

W002/100163, WO03/013224, WO04/072235, WO04/039986, WO05/103266, WO05/103266, WO06/128573, W007/017186, WO08/122406, W008/151780, W012/134808, W013/1 12527; for corn events GA21 , MON810, DLL25, TC1507, MON863, MIR604, LY038, MON88017, 3272, 59122, NK603, MIR162, MON89034, 98140, 32138, MON87460, 5307, 4114, MON87427, DAS40278, MON87411 , 33121 , MON87403, MON87419 in W098/044140, US02/102582, US03/126634, WO04/099447, WO04/01 1601 , WO05/103301 , W005/061720, W005/059103, WO06/098952, WO06/039376, US2007/292854, WO07/142840, WO07/140256,

WO08/112019, WO09/103049, WO09/1 11263, W010/077816, W011/084621 , W011/062904, W01 1/022469, W013/169923, W014/1 16854, W015/053998, W015/142571 ; for potato events E12, F10, J3, J55, V1 1 , X17, Y9 in WO14/178910, W014/178913, W014/178941 ,

W014/179276, W016/183445, W017/062831 , W017/062825; for rice events LLRICE06, LLRICE601 , LLRICE62 in WO00/026345, WO00/026356, WO00/026345; and for soybean events H7-1 , MON89788, A2704-12, A5547-127, DP305423, DP356043, MON87701 ,

MON87769, CV127, MON87705, DAS68416-4, MON87708, MON87712, SYHT0H2,

DAS81419, DAS81419 x DAS44406-6, MON87751 in WO04/074492, W006/130436,

WO06/108674, WO06/108675, WO08/054747, W008/002872, WO09/064652, WO09/102873, W010/080829, W010/037016, W01 1/066384, W01 1/034704, WO12/051 199, WO12/082548, W013/016527, WO13/016516, W014/201235.

The use of compositions according to the invention, respectively, on cultivated plants may result in effects which are specific to a cultivated plant comprising a certain gene or event.

These effects might involve changes in growth behavior or changed resistance to biotic or abiot- ic stress factors. Such effects may in particular comprise enhanced yield, enhanced resistance or tolerance to insects, nematodes, fungal, bacterial, mycoplasma, viral or viroid pathogens as well as early vigour, early or delayed ripening, cold or heat tolerance as well as changed amino acid or fatty acid spectrum or content.

The compositions according to the present invention are particularly suitable for controlling the following plant diseases:

