Title:
HETEROAROMATIC RING DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2012/153729
Kind Code:
A1
Abstract:
The compound represented by formula
(IA)
or a pharmaceutically acceptable salt thereof is based on orexin (OX)receptor antagonist activity, is useful in the treatment and prevention of illnesses including sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependency, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, pain, gastrointestinal disease, epilepsy, inflammation, immunological disease, endocrinological related disease, and hypertension.
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Inventors:
SUZUKI RYO (JP)
FUTAMURA AYA (JP)
ABE MASAHITO (JP)
KASHIWA SHUHEI (JP)
HATTORI NOBUTAKA (JP)
NOZAWA DAI (JP)
OHTA HIROSHI (JP)
ARAKI YUKO (JP)
FUTAMURA AYA (JP)
ABE MASAHITO (JP)
KASHIWA SHUHEI (JP)
HATTORI NOBUTAKA (JP)
NOZAWA DAI (JP)
OHTA HIROSHI (JP)
ARAKI YUKO (JP)
Application Number:
PCT/JP2012/061745
Publication Date:
November 15, 2012
Filing Date:
May 08, 2012
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
SUZUKI RYO (JP)
FUTAMURA AYA (JP)
ABE MASAHITO (JP)
KASHIWA SHUHEI (JP)
HATTORI NOBUTAKA (JP)
NOZAWA DAI (JP)
OHTA HIROSHI (JP)
ARAKI YUKO (JP)
SUZUKI RYO (JP)
FUTAMURA AYA (JP)
ABE MASAHITO (JP)
KASHIWA SHUHEI (JP)
HATTORI NOBUTAKA (JP)
NOZAWA DAI (JP)
OHTA HIROSHI (JP)
ARAKI YUKO (JP)
International Classes:
A61K31/4192; C07D401/14; A61K31/422; A61K31/4245; A61K31/4439; A61K31/506; A61P1/00; A61P5/00; A61P9/12; A61P25/08; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P29/00; A61P29/02; A61P37/00; C07D403/12; C07D413/12; C07D413/14
Domestic Patent References:
| WO2010051237A1 | 2010-05-06 | |||
| WO2010044054A1 | 2010-04-22 | |||
| WO2012008549A1 | 2012-01-19 |
Foreign References:
| JP2010520206A | 2010-06-10 | |||
| JP2007522197A | 2007-08-09 |
Other References:
GATFIELD, JOHN: "Orexin Receptor Antagonists: A New Concept In CNS Disorders?", CHEMMEDCHEM, vol. 5, 2010, pages 1197 - 1214, XP009145815
See also references of EP 2708537A4
See also references of EP 2708537A4
Attorney, Agent or Firm:
ASAMURA Kiyoshi et al. (JP)
Hiroshi Asamura (JP)
Hiroshi Asamura (JP)
Download PDF:
Claims: