Title:
GRANULES FOR SUSPENSION
Document Type and Number:
WIPO Patent Application WO/2024/058099
Kind Code:
A1
Abstract:
The present disclosure provides granules for suspension. Specifically, the present disclosure is a pharmaceutical composition comprising: a compound represented by formula 1 or a pharmaceutically acceptable salt or solvate thereof; a binder; and a dispersant. The binder includes a binder selected from the group consisting of a cellulose-based binder, a povidone-based binder, a vinyl alcohol-based binder, and a polysaccharide thickener-based binder. The dispersant is selected from the group consisting of an inorganic salt dispersant, an ether dispersant, a starch dispersant, a cellulose-based dispersant, and a fatty acid ester salt dispersant.
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Inventors:
HOKONOHARA KAZUHIRO (JP)
MARUYAMA MEGUMI (JP)
HAN JIN (JP)
ONOUE YOSHIHIRO (JP)
NOBUTO TOMOHIRO (JP)
MARUYAMA MEGUMI (JP)
HAN JIN (JP)
ONOUE YOSHIHIRO (JP)
NOBUTO TOMOHIRO (JP)
Application Number:
PCT/JP2023/032990
Publication Date:
March 21, 2024
Filing Date:
September 11, 2023
Export Citation:
Assignee:
SUMITOMO PHARMA CO LTD (JP)
PTC THERAPEUTICS INC (US)
PTC THERAPEUTICS INC (US)
International Classes:
A61K31/16; A61K9/107; A61K9/14; A61K47/04; A61K47/10; A61K47/14; A61K47/32; A61K47/34; A61K47/36; A61K47/38
Domestic Patent References:
| WO2010087447A1 | 2010-08-05 |
Foreign References:
| JP2018500326A | 2018-01-11 | |||
| JP2007332097A | 2007-12-27 | |||
| JP2006306766A | 2006-11-09 |
Other References:
NODA NAOTO, HAMATANI TATSUTO, SHIBUE YUTA, TAKAGAKI TAKESHI, KITAMURA ATSUSHI, HARANAKA MIWA, OGAMA YOICHIRO, KAKUYAMA HIROYOSHI: "Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of EPI‐589 in Healthy Participants", CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, WILEY-BLACKWELL PUBLISHING LTD., GB, vol. 11, no. 10, 1 October 2022 (2022-10-01), GB , pages 1136 - 1146, XP093146007, ISSN: 2160-763X, DOI: 10.1002/cpdd.1146
Attorney, Agent or Firm:
KAMADA, Mitsunori et al. (JP)
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