Title:
HETEROCYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2009/119528
Kind Code:
A1
Abstract:
Disclosed is a compound having an inhibitory activity on the intake of a monoamine neurotransmitter. Specifically disclosed is a compound represented by formula (I) [wherein each symbol is as defined in the description] or a salt thereof. (I)
Inventors:
HONDA EIJI (JP)
Application Number:
PCT/JP2009/055716
Publication Date:
October 01, 2009
Filing Date:
March 23, 2009
Export Citation:
Assignee:
TAKEDA PHARMACEUTICAL (JP)
HONDA EIJI (JP)
HONDA EIJI (JP)
International Classes:
C07D243/08; A61K31/551; A61K31/5517; A61P25/18; A61P25/22; A61P25/24; A61P43/00; C07D243/10; C07D403/04; C07D405/04; C07D487/04; C07D487/08
Domestic Patent References:
| WO2007028654A1 | 2007-03-15 | |||
| WO2008002820A2 | 2008-01-03 | |||
| WO2001002372A1 | 2001-01-11 | |||
| WO2005111029A1 | 2005-11-24 | |||
| WO2005100349A2 | 2005-10-27 | |||
| WO2005099711A1 | 2005-10-27 | |||
| WO2005082895A1 | 2005-09-09 | |||
| WO2004089937A1 | 2004-10-21 |
Foreign References:
| US20020052360A1 | 2002-05-02 | |||
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| US20070010529A1 | 2007-01-11 | |||
| EP1518855A1 | 2005-03-30 | |||
| US20020183324A1 | 2002-12-05 |
Other References:
MA, X. ET AL.: "QSAR study of substituted 1-(2-naphthyl)-1H-pyrazole-5-carboxylamide factor Xa (fXa) inhibitors", MOLECULAR SIMULATION, vol. 33, no. 14-15, 2007, pages 1213 - 1222
JIA, Z.J. ET AL.: "l-(2-Naphthyl)-lH-pyrazole-5- carboxylamides as potent factor Xa inhibitors. Part 2: A survey of P4 motifs", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 5, 2004, pages 1221 - 1227
CHAMMACHE, M. ET AL.: "Reactivity of 7-phenyl-1, 4-diazepin-5-one", BULLETIN DES SOCIETES CHIMIQUES BELGES, vol. 102, no. 2, 1993, pages 89 - 98
TATEE, T. ET AL.: "Isoxazole derivatives as centrally acting muscle relaxants. III. Synthesis and activity of conformationally restricted analogs", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 35, no. 9, 1987, pages 3676 - 3690
TAKAO YAMAZAKI ET AL.: "N, N'-Dihomoveratryl- Methylimino-Dicarboxylic Acid Amide-Rui no Isoquinoline Heikan", JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 79, no. 9, 1959, pages 1219 - 1222
JIA, Z.J. ET AL.: "l-(2-Naphthyl)-lH-pyrazole-5- carboxylamides as potent factor Xa inhibitors. Part 2: A survey of P4 motifs", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 14, no. 5, 2004, pages 1221 - 1227
CHAMMACHE, M. ET AL.: "Reactivity of 7-phenyl-1, 4-diazepin-5-one", BULLETIN DES SOCIETES CHIMIQUES BELGES, vol. 102, no. 2, 1993, pages 89 - 98
TATEE, T. ET AL.: "Isoxazole derivatives as centrally acting muscle relaxants. III. Synthesis and activity of conformationally restricted analogs", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 35, no. 9, 1987, pages 3676 - 3690
TAKAO YAMAZAKI ET AL.: "N, N'-Dihomoveratryl- Methylimino-Dicarboxylic Acid Amide-Rui no Isoquinoline Heikan", JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, vol. 79, no. 9, 1959, pages 1219 - 1222
Attorney, Agent or Firm:
TAKASHIMA, HAJIME (JP)
Takashima 1 (JP)
Takashima 1 (JP)
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