HALO- OR HYDROXY-SUBSTITUTED NOCATHIACIN ANTIBIOTICS

Title:

HALO- OR HYDROXY-SUBSTITUTED NOCATHIACIN ANTIBIOTICS

Document Type and Number:

WIPO Patent Application WO2000068413

Kind Code:

A8

Abstract:

Fermentattion of Nocardia sp- ATCC-202099 in the presence of a halogen- or hydroxy-substituted tryptophan precursor yields a novel corresponding halogen- or hydroxy-substituted nocathiacin compound which has broad spectrum antibiotic activity against Gram-positive bacteria and has in vivo efficacy in animals.

Inventors:

LI WENYING
LEET JOHN E
LAM KIN S

Application Number:

PCT/US2000/011859

Publication Date:

June 14, 2001

Filing Date:

May 02, 2000

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Assignee:

BRISTOL MYERS SQUIBB CO (US)

International Classes:

C12P1/06; A61K31/7052; A61P31/04; C07H17/00; C12P17/08; C12P17/18; C12P19/60; C12P21/04; C12R1/365; (IPC1-7): C12P21/04; C12P17/14; C12P17/18

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