Title:
HETEROCYCLIC COMPOUND AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/242743
Kind Code:
A1
Abstract:
Provided is a heterocyclic compound having the structure as shown in formula (I). Experimental results show that a specific modification group is selected, so that the heterocyclic compound has a significant increase in the activity as a TRβ agonist compared with the prior art, has higher TRβ selectivity, can be used for treating and/or preventing diseases caused by thyroid hormone regulation, and has lower side effects.
Inventors:
DENG ZHOU (CN)
ZHOU YOU (CN)
SHAN SONG (CN)
YE ZHIYONG (CN)
ZHANG KUN (CN)
PAN DESI (CN)
LI ZHIBIN (CN)
LU XIANPING (CN)
ZHOU YOU (CN)
SHAN SONG (CN)
YE ZHIYONG (CN)
ZHANG KUN (CN)
PAN DESI (CN)
LI ZHIBIN (CN)
LU XIANPING (CN)
Application Number:
PCT/CN2022/094094
Publication Date:
November 24, 2022
Filing Date:
May 20, 2022
Export Citation:
Assignee:
SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN)
International Classes:
C07D403/14; A61K31/519; A61K31/53; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P5/14; A61P9/10; A61P35/00; C07D401/14; C07D487/04
Domestic Patent References:
| WO2021018226A1 | 2021-02-04 | |||
| WO2021041237A1 | 2021-03-04 | |||
| WO2020227549A1 | 2020-11-12 | |||
| WO2020169069A1 | 2020-08-27 |
Foreign References:
| CN112300133A | 2021-02-02 |
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
Download PDF:
Previous Patent: SEAMLESS STEEL TUBE RESISTANT TO CARBON DIOXIDE CORROSION AND MANUFACTURING METHOD THEREFOR
Next Patent: BATTERY
Next Patent: BATTERY