Title:
FUSION PROTEINS COMPRISING 072 CORE PEPTIDE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/078436
Kind Code:
A1
Abstract:
Provided are compositions of proteins based on fusion of one or more copy of the core peptide to the Fc fragment of human immunoglobulin and their use in treating diseases propagated by inflammations associated with tissue injuries.
Inventors:
ZHOU QUNMIN (CN)
FANG XIANFENG (CN)
LI DONGLING (CN)
MU LIBING (CN)
FANG XIANFENG (CN)
LI DONGLING (CN)
MU LIBING (CN)
Application Number:
PCT/CN2022/130186
Publication Date:
May 11, 2023
Filing Date:
November 07, 2022
Export Citation:
Assignee:
ACROIMMUNE GUANGZHOU BIOTECH LTD (CN)
International Classes:
A61K35/32; A61L27/52; A61L27/54; C12N5/077
Domestic Patent References:
| WO2006088494A2 | 2006-08-24 | |||
| WO2007024249A2 | 2007-03-01 |
Foreign References:
| CN110028588A | 2019-07-19 |
Other References:
BÄCKSTRÖM M. ET AL.: "Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells", THE BIOCHEMICAL JOURNAL, vol. 376, no. Pt 3, 15 December 2003 (2003-12-15), pages 677 - 686, XP002452717, DOI: 10.1042/BJ20031130
LIU Y. ET AL.: "Sialoside-based pattern recognitions discriminating infections from tissue injuries", CURRENT OPINION IN IMMUNOLOGY, vol. 23, no. 1, 3 January 2011 (2011-01-03), pages 41 - 45, XP028371147, DOI: 10.1016/j.coi.2010.10.004
KUBITZKI T. ET AL.: "Immobilisation of bovine enterokinase and application of the immobilised enzyme in fusion protein cleavage", BIOPROCESS AND BIOSYSTEMS ENGINEERING, vol. 31, no. 3, 9 January 2008 (2008-01-09), pages 173 - 182, XP019590880
LIU Y. ET AL.: "Sialoside-based pattern recognitions discriminating infections from tissue injuries", CURRENT OPINION IN IMMUNOLOGY, vol. 23, no. 1, 3 January 2011 (2011-01-03), pages 41 - 45, XP028371147, DOI: 10.1016/j.coi.2010.10.004
KUBITZKI T. ET AL.: "Immobilisation of bovine enterokinase and application of the immobilised enzyme in fusion protein cleavage", BIOPROCESS AND BIOSYSTEMS ENGINEERING, vol. 31, no. 3, 9 January 2008 (2008-01-09), pages 173 - 182, XP019590880
Attorney, Agent or Firm:
SHANGHAI DIANSHI PARTNERS, P.C. (CN)
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