Title:
HUMAN T CELL DERIVED FROM T CELL-DERIVED INDUCED PLURIPOTENT STEM CELL AND METHODS OF MAKING AND USING
Document Type and Number:
WIPO Patent Application WO/2017/100403
Kind Code:
A8
Abstract:
Induced pluripotent stem cells (iPSCs) derived from a T cell of a T cell subset. T cells derived from iPSCs derived from a T cell. Methods of deriving iPSCs from a T cell. Methods of deriving T cells from iPSCs including deriving a T cell of a T cell subset from an iPSC. Methods of engineering chimeric antigen receptor (CAR)-expressing or T cell receptor (TCR)-expressing iPSC. Methods of administering T cells derived using the methods disclosed. Induced pluripotent stem cell lines derived from T cells, methods of deriving induced pluripotent stem cell lines, and methods of deriving T cells from induced pluripotent stem cell lines.
Inventors:
BLAZAR BRUCE R (US)
PATEL DHARMESHKUMAR (US)
WEBBER BEAU R (US)
TOLAR JAKUB (US)
PATEL DHARMESHKUMAR (US)
WEBBER BEAU R (US)
TOLAR JAKUB (US)
Application Number:
PCT/US2016/065524
Publication Date:
August 10, 2017
Filing Date:
December 08, 2016
Export Citation:
Assignee:
UNIV MINNESOTA (US)
BLAZAR BRUCE R (US)
PATEL DHARMESHKUMAR (US)
WEBBER BEAU R (US)
TOLAR JAKUB (US)
BLAZAR BRUCE R (US)
PATEL DHARMESHKUMAR (US)
WEBBER BEAU R (US)
TOLAR JAKUB (US)
International Classes:
C12N5/0783; C12N5/074
Attorney, Agent or Firm:
ARNESON, Laura, N. (US)
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