Albugo spp. (white rust) on ornamentals, vegetables (e. g. A. Candida) and sunflowers (e. g. A. tragopogonis), A Hern aria spp. (Alternaria leaf spot) on vegetables, rape {A. brassicoia or brass/- cae), sugar beets (A tenuis), fruits, rice, soybeans, potatoes (e. g. A so la ni or A. a/ternata), tomatoes (e. g. A. sotani or A. a/ternata) and wheat; Aphanomyces spp. on sugar beets and vegetables; Ascochyta spp. on cereals and vegetables, e. g. A. r/f/c/ (anthracnose) on wheat and A. horde ion barley; Bipoiaris and Drechsiera spp. (teleomorph: Cochiioboius spp.), e. g. Southern leaf blight ( D . maydis) or Northern leaf blight (B. zeicoia) on corn, e. g. spot blotch (B. sorokiniana) on cereals and e. g. B. oryzae on rice and turfs; Biumeria (formerly Erysiphe) graminis (powdery mildew) on cereals (e. g. on wheat or barley); Botrytis cinerea (teleomorph: Botryotinia fuckeiiana. grey mold) on fruits and berries (e. g. strawberries), vegetables (e. g. lettuce, carrots, celery and cabbages), rape, flowers, vines, forestry plants and wheat; Bremia iactucae (downy mildew) on lettuce; Ceratocystis { syn. Ophiostoma) spp. (rot or wilt) on broad- leaved trees and evergreens, e. g. C. u im i (Dutch elm disease) on elms; Cercospora spp. (Cer- cospora leaf spots) on corn (e. g. Gray leaf spot: C. zeae-maydis), rice, sugar beets (e. g. C. beticoia), sugar cane, vegetables, coffee, soybeans (e. g. C. sojina or C. kikuchh ) and rice; Ciadosporium spp. on tomatoes (e. g. C. fuivurrr. leaf mold) and cereals, e. g. C. herbarum (black ear) on wheat; Ciaviceps purpurea (ergot) on cereals; Cochiioboius (anamorph: Heimin- thosporium of Bipoiaris) spp. (leaf spots) on corn {C. carbonum), cereals (e. g. C. sativus, ana- morph: B. sorokiniana) and rice (e. g. C. miyabeanus, anamorph: H. oryzae), Coiietotrichum (teleomorph: Giomereiia) spp. (anthracnose) on cotton (e. g. C. gossypii), corn (e. g. C. gramini- co/a; Anthracnose stalk rot), soft fruits, potatoes (e. g. C. coccodes. black dot), beans (e. g. C. iindemuthianum) and soybeans (e. g. C. truncatum or C. gioeosporioides), Corticium spp., e. g. C. sasakii (sheath blight) on rice; Corynespora cassiicoia (leaf spots) on soybeans and orna- mentals; Cycioconium spp., e. g. C. oieaginum on olive trees; Cyiindrocarpon spp. (e. g. fruit tree canker or young vine decline, teleomorph: Nectria or Neonectria spp.) on fruit trees, vines (e. g. C. iiriodendri, teleomorph: Neonectria iiriodendri Black Foot Disease) and ornamentals; Dematophora (teleomorph: Roseiiinia) necatrix (root and stem rot) on soybeans; Diaporthe spp., e. g. D. phaseoiorum (damping off) on soybeans; Drechsiera (syn. Heiminthosporium, teleo- morph: Pyrenophora) spp. on corn, cereals, such as barley (e. g. D. teres, net blotch) and wheat (e. g. D. tritici-repentis. tan spot), rice and turf; Esca (dieback, apoplexy) on vines, caused by Formitiporia (syn. Pheiiinus) punctata, F. mediterranea, Phaeomonieiia chiamydospora (earlier Phaeoacremonium chiamydosporum), Phaeoacremonium aieophiium and/or Botryosphaeria obtusa, E/sinoe spp. on pome fruits (F. pyri), soft fruits ( E . veneta. anthracnose) and vines {E. ampeiina anthracnose); Entyioma oryzae (leaf smut) on rice; Epicoccum spp. (black mold) on wheat; Erysiphe spp. (powdery mildew) on sugar beets ( E . betae), vegetables (e. g. E. pisi), such as cucurbits (e. g. E. cichoracearum), cabbages, rape (e. g. E. cruciferarum)·, Eutypa iata (Eutypa canker or dieback, anamorph: Cytosporina iata, syn. Liberteiia biepharis) on fruit trees, vines and ornamental woods; Exserohiium (syn. Heiminthosporium) spp. on corn (e. g. E. turci- cum)\ Fusarium (teleomorph: Gibbereiia) spp. (wilt, root or stem rot) on various plants, such as F. graminearum or F. cuimorum (root rot, scab or head blight) on cereals (e. g. wheat or barley), F. oxysporum on tomatoes, F. soiani (f . sp. glycines now syn. F. virguiiforme ) and F. tucumani- ae and F. brasiiiense each causing sudden death syndrome on soybeans, and F. verticiiiioides on corn; Gaeumannomyces graminis (take-all) on cereals (e. g. wheat or barley) and corn; Gib- bereiia spp. on cereals (e. g. G. zeae) and rice (e. g. G. fujikuroi. Bakanae disease); Giomereiia cinguiata on vines, pome fruits and other plants and G. gossypii on cotton; Grainstaining com- plex on rice; Guignardia bidweiiii (black rot) on vines; Gymnosporangium spp. on rosaceous plants and junipers, e. g. G. sabinae (rust) on pears; Helminthosporium spp. (syn. Drechslera, teleomorph: Cochiioboius ) on corn, cereals and rice; Hemileia spp., e. g. H. vastatrix (coffee leaf rust) on coffee; /sariopsis davispora (syn. Ciadosporium vitis) on vines; Macrophomina phaseolina (syn. phaseoh ) (root and stem rot) on soybeans and cotton; Microdochium (syn. Fusarium) nivale (pink snow mold) on cereals (e. g. wheat or barley); Microsphaera diffusa (powdery mildew) on soybeans; MoniUnia spp., e. g. M. laxa, M. fructico/a and M. fructigena (bloom and twig blight, brown rot) on stone fruits and other rosaceous plants; Mycosphaerella spp. on cereals, bananas, soft fruits and ground nuts, such as e. g. M. graminico/a (anamorph: Septoria tritici, Septoria blotch) on wheat or M. fijiensis (black Sigatoka disease) on bananas; Peronospora spp. (downy mildew) on cabbage (e. g. P. brassicae ), rape (e. g. P. parasitica), onions (e. g. P. destructor ), tobacco {P. tabacina) and soybeans (e. g. P. manshurica );

