Title:
GENOME EDITING METHOD BASED ON CRISPR/CAS9 SYSTEM AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/201653
Kind Code:
A1
Abstract:
The present invention pertains to a genome editing method based on a CRISPR/CAS9 system, and a use thereof. A CRISPR system using oligonucleotide-induced mutagenesis and mismatch guide RNA (sgRNA) according to the present invention achieves a significant genome editing effect on target DNA. Thus, it is expected that the CRISPR system of the present invention will be able to be used in a wide range of fields, such as compositions for gene editing using genetic scissors, genome level screening, therapeutic agents for treating various diseases including cancer, the development of compositions for disease diagnosis or imaging, and the development of transgenic plants and animals.
Inventors:
LEE SANG JUN (KR)
LEE HO JOUNG (KR)
KIM HYUN JU (KR)
LEE HO JOUNG (KR)
KIM HYUN JU (KR)
Application Number:
PCT/KR2021/004155
Publication Date:
October 07, 2021
Filing Date:
April 02, 2021
Export Citation:
Assignee:
CHUNGANG UNIV INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR)
International Classes:
C12N15/63; C12N9/22; C12N15/10; C12N15/113
Domestic Patent References:
| WO2016094872A1 | 2016-06-16 | |||
| WO2017106251A1 | 2017-06-22 | |||
| WO2016094867A1 | 2016-06-16 | |||
| WO2017184786A1 | 2017-10-26 | |||
| WO2017160752A1 | 2017-09-21 |
Foreign References:
| KR20190071621A | 2019-06-24 |
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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