Title:
HEART DERIVED CELLS FOR CARDIAC REPAIR
Document Type and Number:
WIPO Patent Application WO2004019767
Kind Code:
A3
Abstract:
The present invention is drawn to compositions and methods of using the same to cardiovascular disease. The compositions of the present invention are cardiac stem cells that are c-kit/CD31<+>/CD38<+> and express telomerase reverse transcriptase.
Inventors:
SCHNEIDER MICHAEL D (US)
ENTMAN MARK (US)
OH HIDEMASA (US)
ENTMAN MARK (US)
OH HIDEMASA (US)
Application Number:
PCT/US2003/027361
Publication Date:
March 10, 2005
Filing Date:
August 29, 2003
Export Citation:
Assignee:
BAYLOR COLLEGE MEDICINE (US)
SCHNEIDER MICHAEL D (US)
ENTMAN MARK (US)
OH HIDEMASA (US)
SCHNEIDER MICHAEL D (US)
ENTMAN MARK (US)
OH HIDEMASA (US)
International Classes:
C12N5/00; C12N5/077; A61B; (IPC1-7): C12N5/00; C12N5/08
Other References:
OH, H. ET AL.: "Cardiac progenitor cells from adult myocardium: homing, differentiatin, and fusion after infarction", PNAS, vol. 100, no. 21, 14 October 2003 (2003-10-14), pages 12313 - 12318, XP002984517
OH, H. ET AL.: "Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival", PNAS, vol. 98, no. 18, 28 August 2001 (2001-08-28), pages 10308 - 10313, XP002984518
OH, H. ET AL.: "Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival", PNAS, vol. 98, no. 18, 28 August 2001 (2001-08-28), pages 10308 - 10313, XP002984518
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