Phakopsora pachyrhizi and P. meibomiae (soybean rust) on soybeans; Phiaiophora spp. e. g. on vines (e. g. P. tracheiphiia and P. tetraspora) and soybeans (e. g. P. gregata. stem rot); Phoma iingam (root and stem rot) on rape and cabbage and P. betae (root rot, leaf spot and damping-off) on sugar beets; Phomopsis s . on sunflowers, vines (e. g. P. viticoia. can and leaf spot) and soybeans (e. g. stem rot: P. phaseoii, teleomorph: Diaporthe phaseoiorum) Phy- soderma maydis (brown spots) on corn; Phytophthora spp. (wilt, root, leaf, fruit and stem root) on various plants, such as paprika and cucurbits (e. g. P. capsici), soybeans (e. g. P.

megasperma, syn. P. sojae), potatoes and tomatoes (e. g. P. infestans. late blight) and broad- leaved trees (e. g. P. ramorum. sudden oak death); Piasmodiophora brassicae (club root) on cabbage, rape, radish and other plants; Piasmopara s ., e. g. P. viticoia (grapevine downy mildew) on vines and P. haistedii on sunflowers; Podosphaera spp. (powdery mildew) on rosa- ceous plants, hop, pome and soft fruits, e. g. P. ieucotricha on apples; Poiymyxa s ., e. g. on cereals, such as barley and wheat ( P graminis) and sugar beets ( P betae) and thereby trans- mitted viral diseases; Pseudocercosporeiia herpotrichoides {e yespot, teleomorph: Tapesia yai- iundae) on cereals, e. g. wheat or barley; Pseudoperonospora (downy mildew) on various plants, e. g. P. cube ns is on cucurbits or P. humiii on hop; Pseudopezicuia tracheiphiia (red fire disease or .rotbrenner’, anamorph: Phiaiophora) on vines; Puccinia s . (rusts) on various plants, e. g. P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei (dwarf rust), P. graminis (stem or black rust) or P. recondite (brown or leaf rust) on cereals, such as e. g. wheat, barley or rye, P. kuehnii (orange rust) on sugar cane and P. asparagi on asparagus; Pyrenophora (anamorph: Drechslera) tritici-repentis (tan spot) on wheat or P. teres (net blotch) on barley; Pyricuiaria spp., e. g. P. oryzae (teleomorph: Magnaporthe grisea, rice blast) on rice and P. grisea on turf and cereals; Pythium s . (damping-off) on turf, rice, corn, wheat, cotton, rape, sunflowers, soybeans, sugar beets, vegetables and various other plants (e. g. P. uitimum or P. aphanidermatum) Ramuiaria spp., e. g. R. coiio-cygni ( Ra m u I a ri a leaf spots, Physiological leaf spots) on barley and R. beticoia on sugar beets; Rhizoctonia spp. on cotton, rice, potatoes, turf, corn, rape, potatoes, sugar beets, vegetables and various other plants, e. g. R. soiani {rooi and stem rot) on soybeans, R. soiani (sheath blight) on rice or R. cereaiis (Rhizoctonia spring blight) on wheat or barley; Rhizopus stoionifer (black mold, soft rot) on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium seca/is (scald) on barley, rye and triticale; Sa- rociadium oryzae and S. attenuatum (sheath rot) on rice; Scierotinia spp. (stem rot or white mold) on vegetables and field crops, such as rape, sunflowers (e. g. S. scierotiorum) and soy- beans (e. g. S. roifsii or S. scierotiorum)·, Septoria spp. on various plants, e. g. S. glycines (brown spot) on soybeans, S. tritici (Septoria blotch) on