Title:
HETEROLOGOUS PROTECTION INDUCED BY IMMUNIZATION WITH INVAPLEX VACCINE
Document Type and Number:
WIPO Patent Application WO2002094190
Kind Code:
A3
Abstract:
In this application is described a composition, Invaplex, derived from a gram negative bacteria for use in generating an immune response in a subject against one ore more heterologous species or strains of gram-negative bacteria.
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Inventors:
OAKS EDWIN V (US)
TURBYFILL KEVIN R (US)
TURBYFILL KEVIN R (US)
Application Number:
PCT/US2002/016029
Publication Date:
December 11, 2003
Filing Date:
May 17, 2002
Export Citation:
Assignee:
US ARMY (US)
OAKS EDWIN V (US)
TURBYFILL KEVIN R (US)
OAKS EDWIN V (US)
TURBYFILL KEVIN R (US)
International Classes:
A61K39/104; A61K39/002; A61K39/02; A61K39/106; A61K39/112; A61K39/116; A61K39/118; A61P31/04; (IPC1-7): A61K39/385; A61K39/02; A61K39/116; A61K39/108; A61K39/112; C07K1/00; G01N33/53
Foreign References:
| US6277379B1 | 2001-08-21 | |||
| US6245892B1 | 2001-06-12 |
Other References:
TURBYFILL ET AL.: "Identification of epitope and surface-exposed domains of shigella flexneri invasion plasmid antigen D (IpaD)", INFECTION AND IMMUNITY, vol. 66, no. 5, May 1998 (1998-05-01), pages 1999 - 2006, XP002141130
BARZU ET AL.: "Induction of a local anti-IpaC antibody response in mice by use of a shigella flexneri 2a vaccine candidate: implications for use of IpaC as a protein carrier", INFECTION AND IMMUNITY, vol. 64, no. 4, April 1996 (1996-04-01), pages 1190 - 1196, XP002141131
BARZU ET AL.: "Induction of a local anti-IpaC antibody response in mice by use of a shigella flexneri 2a vaccine candidate: implications for use of IpaC as a protein carrier", INFECTION AND IMMUNITY, vol. 64, no. 4, April 1996 (1996-04-01), pages 1190 - 1196, XP002141131
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