Title:
HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/016518
Kind Code:
A1
Abstract:
Disclosed are a compound as represented by general formula (I) or a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof and an intermediate thereof; and the use thereof in AR-related diseases such as cancer.
B-L-K (I)
Inventors:
ZHANG CHEN (CN)
LIAO YUTING (CN)
CHEN XIAOGANG (CN)
XU JINXIONG (CN)
YU YAN (CN)
TANG PINGMING (CN)
GAO QIU (CN)
ZHAO JUNBIN (CN)
LI YUPENG (CN)
CHENG XINFAN (CN)
ZHU GUOZHI (CN)
YE FEI (CN)
LI YAO (CN)
NI JIA (CN)
YAN PANGKE (CN)
LIAO YUTING (CN)
CHEN XIAOGANG (CN)
XU JINXIONG (CN)
YU YAN (CN)
TANG PINGMING (CN)
GAO QIU (CN)
ZHAO JUNBIN (CN)
LI YUPENG (CN)
CHENG XINFAN (CN)
ZHU GUOZHI (CN)
YE FEI (CN)
LI YAO (CN)
NI JIA (CN)
YAN PANGKE (CN)
Application Number:
PCT/CN2022/111743
Publication Date:
February 16, 2023
Filing Date:
August 11, 2022
Export Citation:
Assignee:
SICHUAN HAISCO PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D401/14; A61K31/444; A61K31/496; A61K31/517; A61P35/00; C07D417/14; C07D471/04; C07D471/08; C07D471/10
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Other References:
DATABASE REGISTRY ANONYMOUS : " Tricyclo[3.3.1.13,7]decane-1-acetic acid, 3-hydroxy-, [3-[2-[(2-methoxyphenyl)amino]-2-oxoethyl]-1,2,4-oxadiazol-5-yl]methyl ester (CA INDEX NAME)", XP055886189, retrieved from STN
DATABASE REGISTRY ANONYMOUS : "1-Piperazineacetamide, N-phenyl-4-(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)- (CA INDEX NAME)", XP055886190, retrieved from STN
NAT. COMMUN., vol. 13, 2022, pages 815
DATABASE REGISTRY ANONYMOUS : "1-Piperazineacetamide, N-phenyl-4-(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)- (CA INDEX NAME)", XP055886190, retrieved from STN
NAT. COMMUN., vol. 13, 2022, pages 815
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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