Title:
HUMAN FGF-23 FLUORESCENCE IMMUNOCHROMATOGRAPHIC TEST PAPER AND HUMAN FGF-23 FLUORESCENCE IMMUNOCHROMATOGRAPHIC TEST KIT
Document Type and Number:
WIPO Patent Application WO/2021/128065
Kind Code:
A1
Abstract:
Human FGF-23 fluorescence immunochromatographic test paper and a human FGF-23 fluorescence immunochromatographic test kit. The test paper comprises: a substrate (H), and a sample pad (A), a fluorescent microsphere pad (B), a blood filtering pad (C), a reaction film (D), and a water absorbing pad (G) which are provided on the substrate (H) in sequence in a contact manner along a chromatography direction of a sample to be tested. The reaction film (D) is separately provided with a test region (E) and a quality control region (F). The fluorescent microsphere pad (B) is coated with a first antibody (1) of human FGF-23 which is labeled with a fluorescent microsphere and specifically binds to the human FGF-23 of the sample to be tested and a third antibody (6) which is labeled with a fluorescent microsphere and used for quality control. The test region (E) is coated with a second antibody (7) of human FGF-23 which specifically binds to the human FGF-23 of the sample to be tested. The quality control region (F) is coated with a fourth antibody (8) for quality control. The fluorescence immunochromatographic test paper can solve the technical defects of low specificity and poor sensitivity of the existing human FGF-23 protein test kits.
Inventors:
GUO ZHICHENG (CN)
Application Number:
PCT/CN2019/128332
Publication Date:
July 01, 2021
Filing Date:
December 25, 2019
Export Citation:
Assignee:
GUANGZHOU PHICON BIOTECH CO LTD (CN)
International Classes:
G01N33/577
Domestic Patent References:
| WO2018221544A1 | 2018-12-06 |
Foreign References:
| CN104237517A | 2014-12-24 | |||
| US20050106755A1 | 2005-05-19 | |||
| CN105968208A | 2016-09-28 | |||
| CN105606814A | 2016-05-25 | |||
| CN103180733A | 2013-06-26 | |||
| CN107632159A | 2018-01-26 | |||
| CN1639193A | 2005-07-13 | |||
| CN107255726A | 2017-10-17 |
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW (CN)
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