HUMAN GLP-1 POLYPEPTIDE VARIANT AND APPLICATION THEREOF

Title:

HUMAN GLP-1 POLYPEPTIDE VARIANT AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/143515

Kind Code:

A1

Abstract:

The present application provides a human GLP-1 polypeptide variant. A fusion protein or an immunoconjugate constructed by using the human GLP-1 polypeptide variant can be used for preventing and/or treating GLP-1 related metabolic diseases or disorders.

Inventors:

XU TING (CN)
JIN YUHAO (CN)
WANG XIAOXIAO (CN)
WANG PILIN (CN)
LI QIAN (CN)

Application Number:

PCT/CN2021/141606

Publication Date:

July 07, 2022

Filing Date:

December 27, 2021

Export Citation:

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Assignee:

SUZHOU ALPHAMAB CO LTD (CN)

International Classes:

C07K14/605; A61K38/26; A61P3/04; A61P3/10; C07K19/00; C12N15/11; C12N15/63

Domestic Patent References:

WO2018115401A1

2018-06-28

Foreign References:

US20200384119A1	2020-12-10
CN101208099A	2008-06-25
CN110865129A	2020-03-06
US20120129768A1	2012-05-24
CN102093475A	2011-06-15
CN102363633A	2012-02-29
CN108699120A	2018-10-23

Attorney, Agent or Firm:

SHANGHAI DIANSHI PARTNERS, P.C. (CN)

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