Title:
HETEROCYCLIC CONDENSED BENZOIC ACID DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO/1994/008995
Kind Code:
A1
Abstract:
Compounds of formula (I), wherein formula (I) consists of formulae (I-1) to (I-4), and pharmaceutically acceptable salts thereof, and the use of a compound of formula (I) or a pharmaceutically acceptable salt thereof, (I-1), (I-2), (I-3), (I-4) and their use as pharmaceuticals in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders. The compounds are 5-HT4 receptor antagonists.
Inventors:
GASTER LARAMIE MARY (GB)
MULHOLLAND KEITH RAYMOND (GB)
MULHOLLAND KEITH RAYMOND (GB)
Application Number:
PCT/EP1993/002809
Publication Date:
April 28, 1994
Filing Date:
October 12, 1993
Export Citation:
Assignee:
SMITHKLINE BEECHAM PLC (GB)
GASTER LARAMIE MARY (GB)
MULHOLLAND KEITH RAYMOND (GB)
GASTER LARAMIE MARY (GB)
MULHOLLAND KEITH RAYMOND (GB)
International Classes:
C07D333/52; A61K31/335; A61K31/35; A61K31/352; A61K31/38; A61K31/381; A61K31/382; A61K31/443; A61K31/4433; A61K31/445; A61P1/00; A61P9/00; A61P43/00; C07D311/80; C07D313/12; C07D335/06; C07D405/12; C07D409/12; C07D413/12; (IPC1-7): C07D405/12; A61K31/34; A61K31/35; A61K31/38; A61K31/445; C07D307/79; C07D311/78; C07D333/54; C07D409/12; C07D413/12
Domestic Patent References:
| WO1993016072A1 | 1993-08-19 | |||
| WO1993005038A1 | 1993-03-18 | |||
| WO1993002677A1 | 1993-02-18 |
Foreign References:
| EP0270342A2 | 1988-06-08 | |||
| EP0496064A1 | 1992-07-29 | |||
| EP0234872A1 | 1987-09-02 | |||
| EP0493041A2 | 1992-07-01 | |||
| EP0407137A2 | 1991-01-09 | |||
| EP0445862A2 | 1991-09-11 | |||
| EP0501322A1 | 1992-09-02 |
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