wheat and S. (syn. Stagonospora ) no- dorum (Stagonospora blotch) on cereals; Uncinula (syn. Erysiphe) necator (powdery mildew, anamorph: Oidium tucker!) on vines; Setospaeria spp. (leaf blight) on corn (e. g. S. turcicum, syn. He!minthosporium turcicum) and turf; Sphace!otheca spp. (smut) on corn, (e. g. S. reiHana. head smut), sorghum und sugar cane; Sphaerotheca futiginea (powdery mildew) on cucurbits; Spongospora subterranea (powdery scab) on potatoes and thereby transmitted viral diseases; Stagonospora s . on cereals, e. g. S. nodorum (Stagonospora blotch, teleomorph: Lepto- sphaeria [syn. Phaeosphaeria] nodorum) on wheat; Synchytrium endobioticum on potatoes (po- tato wart disease); Taphrina spp., e. g. T. deformans (leaf curl disease) on peaches and T. pruni (plum pocket) on plums; Thie/aviopsis spp. (black root rot) on tobacco, pome fruits, vegetables, soybeans and cotton, e. g. T. basicota (syn. Cha/ara eiegans), TiHetia spp. (common bunt or stinking smut) on cereals, such as e. g. T. tritici {s n. T. caries, wheat bunt) and T. controversa (dwarf bunt) on wheat; Typhuia incarnata (grey snow mold) on barley or wheat; Urocystis spp., e. g. U. occulta { stem smut) on rye; Uromyces spp. (rust) on vegetables, such as beans (e. g. U. appendicuiatus, syn. U. phaseoii) and sugar beets (e. g. U. betae) Ustiiago spp. (loose smut) on cereals (e. g. U. nuda an U. avaenae ), corn (e. g. Li. maydis. corn smut) and sugar cane; Venturia spp. (scab) on apples (e. g. V. inaequaiis) and pears; and Verticiiiium spp. (wilt) on various plants, such as fruits and ornamentals, vines, soft fruits, vegetables and field crops, e. g. 14 dahiiae on strawberries, rape, potatoes and tomatoes.

The compositions according to the present invention are also suitable for controlling harmful microorganisms in the protection of stored products or harvest, and in the protection of materi- als.

The term "stored products or harvest" is understood to denote natural substances of plant or animal origin and their processed forms, which have been taken from the natural life cycle and for which long-term protection is desired. Stored products of crop plant origin, such as plants or parts thereof, for example stalks, leaves, tubers, seeds, fruits or grains, can be protected in the freshly harvested state or in processed form, such as pre-dried, moistened, comminuted, ground, pressed or roasted, which process is also known as post-harvest treatment. Also falling under the definition of stored products is timber, whether in the form of crude timber, such as construction timber, electricity pylons and barriers, or in the form of finished articles, such as furniture or objects made from wood. Stored products of animal origin are hides, leather, furs, hairs and the like. Preferably, "stored products" is understood to denote natural substances of plant origin and their processed forms, more preferably fruits and their processed forms, such as pomes, stone fruits, soft fruits and citrus fruits and their processed forms. The compositions according the present invention can prevent disadvantageous effects such as decay, discolora- tion or mold.

