Title:
HETEROCYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12D
Document Type and Number:
WIPO Patent Application WO/2022/194191
Kind Code:
A1
Abstract:
Provided are heterocyclics as inhibitors of KRAS G12D, in particular a compound of Formula I or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising said compound that are useful for treatment of KRAS G12D mediated diseases and conditions such as cancer.
Inventors:
WANG ZHAOYIN (CA)
ZHAO XINSUO (CN)
CHAI YONGSHUAI (CN)
YAO GUORUI (US)
LI NANXIN (US)
ZHAO XINSUO (CN)
CHAI YONGSHUAI (CN)
YAO GUORUI (US)
LI NANXIN (US)
Application Number:
PCT/CN2022/081086
Publication Date:
September 22, 2022
Filing Date:
March 16, 2022
Export Citation:
Assignee:
GUANGDONG NEWOPP BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
A61K31/4745; C07D401/14; A61K31/517; A61P35/00; C07D403/14; C07D413/14
Domestic Patent References:
| WO2018218070A2 | 2018-11-29 | |||
| WO2020146613A1 | 2020-07-16 | |||
| WO2021031952A1 | 2021-02-25 | |||
| WO2021041671A1 | 2021-03-04 | |||
| WO2020108613A1 | 2020-06-04 | |||
| WO2013072694A1 | 2013-05-23 |
Attorney, Agent or Firm:
SHANGHAI ZHIXIN PATENT AGENT LTD. (CN)
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