Title:
HALIDE-FREE AMMONIUM SILANES
Document Type and Number:
WIPO Patent Application WO/2023/215521
Kind Code:
A3
Abstract:
Provided herein are antimicrobial quaternary ammonium organosilanes, compositions and formulations thereof, including powdered and solid formulations, and methods of use to treat microbial infections, including polymicrobial infections, on or in a host such as an animal or human. The quaternary ammonium organosilanes and compositions thereof described herein can also be used as cleaners, sanitizers, preservatives, disinfectants, or as pesticides to treat destructive biofilm infections.
Inventors:
ALLRED GARY (US)
LIEBESKIND LANNY (US)
CAST WILLIAM (US)
HILLIARD CARL (US)
LIEBESKIND LANNY (US)
CAST WILLIAM (US)
HILLIARD CARL (US)
Application Number:
PCT/US2023/021069
Publication Date:
March 14, 2024
Filing Date:
May 04, 2023
Export Citation:
Assignee:
TOPIKOS SCIENT INC (US)
International Classes:
A61K31/695; A61K45/06; A61P31/00; C07C309/28; C07F7/08
Domestic Patent References:
| WO2021077119A1 | 2021-04-22 |
Foreign References:
| US20080009643A1 | 2008-01-10 | |||
| US20120196953A1 | 2012-08-02 | |||
| US20210253607A1 | 2021-08-19 |
Other References:
DATABASE Pubchem compound 5 December 2017 (2017-12-05), ANONYMOUS : "N,N-Dimethyl-N-(3-(trihydroxysilyl)propyl)octadecan-1aminium", XP093149671, retrieved from Pubchem Database accession no. 21365909
DATABASE Pubchem compound 24 June 2005 (2005-06-24), ANONYMOUS : "N-Tris(hydroxymethyl)methyl-2- aminoethanesulfonic acid", XP093150099, retrieved from Pubchem Database accession no. 81831
DATABASE Pubchem compound 6 March 2005 (2005-03-06), ANONYMOUS : "Tromethamine", XP093150105, retrieved from Pubchem Database accession no. 6503
DATABASE Pubchem compound 26 March 2005 (2005-03-26), ANONYMOUS : "4-Hydroxy-3,3bis(hydroxymethyl)butane-1-sulfonic acid", XP093150110, retrieved from Pubchem Database accession no. 296494
DATABASE Pubchem compound 19 August 2012 (2012-08-19), ANONYMOUS PUBCHEM : "2- [Bis(hydroxymethyl)amino]ethanesul fonic acid", XP093150116, retrieved from Pubchem Database accession no. 57925512
DATABASE Pubchem compound 10 November 2021 (2021-11-10), ANONYMOUS : "Dimethyl-octadecyl-[3-[tris(oxiran-2-ylmethoxy)silyl]propyl]azanium", XP093150119, retrieved from Pubchem Database accession no. 156729836
DATABASE Pubchem compound 24 June 2005 (2005-06-24), ANONYMOUS : "N-Tris(hydroxymethyl)methyl-2- aminoethanesulfonic acid", XP093150099, retrieved from Pubchem Database accession no. 81831
DATABASE Pubchem compound 6 March 2005 (2005-03-06), ANONYMOUS : "Tromethamine", XP093150105, retrieved from Pubchem Database accession no. 6503
DATABASE Pubchem compound 26 March 2005 (2005-03-26), ANONYMOUS : "4-Hydroxy-3,3bis(hydroxymethyl)butane-1-sulfonic acid", XP093150110, retrieved from Pubchem Database accession no. 296494
DATABASE Pubchem compound 19 August 2012 (2012-08-19), ANONYMOUS PUBCHEM : "2- [Bis(hydroxymethyl)amino]ethanesul fonic acid", XP093150116, retrieved from Pubchem Database accession no. 57925512
DATABASE Pubchem compound 10 November 2021 (2021-11-10), ANONYMOUS : "Dimethyl-octadecyl-[3-[tris(oxiran-2-ylmethoxy)silyl]propyl]azanium", XP093150119, retrieved from Pubchem Database accession no. 156729836
Attorney, Agent or Firm:
BELLOWS, Brent, R. et al. (US)
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