The term "protection of materials" is to be understood to denote the protection of technical and non-living materials, such as adhesives, glues, wood, paper, paperboard, textiles, leather, paint dispersions, plastics, cooling lubricants, fiber, or fabrics; against the infestation and de- struction by harmful microorganisms, such as fungi and bacteria. As to the protection of materi- als, particular attention is paid to the following harmful fungi: Ascomycetes, such as Ophiostoma spp., Ceratocystis spp., Aureobasidium puiiuians, Scierophoma spp., Chaetomium spp., Humi- coia spp., Petrie Ha spp., Trichurus spp. Basidiomycetes, such as Coniophora spp., Corioius spp., Gioeophyiium spp., Lentinus spp., P/eurotus spp., Poria spp., Serpuia spp. and Tyromy- ces spp.; Deuteromycetes, such as Aspergillus spp., Cladosporium spp., PeniciHium spp., Trichoderma s p p . , Alternaria spp., PaecHomyces spp.; and Zygomycetes, such as Mucor spp..

In the protection of stored products and harvest in addition the following yeast fungi are worthy of note: Candida spp. and Saccharomyces cerevisae.

The compositions according to the present invention can be converted into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof. Examples for composition types are sus- pensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS,

DP, DS), pressings (e.g. BR, TB, DT), granules (e.g. WG, SG, GR, FG, GG, MG), as well as gel formulations for the treatment of plant propagation materials such as seeds (e.g. GF). These and further compositions types are defined in the“Catalogue of pesticide formulation types and international coding system”, Technical Monograph No. 2, 6 ^th Ed. May 2008, CropLife Interna- tional.

The compositions are prepared in a known manner, such as described by Mollet and Grube- mann, Formulation technology, Wiley VCH, Weinheim, 2001 ; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.

Suitable auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfactants, disper- sants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protective colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimulants, compatibil- izers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifiers and binders.

Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil frac- tions of medium to high boiling point, e.g. kerosene, diesel oil; oils of vegeable or animal origin; aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, al- kylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclohexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.

Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magne- sium sulfate, magnesium oxide; polysaccharides, e.g. cellulose, starch; fertilizers, e.g. ammoni- um sulfate, ammonium phosphate, ammonium nitrate, ureas; products of vegeable origin, e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.

Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emusifier, dispersant, solubilizer, wetter, penetration enhancer, protective col- loid, or adjuvant. Examples of surfactants are listed in McCutcheon’s, Vol.1 : Emulsifiers & De- tergents, McCutcheon’s Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).

Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sul- fates, phosphates, carboxylates, and mixtures thereof. Examples of sulfonates are alkylaryl- sulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alkylnaphthalenes, sulfosuccinates or sulfosuccinamates. Examples of sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethox- ylated alcohols, or of fatty acid esters. Examples of phosphates are phosphate esters. Exam- pies of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol ethoxylates.

Suitable nonionic surfactants are alkoxylates, N-subsituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof. Examples of alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents. Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide. Exam- pies of N-subsititued fatty acid amides are fatty acid glucamides or fatty acid alkanolamides. Examples of esters are fatty acid esters, glycerol esters or monoglycerides. Examples of sugar- based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or al- kylpolyglucosides. Examples of polymeric surfactants are home- or copolymers of vinylpyrroli- done, vinylalcohols, or vinylacetate.

Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines. Suitable amphoteric surfactants are alkylbetains and imidazolines. Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B-C type comprising alkanol, polyethylene oxide and polypropylene oxide. Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or pol- yethyleneamines.

Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the inventive mixtures on the tar- get. Examples are surfactants, mineral or vegeable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.

Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anor- ganic clays (organically modified or unmodified), polycarboxylates, and silicates.

Suitable bactericides are bronopol and isothiazolinone derivatives such as alkyliso- thiazolinones and benzisothiazolinones.

Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.

Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.

Suitable colorants (e.g. in red, blue, or green) are pigments of low water solubility and water- soluble dyes. Examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanofer- rate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).

Suitable tackifiers or binders are polyvinylpyrrolidons, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.

Examples for agrochemical composition types and their preparation are:

i) Water-soluble concentrates (SL, LS)

10-60 wt% of an inventive composition and 5-15 wt% wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) ad 100 wt%. The active substance dissolves upon dilution with water.

ii) Dispersible concentrates (DC)

5-25 wt% of an inventive composition and 1-10 wt% dispersant (e. g. polyvinylpyrrolidone) are dissolved in organic solvent (e.g. cyclohexanone) ad 100 wt%. Dilution with water gives a dispersion.

iii) Emulsifiable concentrates (EC)

15-70 wt% of an inventive composition and 5-10 wt% emulsifiers (e.g. calcium dodecylben- zenesulfonate and castor oil ethoxylate) are dissolved in water-insoluble organic solvent (e.g. aromatic hydrocarbon) ad 100 wt%. Dilution with water gives an emulsion.

iv) Emulsions (EW, EO, ES)

5-40 wt% of an inventive composition and 1-10 wt% emulsifiers (e.g. calcium dodecylben- zenesulfonate and castor oil ethoxylate) are dissolved in 20-40 wt% water-insoluble organic solvent (e.g. aromatic hydrocarbon). This mixture is introduced into water ad 100 wt% by means of an emulsifying machine and made into a homogeneous emulsion. Dilution with water gives an emulsion.

v) Suspensions (SC, OD, FS)

In an agitated ball mill, 20-60 wt% of an inventive composition are comminuted with addition of 2-10 wt% dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0.1-2 wt% thickener (e.g. xanthan gum) and water ad 100 wt% to give a fine active substance suspension. Dilution with water gives a stable suspension of the active substance. For FS type compositions up to 40 wt% binder (e.g. polyvinylalcohol) is added.

vi) Water-dispersible granules and water-soluble granules (WG, SG)

50-80 wt% of an inventive composition are ground finely with addition of dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) ad 100 wt% and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.

vii) Water-dispersible powders and water-soluble powders (WP, SP, WS)

50-80 wt% of an inventive composition are ground in a rotor-stator mill with addition of 1-5 wt% dispersants (e.g. sodium lignosulfonate), 1-3 wt% wetting agents (e.g. alcohol ethoxylate) and solid carrier (e.g. silica gel) ad 100 wt%. Dilution with water gives a stable dispersion or solution of the active substance.

viii) Gel (GW, GF)

In an agitated ball mill, 5-25 wt% of an inventive composition are comminuted with addition of 3-10 wt% dispersants (e.g. sodium lignosulfonate), 1-5 wt% thickener (e.g. carboxy- methylcellulose) and water ad 100 wt% to give a fine suspension of the active substance. Dilu tion with water gives a stable suspension of the active substance.

ix) Microemulsion (ME)

5-20 wt% of an inventive composition are added to 5-30 wt% organic solvent blend (e.g. fat- ty acid dimethylamide and cyclohexanone), 10-25 wt% surfactant blend (e.g. alcohol ethoxylate and arylphenol ethoxylate), and water ad 100 %. This mixture is stirred for 1 h to produce spon- taneously a thermodynamically stable microemulsion.

x) Microcapsules (CS) An oil phase comprising 5-50 wt% of an inventive composition, 0-40 wt% water insoluble organ- ic solvent (e.g. aromatic hydrocarbon), 2-15 wt% acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radical initiator results in the formation of poly(meth)acrylate microcapsules. Alternatively, an oil phase comprising 5-50 wt% of an inventive mixture according to the invention, 0-40 wt% water insoluble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylmethene-4,4’- diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl al- cohol). The addition of a polyamine (e.g. hexamethylenediamine) results in the formation of pol- yurea microcapsules. The monomers amount to 1-10 wt%. The wt% relate to the total CS corn- position.

