Title:
HEMOSTATIC POLYMER MATERIAL KIT
Document Type and Number:
WIPO Patent Application WO/2021/225144
Kind Code:
A1
Abstract:
[Problem] To provide a safe and effective hemostatic method, blood vessel occlusion method, tissue covering method, or body fluid coagulation method, using a polymer material which is a non-biologically derived synthetic product. [Solution] A solution (pre-gel solution) is prepared, having specific pH condition and ionic strength, and containing a specific concentration of a hydrophilic polymer that may form a hydrogel by intermolecular crosslinking, and this is gelled in situ under an environment wherein blood is present, such as a bleeding site or the interior of a blood vessel.
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Inventors:
SAKAI TAKAMASA (JP)
MASUI KOSUKE (JP)
NARITA SHINICHI (JP)
KAMATA HIROYUKI (JP)
MASUI KOSUKE (JP)
NARITA SHINICHI (JP)
KAMATA HIROYUKI (JP)
Application Number:
PCT/JP2021/017403
Publication Date:
November 11, 2021
Filing Date:
May 06, 2021
Export Citation:
Assignee:
UNIV TOKYO (JP)
GELLYCLE CO LTD (JP)
GELLYCLE CO LTD (JP)
International Classes:
A61L31/14; A61L31/04; A61L31/06
Domestic Patent References:
| WO2016143647A1 | 2016-09-15 | |||
| WO2017119296A1 | 2017-07-13 | |||
| WO2007083522A1 | 2007-07-26 |
Foreign References:
| JP2013048936A | 2013-03-14 | |||
| JP2003531682A | 2003-10-28 | |||
| JP2017066150A | 2017-04-06 |
Other References:
BU, YAZHONG ET AL.: "Tetra-PEG Based hydrogel Sealants for In Vivo Visceral Hemostasis", ADVANCED MATERIALS, vol. 31, no. 28, 2019, pages e1901580, XP055872244
MATSUNAGA ET AL., MACROMOLECULES, vol. 42, no. 4, 2009, pages 1344 - 1351
MATSUNAGA ET AL., MACROMOLECULES, vol. 42, no. 4, 2009, pages 1344 - 1351
Attorney, Agent or Firm:
ONO Makoto et al. (JP)
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