Title:
HIGHER FATTY ACID DERIVATIVE MARKED WITH TECHNETIUM-99M
Document Type and Number:
WIPO Patent Application WO/2015/103946
Kind Code:
A1
Abstract:
Disclosed is a higher fatty acid derivative marked with Technetium-99m, being a long chain fatty acid metabolism drug. The long chain fatty acid metabolism drug introduces sulfonyl and thiophen ring to long chain fatty acid to eventually decrease liposolubility of molecules, increase intake of the drug in the myocardium, and extend the retention time of the drug in the myocardium.
Inventors:
ZHANG HUABEI (CN)
XUE TIAN (CN)
LI XIANG (CN)
XUE TIAN (CN)
LI XIANG (CN)
Application Number:
PCT/CN2015/000087
Publication Date:
July 16, 2015
Filing Date:
February 09, 2015
Export Citation:
Assignee:
UNIV BEIJING NORMAL (CN)
International Classes:
C07F13/00; A61K51/00; A61K103/10
Domestic Patent References:
| WO1997047328A1 | 1997-12-18 | |||
| WO1991018908A1 | 1991-12-12 |
Foreign References:
| CN102311459A | 2012-01-11 |
Other References:
ZENG, HUAHUI ET AL.: "Synthesis and biological evaluation of fatty acids conjugates bearing cyclopentadienyl-donors incorporated [99mTc/Re(CO)3]+ for myocardical imaging.", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 72, 22 November 2013 (2013-11-22), pages 10 - 17
ZENG, HUAHUI ET AL.: "Preliminary studies of a novel cyclopentadienyl tricarbonyl technetium-99m fatty acid derivative for myocardical imaging.", J. LABEL COMPD. RADIOPHARM, vol. 56, 7 December 2012 (2012-12-07), pages 1 - 5
ZENG, HUAHUI ET AL.: "Preliminary studies of a novel cyclopentadienyl tricarbonyl technetium-99m fatty acid derivative for myocardical imaging.", J. LABEL COMPD. RADIOPHARM, vol. 56, 7 December 2012 (2012-12-07), pages 1 - 5
Attorney, Agent or Firm:
BEIJING FINDTO ATTOORNEYS AT LAW (CN)
北京方韬法业专利代理事务所 (CN)
北京方韬法业专利代理事务所 (CN)
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