xi) Dustable powders (DP, DS)

1-10 wt% of an inventive mixture are ground finely and mixed intimately with solid carrier (e.g. finely divided kaolin) ad 100 wt%.

xii) Granules (GR, FG)

0.5-30 wt% of an inventive mixture is ground finely and associated with solid carrier (e.g. sil icate) ad 100 wt%. Granulation is achieved by extrusion, spray-drying or fluidized bed.

xiii) Ultra-low volume liquids (UL)

1-50 wt% of an inventive mixture are dissolved in organic solvent (e.g. aromatic hydro- carbon) ad 100 wt%.

The compositions types i) to xi) may optionally comprise further auxiliaries, such as 0.1-1 wt% bactericides, 5-15 wt% anti-freezing agents, 0.1-1 wt% anti-foaming agents, and 0.1-1 wt% col- ora nts.

The resulting agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, in particular between 0.5 and 75%, by weight of active substances. The active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).

Solutions for seed treatment (LS), Suspoemulsions (SE), flowable concentrates (FS), powders for dry treatment (DS), water-dispersible powders for slurry treatment (WS), water-soluble pow- ders (SS), emulsions (ES), emulsifiable concentrates (EC) and gels (GF) are usually employed for the purposes of treatment of plant propagation materials, particularly seeds. The composi- tions in question give, after two-to-tenfold dilution, active substance concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40%, in the ready-to-use preparations. Application can be carried out before or during sowing. Methods for applying the inventive mixtures and compo- sitions thereof, respectively, on to plant propagation material, especially seeds include dressing, coating, pelleting, dusting, soaking and in-furrow application methods of the propagation mate- rial. Preferably, the inventive compositions are applied on to the plant propagation material by a method such that germination is not induced, e. g. by seed dressing, pelleting, coating and dust- ing.

When employed in plant protection, the amounts of active substances applied are, depend- ing on the kind of effect desired, from 0.001 to 2 kg per ha, preferably from 0.005 to 2 kg per ha, more preferably from 0.01 to 1.0 kg per ha, and in particular from 0.05 to 0.75 kg per ha. In treatment of plant propagation materials such as seeds, e. g. by dusting, coating or drenching seed, amounts of active substances of from 0.01-10kg, preferably from 0.1-1000 g, more preferably from 1-100 g per 100 kg of plant propagation material (preferably seeds) are generally required.

When used in the protection of materials or stored products, the amount of active substanc- es applied depends on the kind of application area and on the desired effect. Amounts custom- arily applied in the protection of materials are 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of ac- tive substances per cubic meter of treated material.

Various types of oils, wetters, adjuvants, fertilizer, or micronutrients, and further pesticides (e.g. herbicides, insecticides, fungicides, growth regulators, safeners) may be added to the ac- tive substances or the compositions comprising them as premix or, if appropriate not until im- mediately prior to use (tank mix). These agents can be admixed with the compositions accord- ing to the invention in a weight ratio of 1 :100 to 100:1 , preferably 1 :10 to 10:1.

The user applies the composition according to the invention usually from a predosage de- vice, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system. Usually, the ag- rochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.

According to one embodiment, individual components of the composition according to the in- vention such as parts of a kit or parts of a binary mixture may be mixed by the user himself in a spray tank or any other kind of vessel used for applications (e. g. seed treater drums, seed pel- leting machinery, knapsack sprayer) and further auxiliaries may be added, if appropriate.

Consequently, one embodiment of the invention is a kit for preparing a usable fungicidal corn- position, the kit comprising a) a composition comprising mefentrifluconazole and at least one auxiliary; and b) a composition comprising at least one component II) and at least one auxiliary; and optionally c) a composition comprising at least one auxiliary and optionally a further active component as defined herein.

