Title:
HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2020/045971
Kind Code:
A1
Abstract:
The present invention relates to: human-derived Lactobacillus fermentum MG4231 or Lactobacillus fermentum MG4244; and a pharmaceutical composition, a food composition, a quasi-drug composition and a health functional food for preventing or treating obesity-related diseases, all of which comprise same as an active ingredient. A lactobacillus fermentum MG4231 strain or MG4244 strain of the present invention exhibits an anti-obesity activity for inhibiting a lipase enzyme activity, inhibiting preadipocyte differentiation and inhibiting triglyceride accumulation, has an excellent ability to form colonies on the epithelial cells of a digestive tract by means of an excellent self-aggregation ability, and has resistance to acidity and bile salts, thereby being variously usable as a pharmaceutical composition, a food composition, a quasi-drug composition and a health functional food for the purpose of treating and preventing obesity-related diseases.
Inventors:
PAEK NAM SOO (KR)
KANG CHANG HO (KR)
KANG CHANG HO (KR)
Application Number:
PCT/KR2019/010961
Publication Date:
March 05, 2020
Filing Date:
August 27, 2019
Export Citation:
Assignee:
MEDIOGEN (KR)
International Classes:
C12N1/20; A23L33/135; A61K35/747; A61P3/04; C12R1/225
Foreign References:
| KR20050010451A | 2005-01-27 | |||
| KR20010106068A | 2001-11-29 | |||
| KR101981333B1 | 2019-05-23 |
Other References:
DAHIYA, D. K. ET AL.: "Conjugated linoleic acid enriched skim milk prepared with Lactobacillus fermentum DDRI27 endorsed antiobesity in mice", FUTURE MICROBIOLOGY, vol. 13, no. 9, 10 April 2018 (2018-04-10), pages 1 - 14
DAHIYA, D. K. ET AL.: "EVALUATION OF SURVIVAL, FREE RADICAL SCAVENGING AND HUMAN ENTEROCYTE ADHERENCE POTENTIAL OF LACTOBACILLI WITH ANTI-OBESITY AND ANTI-INFLAMMATORY CLA ISOMER-PRODUCING ATTRIBUTES", JOURNAL OF FOOD PROCESSING AND PRESERVATION, vol. 39, 2015, pages 2866 - 2877, XP055697452
DAHIYA, D. K. ET AL.: "EVALUATION OF SURVIVAL, FREE RADICAL SCAVENGING AND HUMAN ENTEROCYTE ADHERENCE POTENTIAL OF LACTOBACILLI WITH ANTI-OBESITY AND ANTI-INFLAMMATORY CLA ISOMER-PRODUCING ATTRIBUTES", JOURNAL OF FOOD PROCESSING AND PRESERVATION, vol. 39, 2015, pages 2866 - 2877, XP055697452
Attorney, Agent or Firm:
KIM, Dong Jin (KR)
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