Title:
HETEROCYCLES USEFUL AS ANTI-CANCER AGENTS
Document Type and Number:
WIPO Patent Application WO/2017/101763
Kind Code:
A1
Abstract:
Compounds of Formula (I) are shown below, and their pharmaceutically acceptable salts, hydrates, or solvates thereof. It involves pharmaceutical compositions of these compounds, their preparation, and their utilities in treating diseases and disorders, including cancers.
Inventors:
ZHANG HANCHENG (CN)
LIU SHIFENG (CN)
LIU SHIFENG (CN)
Application Number:
PCT/CN2016/109754
Publication Date:
June 22, 2017
Filing Date:
December 13, 2016
Export Citation:
Assignee:
HANGZHOU INNOGATE PHARMA CO LTD (CN)
International Classes:
C07D471/04; A61K31/519; A61P31/12; A61P35/00; C07D519/00
Domestic Patent References:
| WO2014183520A1 | 2014-11-20 | |||
| WO2016015597A1 | 2016-02-04 | |||
| WO2014150925A2 | 2014-09-25 | |||
| WO2003062236A1 | 2003-07-31 | |||
| WO2001055148A1 | 2001-08-02 | |||
| WO2014183520A1 | 2014-11-20 |
Foreign References:
| CN105294736A | 2016-02-03 | |||
| CN101001857A | 2007-07-18 | |||
| CN1433417A | 2003-07-30 | |||
| CN105130986A | 2015-12-09 | |||
| US20060142312A1 | 2006-06-29 |
Other References:
XIE, SHAO ET AL.: "Progress in Development of Cyclin-dependent Kinase Inhibitors as Cancer Therapy.", PROGRESS IN PHARMACEUTICAL SCIENCES, vol. 39, no. 10, 31 October 2015 (2015-10-31), pages 734 - 745, XP009510889
ZHANG ZHEN-PEI, LI DE-HAI, GU QIAN-QUN, LUAN YE-PENG: "The research progress of selective histone deacetylase inhibitors.", CHINESE JOURNAL OF MEDICINAL CHEMISTRY, vol. 23, no. 4, 31 August 2013 (2013-08-31), pages 321 - 330, XP 009510895, ISSN: 1005-0108
NATURE REVIEWS, vol. 9, 2009, pages 153 - 166
MOL. CANCER RES., vol. 5, October 2007 (2007-10-01), pages 981
XIE, SHAO ET AL., PROGRESS IN PHARMACEUTICAL SCIENCES, vol. 39, no. 10, 31 October 2015 (2015-10-31), pages 734 - 745
J. MED. CHEM., vol. 48, no. 7, 2005, pages 2388 - 2406
ZHANG ZHEN-PEI, LI DE-HAI, GU QIAN-QUN, LUAN YE-PENG: "The research progress of selective histone deacetylase inhibitors.", CHINESE JOURNAL OF MEDICINAL CHEMISTRY, vol. 23, no. 4, 31 August 2013 (2013-08-31), pages 321 - 330, XP 009510895, ISSN: 1005-0108
NATURE REVIEWS, vol. 9, 2009, pages 153 - 166
MOL. CANCER RES., vol. 5, October 2007 (2007-10-01), pages 981
XIE, SHAO ET AL., PROGRESS IN PHARMACEUTICAL SCIENCES, vol. 39, no. 10, 31 October 2015 (2015-10-31), pages 734 - 745
J. MED. CHEM., vol. 48, no. 7, 2005, pages 2388 - 2406
Attorney, Agent or Firm:
XU & PARTNERS,LLC. (CN)
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