GLUCOSE ISOMERASE MUTANT AND ITS USE - BIORIGHT WORLDWIDE CO LTD

Title:

GLUCOSE ISOMERASE MUTANT AND ITS USE

Document Type and Number:

WIPO Patent Application WO/2006/024204

Kind Code:

A1

Abstract:

A series of gene engineered Thermoanaerobacterium saccharolyticum glucose isomerases having heat resistance, high catalytic activity, which are useful in levulose content determinating. The said glucose isomerases have a mutation at (186) position and having at least three mutation at (139, 182, 187) and (229) position of parent sequence (2), which convert the substrate-levulose into glucose, thus can be used to determine the levulose content of human body, or of certain organ within body, or of other organism, or of goods.

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Inventors:

WANG JUN (CN)
FU RONGZHAO (CN)
JIN CAIKE (CN)
SHEN DONG (CN)

Application Number:

PCT/CN2004/001357

Publication Date:

March 09, 2006

Filing Date:

November 26, 2004

Export Citation:

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Assignee:

BIORIGHT WORLDWIDE CO LTD
WANG JUN (CN)
FU RONGZHAO (CN)
JIN CAIKE (CN)
SHEN DONG (CN)

International Classes:

C12N15/61; C12N9/92; (IPC1-7): C12N9/92; C12N15/61

Foreign References:

CN1213003A	1999-04-07
CN1418949A	2003-05-21
CN1156182A	1997-08-06

Other References:

DATABASE GENBANK [online] 28 October 1993 (1993-10-28), LEE Y.E., XP003002163, accession no. NCBI Database accession no. (L09699)

Attorney, Agent or Firm:

TEE & HOWE INTELLECTUAL PROPERTY ATTORNEYS (Beijing Capital Times Square 88, Xichang' an Avenu, Xicheng District Beijing 1, CN)

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