Title:
GLYPICAN-3 ANTIBODY AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/001155
Kind Code:
A1
Abstract:
The present application discloses a glypican-3 antibody and an application thereof. A heavy chain complementarity-determining region of the glypican-3 antibody comprises an amino acid sequence shown in SEQ ID No. 6-8, and a light chain complementarity-determining region of the glypican-3 antibody comprises an amino acid sequence shown in SEQ ID No. 14-16. The glypican-3 antibody can specifically bind to glypican-3 with high affinity, can activate T lymphocytes, and has application prospects in improving immune cell activity, enhancing immune response, preventing and treating tumor and infectious diseases, and the like.
Inventors:
ZHANG WENJUN (CN)
LIU MIN (CN)
TIAN WENWU (CN)
LI FENG (CN)
QIN LUYING (CN)
LIU MIN (CN)
TIAN WENWU (CN)
LI FENG (CN)
QIN LUYING (CN)
Application Number:
PCT/CN2022/106547
Publication Date:
January 26, 2023
Filing Date:
July 19, 2022
Export Citation:
Assignee:
EXCELMAB INC (CN)
International Classes:
C07K16/30; A61K39/395; C07K16/46; C12N15/13
Foreign References:
| CN113354737A | 2021-09-07 | |||
| CN112079932A | 2020-12-15 | |||
| CN106397593A | 2017-02-15 | |||
| JP5941235B1 | 2016-06-29 | |||
| CN105037540A | 2015-11-11 | |||
| CN111732659A | 2020-10-02 |
Attorney, Agent or Firm:
CHOFN INTELLECTUAL PROPERTY (CN)
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