Title:
GAMMA-AMINOBUTYRIC ACID DERIVATIVE COMPRISING POLYCYCLIC STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/093678
Kind Code:
A1
Abstract:
The invention relates to the field of pharmaceuticals. Specifically, the present application relates to a voltage-gated calcium ion channel α2δ subunit ligand comprising a polycyclic γ-aminobutyric acid structure represented by general formula I, a method for preparing same, and use thereof in the treatment of chronic neuropathic pain, epilepsy, and anxiety.
Inventors:
ZHAO GUILONG (CN)
GAO ZHAOBING (CN)
WU QINGQING (CN)
ZHENG YUEMING (CN)
SUN LI (CN)
TIAN FUYUN (CN)
HE JINYAN (CN)
XU HAIYAN (CN)
CHEN YUTING (CN)
ZHAN LI (CN)
JIN ZHENGSHENG (CN)
GU YUELING (CN)
CHENG XINQIANG (CN)
ZHANG WENBO (CN)
ZHANG YUANWEN (CN)
GAO ZHAOBING (CN)
WU QINGQING (CN)
ZHENG YUEMING (CN)
SUN LI (CN)
TIAN FUYUN (CN)
HE JINYAN (CN)
XU HAIYAN (CN)
CHEN YUTING (CN)
ZHAN LI (CN)
JIN ZHENGSHENG (CN)
GU YUELING (CN)
CHENG XINQIANG (CN)
ZHANG WENBO (CN)
ZHANG YUANWEN (CN)
Application Number:
PCT/CN2023/125229
Publication Date:
May 10, 2024
Filing Date:
October 18, 2023
Export Citation:
Assignee:
ZHONGSHAN INST FOR DRUG DISCOVERY SIMM CAS (CN)
SHANGHAI INST MATERIA MEDICA CAS (CN)
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
C07C229/32; A61K31/195; A61P25/04; A61P25/08; A61P25/22; C07C227/04
Domestic Patent References:
| WO2010084798A1 | 2010-07-29 |
Foreign References:
| CN106928080A | 2017-07-07 | |||
| CN101878193A | 2010-11-03 | |||
| CN107848952A | 2018-03-27 | |||
| CN1279673A | 2001-01-10 |
Attorney, Agent or Firm:
JIAQUAN IP LAW (CN)
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