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Title:
HIGH-PERFORMANCE MICRO-NEEDLE ARRAY
Document Type and Number:
WIPO Patent Application WO/2021/241486
Kind Code:
A1
Abstract:
Provided is a micro-needle array of which all the fine needles can be more easily inserted into the skin regardless of the positions where the fine needles of the micro-needle array are located on a substrate. The micro-needle array comprises a substrate and a plurality of micro-needles disposed on one surface of the substrate, wherein the tip sections of the plurality of the micro-needles have height differences, and the needle lengths are 80-2,000 μm inclusive. It is desirable that the height differences of the plurality of micro-needles be based on the protrusions and recesses of the substrate.

Inventors:
QUAN YING-SHU (JP)
LI YING-ZHE (JP)
KAJIYAMA KENJI (JP)
SAITO MIO (JP)
YAMASHITA HIROFUMI (JP)
KAMIYAMA FUMIO (JP)
Application Number:
PCT/JP2021/019584
Publication Date:
December 02, 2021
Filing Date:
May 24, 2021
Export Citation:
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Assignee:
COSMED PHARMACEUTICAL CO LTD (JP)
International Classes:
A61M37/00
Domestic Patent References:
WO2016114213A12016-07-21
WO2017208962A12017-12-07
WO2018124290A12018-07-05
Foreign References:
US20140296683A12014-10-02
US20120004614A12012-01-05
JP2009240410A2009-10-22
JP2019219179A2019-12-26
JP2009273872A2009-11-26
JP2010029634A2010-02-12
JP2017074196A2017-04-20
JP2016175853A2016-10-06
JP2015109963A2015-06-18
JP2017047075A2017-03-09
JP2017185162A2017-10-12
JP2014028108A2014-02-13
JP2003238347A2003-08-27
JP2017137311A2017-08-10
JP2018108375A2018-07-12
Other References:
YING-SHU QUANFUMIO KAMIYAMA: "The Course of Productization of Micro-needle", THE ARCHIVES OF PRACTICAL PHARMACY, THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN, vol. 69, no. 4, July 2009 (2009-07-01), pages 272 - 276
G. YA ET AL.: "Evaluation needle length and density of microneedle arrays in the pretreatment of skin for transdermal drug delivery", INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 391, 2010, pages 7 - 12, XP027018863
J. PHARMACEUTICS, vol. 480, 2015, pages 152 - 157
Attorney, Agent or Firm:
MIYAZAKI & METSUGI (JP)
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