Title:
GLYCYRRHETINIC ACID DERIVATIVE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2015/076325
Kind Code:
A1
Abstract:
[Problem] To provide a novel glycyrrhetinic acid derivative. [Solution] A glycyrrhetinic acid derivative represented by formula (1).
(1)
Inventors:
TAKEUCHI HIDEYUKI (JP)
SUZUMURA AKIO (JP)
SUZUMURA AKIO (JP)
Application Number:
PCT/JP2014/080732
Publication Date:
May 28, 2015
Filing Date:
November 20, 2014
Export Citation:
Assignee:
UNIV NAGOYA NAT UNIV CORP (JP)
TAKEUCHI HIDEYUKI (JP)
SUZUMURA AKIO (JP)
TAKEUCHI HIDEYUKI (JP)
SUZUMURA AKIO (JP)
International Classes:
A61K31/58; C07J63/00; A61P25/00; A61P43/00
Domestic Patent References:
| WO2010007788A1 | 2010-01-21 | |||
| WO2010103046A1 | 2010-09-16 | |||
| WO2007088712A1 | 2007-08-09 |
Foreign References:
| JP2009511511A | 2009-03-19 | |||
| US20140121166A1 | 2014-05-01 | |||
| JP4649549B2 | 2011-03-09 |
Other References:
DENISE V. KRATSCHMAR ET AL.: "Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting llbeta- hydroxysteroid dehydrogenase type 2", JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, vol. 125, 2011, pages 129 - 142, XP028385076
PROG. MED., vol. 5, 1985, pages 2157 - 2161
"Bunshi Sekkei", vol. 7, 1990, HIROKAWA SHOTEN, article "Iyakuhin no Kaihatsu", pages: 163 - 198
DOI ET AL., AM J PATHOL., vol. 175, no. 5, 2009, pages 2121 - 32
MOURI ET AL., FASEB J., vol. 21, 2007, pages 2135 - 2148
NAGAI ET AL., FASEB J., vol. 17, 2003, pages 50 - 52
PROG. MED., vol. 5, 1985, pages 2157 - 2161
"Bunshi Sekkei", vol. 7, 1990, HIROKAWA SHOTEN, article "Iyakuhin no Kaihatsu", pages: 163 - 198
DOI ET AL., AM J PATHOL., vol. 175, no. 5, 2009, pages 2121 - 32
MOURI ET AL., FASEB J., vol. 21, 2007, pages 2135 - 2148
NAGAI ET AL., FASEB J., vol. 17, 2003, pages 50 - 52
Attorney, Agent or Firm:
YAGUCHI, Taro (JP)
Taro Yaguchi (JP)
Taro Yaguchi (JP)
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