FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS

Title:

FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS

Document Type and Number:

WIPO Patent Application WO/2023/136589

Kind Code:

A1

Abstract:

The invention provides novel substituted heterocyclic compounds represented by the Formulas (I), or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as agonists of Stimulator of Interferon Genes (STING) and are useful in the treatment of cancers and certain infectious diseases.

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Inventors:

SEO JEONGBEOB (KR)
HAN CHEOLKYU (KR)
YOON CHEOLHWAN (KR)
YANG INHO (KR)
KIM SUNJOO (KR)
KANG HONGJUN (KR)
SHIN YOUNGDO (KR)
JEON SEEUN (KR)
LEE JUNGWOO (KR)
KANG BYUNGNAM (KR)
JEON SUNHWA (KR)
LEE JINWOO (KR)

Application Number:

PCT/KR2023/000464

Publication Date:

July 20, 2023

Filing Date:

January 10, 2023

Export Citation:

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Assignee:

BISICHEM CO LTD (KR)

International Classes:

C07D403/14; A61K31/4184; A61K31/454; A61K31/496; A61K31/5377; A61P35/00

Domestic Patent References:

WO2017175147A1	2017-10-12
WO2020156363A1	2020-08-06
WO2021202984A1	2021-10-07

Foreign References:

CN113248475A	2021-08-13
CN112521371A	2021-03-19

Attorney, Agent or Firm:

LEE, Jongseung (KR)

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