Title:
HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT
Document Type and Number:
WIPO Patent Application WO/2020/181232
Kind Code:
A8
Abstract:
The present invention provides heterocyclic compounds that bind to the ubiquitously expressed E3 ligase protein cereblon (CRBN) and their use for the treatment of abnormal cellular proliferation in a human or other host. The present invention also provides compounds that can be used as synthetic intermediates in the synthesis of bifunctional compounds used for targeted protein degradation.
Inventors:
NASVESCHUK CHRISTOPHER (US)
NORCROSS ROGER (CH)
DEY FABIAN (CH)
GOERGLER ANNICK (CH)
KUSZNIR ERIC (CH)
NORCROSS ROGER (CH)
DEY FABIAN (CH)
GOERGLER ANNICK (CH)
KUSZNIR ERIC (CH)
Application Number:
PCT/US2020/021491
Publication Date:
August 26, 2021
Filing Date:
March 06, 2020
Export Citation:
Assignee:
C4 THERAPEUTICS INC (US)
International Classes:
C07D401/04; A61K31/335
Attorney, Agent or Firm:
BELLOWS, Brent, R. et al. (US)
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