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Title:
FUSED BICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2019/034096
Kind Code:
A1
Abstract:
Fused bicyclic compounds and uses thereof in medicine. In particular, provided are fused bicyclic compounds used as ASK1 active regulator and and use of the compounds in the manufacture of a drug for treating a disease regulated by ASK1. Further provided are a pharmaceutical composition and a method of treating a disease regulated by ASK1 comprising administering the compounds or pharmaceutical composition thereof.

Inventors:
YANG XINYE (CN)
PAN SHENGQIANG (CN)
MA FACHENG (CN)
ZHANG YINGXUN (CN)
WANG XIAOJUN (CN)
ZHANG YINGJUN (CN)
JIN CHUANFEI (CN)
ZHANG JI (CN)
Application Number:
PCT/CN2018/100736
Publication Date:
February 21, 2019
Filing Date:
August 16, 2018
Export Citation:
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Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D471/04; A61K31/4353; A61K31/5365; A61K31/542; A61P9/00; A61P25/28; A61P29/00; A61P37/00; C07D498/04; C07D513/04
Domestic Patent References:
WO2018133866A12018-07-26
WO2018133865A12018-07-26
WO2018157856A12018-09-07
WO2018151830A12018-08-23
WO2018157857A12018-09-07
WO2011008709A12011-01-20
WO2012003387A12012-01-05
WO2016049069A12016-03-31
Foreign References:
CN107793400A2018-03-13
Other References:
DATABASE REGISTRY 23 September 2014 (2014-09-23), Database accession no. RN 1624777-36-1
DATABASE REGISTRY 8 July 2015 (2015-07-08), Database accession no. RN 1797200-32-8
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