FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF

Title:

FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/007979

Kind Code:

A1

Abstract:

Disclosed are fused imidazole derivatives, preparation methods therefor and medical uses thereof. Specifically, the present disclosure relates to a fused imidazole derivative as shown in general formula (IM), a preparation method therefor, a pharmaceutical composition containing the derivative, and the use of same as a therapeutic agent, in particular the use thereof as a GLP-1 receptor agonist, and the use thereof in the preparation of drugs for the treatment and/or prevention of diabetes.

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Inventors:

YANG FANGLONG (CN)
ZHANG LING (CN)
ZHENG LIANGLIANG (CN)
HE FENG (CN)
TAO WEIKANG (CN)

Application Number:

PCT/CN2021/115915

Publication Date:

January 13, 2022

Filing Date:

September 01, 2021

Export Citation:

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Assignee:

JIANGSU HENGRUI MEDICINE CO (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)

International Classes:

C07D413/14; A61K31/496; A61P3/10; C07D405/04

Domestic Patent References:

WO2019239319A1	2019-12-19
WO2020103815A1	2020-05-28
WO2010114824A1	2010-10-07
WO2009111700A2	2009-09-11
WO2010114824A1	2010-10-07
WO2018109607A1	2018-06-21
WO2019239319A1	2019-12-19
WO2018056453A1	2018-03-29
WO2003099805A1	2003-12-04

Other References:

T.W.GREENEP.G.M.WUTS: "Protective Groups in Organic Synthesis"
See also references of EP 4209490A4

Attorney, Agent or Firm:

GE CHENG & CO., LTD (CN)

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