Title:
FUSED BICYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2024/099386
Kind Code:
A1
Abstract:
The present application relates to the field of pharmaceutical chemistry, relates to a fused bicyclic compound, and in particular relates to a compound represented by formula (II), a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition containing the compound, and a use thereof in treating diseases.
Inventors:
LIU XIN (CN)
QIN HUI (CN)
LI KE (CN)
CHEN PUZHOU (CN)
ZHANG YINSHENG (CN)
QIN HUI (CN)
LI KE (CN)
CHEN PUZHOU (CN)
ZHANG YINSHENG (CN)
Application Number:
PCT/CN2023/130659
Publication Date:
May 16, 2024
Filing Date:
November 09, 2023
Export Citation:
Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
International Classes:
C07D487/04; A61K31/429; A61K31/498; A61K31/4985; A61P35/00; C07D513/04
Domestic Patent References:
| WO2022225934A1 | 2022-10-27 | |||
| WO2022218296A1 | 2022-10-20 | |||
| WO2023056039A1 | 2023-04-06 | |||
| WO2023051716A1 | 2023-04-06 | |||
| WO2023051807A1 | 2023-04-06 |
Foreign References:
| CN114144413A | 2022-03-04 | |||
| CN102341394A | 2012-02-01 |
Other References:
REN JUNKANG, QUAN XU, LIU YING, LI JIANI, ZHANG XIAOYU, LI ZHIYU, ZHANG XIAOMENG: "Synthesis and in vitro biological evaluation of 3-ethyl-1,5-naphthyridin-2(1H)-one derivatives as potent PARP-1 selective inhibitors and PARP-1 DNA trappers", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ELSEVIER, AMSTERDAM NL, vol. 78, 31 October 2022 (2022-10-31), Amsterdam NL , pages 129046, XP093067861, ISSN: 0960-894X, DOI: 10.1016/j.bmcl.2022.129046
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