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Title:
FUSION PROTEIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/061350
Kind Code:
A1
Abstract:
Provided is a fusion protein consisting of SIRPαV2 and a CD3 antibody.

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Inventors:
SUN ZHE (CN)
YANG YING (CN)
Application Number:
PCT/CN2023/120732
Publication Date:
March 28, 2024
Filing Date:
September 22, 2023
Export Citation:
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Assignee:
GUANGZHOU LINTONPHARM CO LTD (CN)
International Classes:
C07K16/46; A61K39/395; A61P35/00; C07K16/28; C07K16/30; C07K16/32; C12N15/12; C12N15/13; C12N15/63
Domestic Patent References:
WO2023072217A12023-05-04
WO2022199555A12022-09-29
WO2021190441A12021-09-30
Foreign References:
CN104098698A2014-10-15
CN104704004A2015-06-10
CN111423515A2020-07-17
Other References:
XU LIJUN; WANG SHANLONG; LI JIE; LI BINGYU: "CD47/SIRPα blocking enhances CD19/CD3-bispecific T cell engager antibody-mediated lysis of B cell malignancies", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ELSEVIER, AMSTERDAM NL, vol. 509, no. 3, 1 January 1900 (1900-01-01), Amsterdam NL , pages 739 - 745, XP085579685, ISSN: 0006-291X, DOI: 10.1016/j.bbrc.2018.12.175
Attorney, Agent or Firm:
BEIJING CEMO LEADER INTELLECTUAL PROPERTY AGENCY et al. (CN)
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