Title:
HOLOGRAPHIC CHARACTERIZATION OF PROTEIN AGGREGATES
Document Type and Number:
WIPO Patent Application WO/2017/139279
Kind Code:
A3
Abstract:
Systems and methods for holographic characterization of protein aggregates. Size and refractive index of individual aggregates in a solution can be determined. Information regarding morphology and porosity can be extracted from holographic data.
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Inventors:
GRIER DAVID G (US)
WARD MICHAEL D (US)
ZHONG XIAO (US)
WANG CHEN (US)
PHILIPS LAURA A (US)
RUFFNER DAVID B (US)
CHEONG FOOK CHIONG (US)
WARD MICHAEL D (US)
ZHONG XIAO (US)
WANG CHEN (US)
PHILIPS LAURA A (US)
RUFFNER DAVID B (US)
CHEONG FOOK CHIONG (US)
Application Number:
PCT/US2017/016857
Publication Date:
October 26, 2017
Filing Date:
February 07, 2017
Export Citation:
Assignee:
UNIV NEW YORK (US)
International Classes:
G01N15/02; G01B9/02; G01N15/10; G01N21/41; G01P5/20; G03H1/08
Foreign References:
| US20140333935A1 | 2014-11-13 | |||
| US20140177932A1 | 2014-06-26 | |||
| US20150062587A1 | 2015-03-05 | |||
| US20040072372A1 | 2004-04-15 |
Other References:
MEAKIN: "Fractal Aggregates", ADVANCES IN COLLOID AND INTERFACE SCIENCE, vol. 28, 1988, pages 249 - 331, XP055574701, Retrieved from the Internet [retrieved on 20170524]
Attorney, Agent or Firm:
MARTIN, Matthew E. et al. (US)
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