Title:
HETEROCYCLIC METHYL SULFONE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2005/000798
Kind Code:
A1
Abstract:
A compound which inhibits the secretion and production of β-amyloid protein. It is a compound represented by the general formula (1): (wherein R1 represents an optionally substituted heterocyclic group; R2 represents an optionally substituted cyclic hydrocarbon group or optionally substituted heterocyclic group; R3 represents an optionally substituted cyclic hydrocarbon group or optionally substituted heterocyclic group; R4 represents hydrogen or C1-6 alkyl; and X represents -S-, -SO-, or -SO2-), an N-oxide thereof, an S-oxide thereof, a salt thereof, or a solvate of any of these. Also provided is a medicine containing any of these.
Inventors:
KUBOTA HIDEKI (JP)
YASUKOUCHI TAKANORI (JP)
MIYAUCHI SATORU (JP)
MOTOKI KAYOKO (JP)
SAITO MASANORI (JP)
IIMORI HITOSHI (JP)
YASUKOUCHI TAKANORI (JP)
MIYAUCHI SATORU (JP)
MOTOKI KAYOKO (JP)
SAITO MASANORI (JP)
IIMORI HITOSHI (JP)
Application Number:
PCT/JP2004/009132
Publication Date:
January 06, 2005
Filing Date:
June 29, 2004
Export Citation:
Assignee:
DAIICHI SEIYAKU CO (JP)
KUBOTA HIDEKI (JP)
YASUKOUCHI TAKANORI (JP)
MIYAUCHI SATORU (JP)
MOTOKI KAYOKO (JP)
SAITO MASANORI (JP)
IIMORI HITOSHI (JP)
KUBOTA HIDEKI (JP)
YASUKOUCHI TAKANORI (JP)
MIYAUCHI SATORU (JP)
MOTOKI KAYOKO (JP)
SAITO MASANORI (JP)
IIMORI HITOSHI (JP)
International Classes:
A61P25/28; A61P43/00; C07C317/14; C07D213/30; C07D233/60; C07D277/26; (IPC1-7): C07C317/14; C07D239/26; C07D211/20; C07D211/76; C07D213/87; C07D213/83; C07D213/48; C07D213/79; C07D213/81; C07D213/75; C07D213/73; C07D213/76; C07D213/77; C07D213/57; C07D213/36; C07D213/80; C07D213/89; C07D213/61; C07D213/74; C07D213/42; C07D213/40; C07D213/56; C07D213/53; C07D213/82; C07D213/32; C07D213/65; C07D213/70; C07D213/71; C07D213/55; C07D213/50; C07D213/38; C07D233/60; C07D235/06; C07D311/18; C07D277/26; C07D309/04; C07D405/06; C07D401/06; C07D405/04; C07D401/12; C07D405/12; C07D409/12; C07D401/04; C07D413/04; C07D417/12; C07D413/12; A61K31/10; A61K31/505; A61K31/4409; A61K31/541; A61K31/496; A61K31/5377; A61K31/455; A61K31/4402; A61K31/44; A61K31/4406; A61K31/444; A61K31/4545; A61K31/4164; A61K31/352; A61K31/426; A61K31/351; A61K31/4433; A61K31/443; A61K31/4436; A61K31/4439; A61K31/506; A61K31/366; A61K31/37; A61K31/382; A61P25/28; A61P43/00
Domestic Patent References:
| WO2004017977A2 | 2004-03-04 | |||
| WO2004031138A1 | 2004-04-15 | |||
| WO2003055850A1 | 2003-07-10 | |||
| WO2002081433A1 | 2002-10-17 | |||
| WO1996041799A1 | 1996-12-27 |
Foreign References:
| JPH0656780A | 1994-03-01 | |||
| JPH0625168A | 1994-02-01 | |||
| JPS5533473A | 1980-03-08 | |||
| US4116665A | 1978-09-26 |
Other References:
TABAKOVIC I. ET AL.: "The alkylation of coumarin at C-3 of 4-hydroxycoumarin", ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, vol. 29, no. 2, 1997, pages 223 - 226, XP002981435
See also references of EP 1640366A4
See also references of EP 1640366A4
Attorney, Agent or Firm:
The, Patent Corporate Body Aruga Patent Office (NIHONBASHININGYOCHO 1-CHOME CHUO-K, Tokyo 13, JP)
Download PDF:
Previous Patent: AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME
Next Patent: PROCESS FOR PREPARING POLYMORPHIC FORM (I) OF MODAFINIL
Next Patent: PROCESS FOR PREPARING POLYMORPHIC FORM (I) OF MODAFINIL