Title:
HUMAN POLYPEPTIDES ENCODED BY POLYNUCLEOTIDES AND METHODS OF THEIR USE
Document Type and Number:
WIPO Patent Application WO2004035732
Kind Code:
A3
Abstract:
The invention provides novel polynucleotides, related polypeptides related nucleic acid and polypeptide compositions, and related modulators, such as antibodies and small molecule modulators. The invention also provides methods to make and use these polynucleotides, polypeptides, related compositions, and modulators. These methods include diagnostic, prophylactic and therapeutic applications. The compositions and methods of the invention are useful in treating proliferative disorders, e.g., cancers, and inflammatory, immune, bacterial, and viral disorders.
Inventors:
WILLIAMS LEWIS T (US)
CHU KETING (US)
LEE ERNESTINE (US)
HESTIR KEVIN (US)
BEAURANG PIERRE ALVARO (US)
BEHRENS DIRK (US)
HALENBECK ROBERT FORGAN (US)
HUANG MIN MEI (US)
KOTHAKOTA SRINIVAS (US)
HAISHAN LIN (US)
LINNEMANN THOMAS (US)
PIERCE KRISTEN (US)
WANG YAN (US)
WONG JUSTIN G P (US)
WU GE (US)
ZHANG HONGBING (US)
CHU KETING (US)
LEE ERNESTINE (US)
HESTIR KEVIN (US)
BEAURANG PIERRE ALVARO (US)
BEHRENS DIRK (US)
HALENBECK ROBERT FORGAN (US)
HUANG MIN MEI (US)
KOTHAKOTA SRINIVAS (US)
HAISHAN LIN (US)
LINNEMANN THOMAS (US)
PIERCE KRISTEN (US)
WANG YAN (US)
WONG JUSTIN G P (US)
WU GE (US)
ZHANG HONGBING (US)
Application Number:
PCT/US2003/026780
Publication Date:
January 26, 2006
Filing Date:
August 28, 2003
Export Citation:
Assignee:
FIVE PRIME THERAPEUTICS INC (US)
WILLIAMS LEWIS T (US)
CHU KETING (US)
LEE ERNESTINE (US)
HESTIR KEVIN (US)
BEAURANG PIERRE ALVARO (US)
BEHRENS DIRK (US)
HALENBECK ROBERT FORGAN (US)
HUANG MIN MEI (US)
KOTHAKOTA SRINIVAS (US)
HAISHAN LIN (US)
LINNEMANN THOMAS (US)
PIERCE KRISTEN (US)
WANG YAN (US)
WONG JUSTIN G P (US)
WU GE (US)
ZHANG HONGBING (US)
WILLIAMS LEWIS T (US)
CHU KETING (US)
LEE ERNESTINE (US)
HESTIR KEVIN (US)
BEAURANG PIERRE ALVARO (US)
BEHRENS DIRK (US)
HALENBECK ROBERT FORGAN (US)
HUANG MIN MEI (US)
KOTHAKOTA SRINIVAS (US)
HAISHAN LIN (US)
LINNEMANN THOMAS (US)
PIERCE KRISTEN (US)
WANG YAN (US)
WONG JUSTIN G P (US)
WU GE (US)
ZHANG HONGBING (US)
International Classes:
C07K14/47; C12N; (IPC1-7): C07K14/00; C07H21/04; C12N1/20; C12N1/21; C12N5/10; C12N15/11; C12N15/63; C12N15/64; G01N33/50
Other References:
CANAVEZ F. ET AL: "Comparison of chimpanzee anf human leukocyte Ig-like receptor genes reveals framework and rapidly evolving genes", J. IMMUNOL., vol. 167, no. 10, 2001, pages 5786 - 2794, XP002993003
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