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Title:
HALO- OR HYDROXY-SUBSTITUTED NOCATHIACIN ANTIBIOTICS
Document Type and Number:
WIPO Patent Application WO2000068413
Kind Code:
A8
Abstract:
Fermentattion of Nocardia sp- ATCC-202099 in the presence of a halogen- or hydroxy-substituted tryptophan precursor yields a novel corresponding halogen- or hydroxy-substituted nocathiacin compound which has broad spectrum antibiotic activity against Gram-positive bacteria and has in vivo efficacy in animals.

Inventors:
LI WENYING
LEET JOHN E
LAM KIN S
Application Number:
PCT/US2000/011859
Publication Date:
June 14, 2001
Filing Date:
May 02, 2000
Export Citation:
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Assignee:
SQUIBB BRISTOL MYERS CO (US)
International Classes:
C12P1/06; A61K31/7052; A61P31/04; C07H17/00; C12P17/08; C12P17/18; C12P19/60; C12P21/04; C12R1/365; (IPC1-7): C12P21/04; C12P17/14; C12P17/18
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