Title:
HETEROCYCLIC DERIVATIVES AS Nav1.7 and Nav1.8 BLOCKERS
Document Type and Number:
WIPO Patent Application WO/2020/138271
Kind Code:
A1
Abstract:
The present invention relates to heterocyclic derivatives which have blocking activities of voltage gated sodium channels as the Nav1.7 and Nav1.8 channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
Inventors:
YAMAGISHI TATSUYA (JP)
KAWAMURA KIYOSHI (JP)
SHISHIDO YUJI (JP)
YAMAGUCHI RYUICHI (JP)
MORITA MIKIO (JP)
GAJA NORIKAZU (JP)
KAWAMURA KIYOSHI (JP)
SHISHIDO YUJI (JP)
YAMAGUCHI RYUICHI (JP)
MORITA MIKIO (JP)
GAJA NORIKAZU (JP)
Application Number:
PCT/JP2019/051086
Publication Date:
July 02, 2020
Filing Date:
December 26, 2019
Export Citation:
Assignee:
RAQUALIA PHARMA INC (JP)
International Classes:
A61K31/4427; A61K31/4439; A61K31/4545; A61K31/4709; A61K31/506; A61P25/00; C07D401/12; C07D401/14; C07D403/12
Domestic Patent References:
| WO2018235851A1 | 2018-12-27 | |||
| WO2013161308A1 | 2013-10-31 | |||
| WO2017106872A1 | 2017-06-22 | |||
| WO2013088315A1 | 2013-06-20 | |||
| WO2013118854A1 | 2013-08-15 | |||
| WO2013161312A1 | 2013-10-31 |
Other References:
FILE REGISTRY ON STN, RN 2060734-63-4, Entered STN: 29 Jan 2017 The whole document
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
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