GRK2 INHIBITORS AND USES THEREOF - CYGNAL THERAPEUTICS INC

Title:

GRK2 INHIBITORS AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/242844

Kind Code:

A8

Abstract:

The present disclosure features useful methods to treat cancer, e.g., in a subject in need thereof. The methods described herein are useful in the treatment of disorders associated with GRK2 expression, e.g., cancer or cardiovascular disease. The present disclosure also features compounds (e.g., GRK2 inhibitors), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof.

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Inventors:

PIIZZI GRAZIA (US)
CHEKLER EUGENE LVOVICH PIATNITSKI (US)
HUROV JONATHAN BARRY (US)
LANTERMANN ALEXANDRA (US)
COUTO KILEY MARIE (US)
XU HUA (US)
SARKER SOURAV (US)

Application Number:

PCT/US2021/034225

Publication Date:

January 06, 2022

Filing Date:

May 26, 2021

Export Citation:

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Assignee:

CYGNAL THERAPEUTICS INC (US)

International Classes:

C07D401/14

Attorney, Agent or Firm:

HAMZIK, Philip J. et al. (US)

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