Title:
GENETIC MARKERS FOR OBESITY
Document Type and Number:
WIPO Patent Application WO2005038370
Kind Code:
A3
Abstract:
The present invention is directed to new genetic variants or polymorphisms at the perilipin locus (PLIN) including PLIN1: 6209T (allele 1) >C (allele 2); PLIN3 10171 (allele 1) A >T (allele 2); PLIN4: 11482G (allele 1) >A (allele 2); PLIN5: 13041A (allele 1) >G (allele 2) and PLIN6: 14995A (allele 1) >T (allele 2), and their use in diagnostic and prognostic applications for obesity and and obesity-related diseases, such as metabolic syndrome and cardiovascular disease.
More Like This:
| JP2005532072 | Equipment and methods for isolating nucleic acids from samples |
| WO2000068242 | COLLAGEN-BINDING PROTEINS FROM ENTEROCOCCAL BACTERIA |
| WO/2002/061141 | DETECTION OF BORDETELLA |
Inventors:
ORDOVAS JOSE M (US)
QI LU (US)
GREENBERG ANDREW (US)
CORELLA DOLORES (US)
QI LU (US)
GREENBERG ANDREW (US)
CORELLA DOLORES (US)
Application Number:
PCT/US2004/018743
Publication Date:
December 29, 2005
Filing Date:
June 10, 2004
Export Citation:
Assignee:
UNIV TUFTS (US)
ORDOVAS JOSE M (US)
QI LU (US)
GREENBERG ANDREW (US)
CORELLA DOLORES (US)
ORDOVAS JOSE M (US)
QI LU (US)
GREENBERG ANDREW (US)
CORELLA DOLORES (US)
International Classes:
C07H21/04; C12P19/34; C12Q1/68; F26B; (IPC1-7): C07H21/04; C12P19/34; C12Q1/68
Other References:
LUCENTINI J ET AL: "Gene Association Studies Typically Wrong.", THE SCIENTIST., vol. 18, no. 24, 20 December 2004 (2004-12-20), pages 1 - 4, XP002985230
KROESE M ET AL: "Genetic Tests and Their Evaluation: Can We Answer the Key Questions?.", GENETICS IN MEDICINE., vol. 6, November 2004 (2004-11-01) - December 2004 (2004-12-01), pages 475 - 482, XP008061434
MOTTAGUI-TABAR S ET AL: "Evidence for an Important Role of Perilipin in the Regulation of Human Adipocyte Lipolysis.", DIABETOLOGIA., vol. 46, 2003, pages 789 - 797, XP002992997
See also references of EP 1673383A4
KROESE M ET AL: "Genetic Tests and Their Evaluation: Can We Answer the Key Questions?.", GENETICS IN MEDICINE., vol. 6, November 2004 (2004-11-01) - December 2004 (2004-12-01), pages 475 - 482, XP008061434
MOTTAGUI-TABAR S ET AL: "Evidence for an Important Role of Perilipin in the Regulation of Human Adipocyte Lipolysis.", DIABETOLOGIA., vol. 46, 2003, pages 789 - 797, XP002992997
See also references of EP 1673383A4
Download PDF:
Previous Patent: DEVICE AND METHOD FOR DRYING A TREATED PRODUCT
Next Patent: METHOD FOR DRYING A PARTICULARLY LIQUID OR PASTY MATERIAL FOR DRYING
Next Patent: METHOD FOR DRYING A PARTICULARLY LIQUID OR PASTY MATERIAL FOR DRYING