Title:
GENETICALLY HUMANIZED MAMMALS EXPRESSING HUMAN SERUM ALBUMIN AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/085967
Kind Code:
A1
Abstract:
Genetically humanized mammals expressing human albumin and uses thereof. In some embodiments, the genome of the non-human transgenic mammal includes a polynucleotide sequence encoding human albumin, which may include a modification of human albumin gene.
Inventors:
LAI LIANGXUE (CN)
Application Number:
PCT/CN2016/104956
Publication Date:
May 17, 2018
Filing Date:
November 08, 2016
Export Citation:
Assignee:
GUANGZHOU INST BIOMED & HEALTH (CN)
International Classes:
C12N15/14; C07K14/765
Domestic Patent References:
| WO2000061725A1 | 2000-10-19 | |||
| WO2002083897A1 | 2002-10-24 |
Foreign References:
| EP1557084A2 | 2005-07-27 | |||
| CN105985981A | 2016-10-05 | |||
| US5633076A | 1997-05-27 |
Other References:
GOU, DEMING ET AL.: "Production of Transgenic Mice from Eggs Microinjected with HSA Fusion Gene", CHINESE JOURNAL OF VETERINARY SCIENCE, vol. 16, 30 November 1996 (1996-11-30), pages 570 - 575
LIANG, ZHENXIN ET AL.: "Progress and Technology in Mammary Gland Bioreactor of Transgenic Animals", CHINA BIOTECHNOLOGY, vol. 35, no. 2, 31 December 2015 (2015-12-31), pages 92 - 98, XP055484391
LIANG, ZHENXIN ET AL.: "Progress and Technology in Mammary Gland Bioreactor of Transgenic Animals", CHINA BIOTECHNOLOGY, vol. 35, no. 2, 31 December 2015 (2015-12-31), pages 92 - 98, XP055484391
Attorney, Agent or Firm:
BEIJING KEYI INTELLECTUAL PROPERTY FIRM (CN)
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