When preparing the compositions, it is preferred to employ the pure active compounds, to which further active compounds against pests, such as insecticides, herbicides, fungicides or else herbicidal or growth-regulating active compounds or fertilizers can be added as further active components according to need.

In the context of the present invention, the term plant refers to an entire plant, a part of the plant or the propagation material of the plant.

The separate or joint application of the compounds of the inventive compositions is carried out by spraying or dusting the seeds, the seedlings, the plants or the soils before or after sowing of the plants or before or after emergence of the plants.

Customary application rates in the protection of materials are, for example, from 0.01 g to 1000 g of active compounds per m ² treated material, desirably from 0.1 g to 50 g per m ² . For use in spray compositions, the content of the mixture of the active ingredients is from 0.001 to 80 weight %, preferably from 0.01 to 50 weight % and most preferably from 0.01 to 15 weight %.

Experimental Part:

The fungicidal action of the mixtures according to the invention can be shown by the tests de- scribed below.

The visually determined percentages of infected leaf areas are converted into efficacies in % of the untreated control.

The efficacy (E) is calculated as follows using Abbot's formula:

E = (1 - a/b) 100

a corresponds to the fungicidal infection of the treated plants in % and

b corresponds to the fungicidal infection of the untreated (control) plants in %

An efficacy of 0 means that the infection level of the treated plants corresponds to that of the untreated control plants; an efficacy of 100 means that the treated plants were not infected.

The expected efficacies of active compound combinations may be determined using Colby's formula (Colby, S.R. "Calculating synergistic and antagonistic responses of herbicide combina- tions", Weeds, 1J5, pp. 20-22, 1967) and compared with the observed efficacies.

Colby's formula:

E = x + y - x -y/100

E expected efficacy, expressed in % of the untreated control, when using the mixture of the active compounds A and B at the concentrations a and b

x efficacy, expressed in % of the untreated control, when using the active compound A at the concentration a

y efficacy, expressed in % of the untreated control, when using the active compound B at the concentration b.

Microtest:

The active compounds were formulated separately as a stock solution having a concentration of 10000 ppm in dimethyl sulfoxide.

1. Activity against leaf blotch on wheat caused by Septoria /·/¾£/ (Septtr)

The stock solutions were mixed according to the ratio, pipetted onto a micro titer plate (MTP) and diluted with water to the stated concentrations. A spore suspension of Septoria tritici in an aqueous biomalt or yeast-bactopeptone-glycerine solution was then added. The plates were placed in a water vapor-saturated chamber at a temperature of 18°C. Using an absorption pho- tometer, the MTPs were measured at 405 nm 7 days after the inoculation.

2. Activity against Colletotrichum truncatum (Colldu), CoHetotrichum orbicularum (Col I la) or Sderotinia sderotiorum (Sclesc) in the microtiterplate test The stock solutions were mixed according to the ratio, pipetted onto a micro titer plate (MTP) and diluted with water to the stated concentrations. Spores of the respective pathogen in an aqueous biomalt or yeast-bactopeptone-glycerine solution were then added. The plates were placed in a water vapor-saturated chamber at a temperature of 18°C. Using an absorption pho- tometer, the MTPs were measured at 405 nm 7 days after the inoculation.

The measured parameters were compared to the growth of the active compound-free control variant (100%) and the fungus-free and active compound-free blank value to determine the rela- tive growth in % of the pathogens in the respective active compounds.

Table E1 : Activity against leaf blotch on wheat caused by Septoria tritici (Septtr)

Table E2. Activity against CoHetotrichum truncatum in the microtiterplate test (Colldu)

Table E3. Activity against CoHetotrichum orbicu!arum in the microtiterplate test (Collla)

Table E4. Activity against Sderotinia sderotiorum in the microtiterplate test (Sclesc)