HIGHLY WATER-SOLUBLE METALLOPROTEINASE INHIBITOR

Title:

HIGHLY WATER-SOLUBLE METALLOPROTEINASE INHIBITOR

Document Type and Number:

WIPO Patent Application WO/1996/033968

Kind Code:

A1

Abstract:

Novel compounds represented by general formula (I), stereoisomers thereof, pharmaceutically acceptable salts, and solvates thereof, processes for the preparation thereof, a matrix metalloproteinase inhibitor comprising as the active ingredient at least one member selected among the above compounds, intermediates for preparing the compounds represented by general formula (I), and a process for preparing the same.

Inventors:

FUJISAWA TETSUNORI (JP)
ODAKE SHINJIRO (JP)
MORITA YASUO (JP)
HONGO TOMOKO (JP)
ITO HAJIME (JP)
YASUDA JUNKO (JP)
SUDA EIKO (JP)
IGETA KATSUHIRO (JP)
MORIKAWA TADANORI (JP)

Application Number:

PCT/JP1996/001135

Publication Date:

October 31, 1996

Filing Date:

April 25, 1996

Export Citation:

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Assignee:

FUJI YAKUHIN KOGYO KK (JP)
FUJISAWA TETSUNORI (JP)
ODAKE SHINJIRO (JP)
MORITA YASUO (JP)
HONGO TOMOKO (JP)
ITO HAJIME (JP)
YASUDA JUNKO (JP)
SUDA EIKO (JP)
IGETA KATSUHIRO (JP)
MORIKAWA TADANORI (JP)

International Classes:

A61K31/165; C07C239/06; C07C259/06; C07C279/14; C07C279/16; C07C305/24; C07C309/61; C07C323/60; C07F9/12; (IPC1-7): C07C237/20; C07C237/22; C07C259/06; C07C309/61; C07D521/00; C07F7/18; C07F9/09; A61K31/165; A61K31/33; A61K31/66; A61K31/695; C12N9/99

Domestic Patent References:

WO1994002446A1	1994-02-03
WO1995022966A1	1995-08-31
WO1995019956A1	1995-07-27

Foreign References:

JPH06506445A	1994-07-21
JPH0687813A	1994-03-29

Other References: