HETROCYCLIC MODULATORS OF NUCLEAR RECEPTORS

Title:

HETROCYCLIC MODULATORS OF NUCLEAR RECEPTORS

Document Type and Number:

WIPO Patent Application WO2003060078

Kind Code:

A9

Abstract:

Compounds, compositions and methods for modulating the activity of nuclear receptors are provided. In particular, heterocyclic compounds are provided for modulating the activity of farnesoid X receptor (FXR), liver X receptor (LXR) and/or orphan nuclear receptors. In certain embodiments, the compounds are thiazolidinone derivatives.

Inventors:

MARTIN RICHARD (US)
FLATT BRENTON TODD (US)
WANG TIE-LIN (US)
KAHL JEFFERY DEAN (US)

Application Number:

PCT/US2002/041224

Publication Date:

February 19, 2004

Filing Date:

December 20, 2002

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Assignee:

X CEPTOR THERAPEUTICS INC (US)
MARTIN RICHARD (US)
FLATT BRENTON TODD (US)
WANG TIE-LIN (US)
KAHL JEFFERY DEAN (US)

International Classes:

C07D277/20; C07D277/64; C07D417/04; C07D417/06; C07D417/14; C07D513/04; C07D521/00; (IPC1-7): C12N/

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