Title:
HUMANIZED ANTI-BASIGIN ANTIBODIES AND THE USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/186182
Kind Code:
A1
Abstract:
Provided herein is a humanized anti-BASIGIN antibody or antigen binding fragment thereof, which comprises heavy chain variable region(V H) comprising an amino acid sequence of SEQ ID NO:1, optionally further comprises light chain variable region (V L) comprising an amino acid sequence of SEQ ID NO: 2. Also provided a composition comprising the humanized anti-BASIGIN antibody or antigen binding fragment thereof, an isolated nucleic acid sequence encoding the humanized anti-BASIGIN antibody or antigen binding fragment thereof, a vector comprising the nucleic acid, a host cell comprising the vector, and use of the humanized anti-BASIGIN antibody or antigen binding fragment thereof.
Inventors:
CHEN ZHINAN (CN)
ZHU PING (CN)
HUANG WAN (CN)
ZHANG ZHENG (CN)
ZHANG YANG (CN)
ZHANG MENGYAO (CN)
BIAN HUIJIE (CN)
JIANG JIANLI (CN)
ZHU PING (CN)
HUANG WAN (CN)
ZHANG ZHENG (CN)
ZHANG YANG (CN)
ZHANG MENGYAO (CN)
BIAN HUIJIE (CN)
JIANG JIANLI (CN)
Application Number:
PCT/CN2017/082713
Publication Date:
November 02, 2017
Filing Date:
May 02, 2017
Export Citation:
Assignee:
FOURTH MILITARY MEDICAL UNIV (CN)
International Classes:
C07K16/42; A61K39/395; A61P33/06; A61P35/00
Foreign References:
| CN105820250A | 2016-08-03 | |||
| CN104086654A | 2014-10-08 | |||
| CN101550416A | 2009-10-07 |
Other References:
YANG, B.: "Molecular Modeling and Docking of HAbl8G/ CD 147 with Its Monoclonal Antibody and Antibody Humanization Design", MASTER THESIS, 15 April 2008 (2008-04-15), pages 1 - 83, XP009515631
ZHU HONGBIN: "Preparation of anti-HAbl8G/ CD 147 antibody fragment (HAbl8-huScFv)2-Fc and characterization of in vitro anti-tumor effec t", MASTER THESIS, 15 December 2009 (2009-12-15), pages 1 - 87, XP009515633
YE, H.: "Preparation and functional characterization of anti-human monoclonal antibody against recombinant extracellular domain of HAb18G/ CD 147", DOCTORAL MASTER THESIS, 15 October 2005 (2005-10-15), pages 1 - 110, XP009515634
ZHU HONGBIN: "Preparation of anti-HAbl8G/ CD 147 antibody fragment (HAbl8-huScFv)2-Fc and characterization of in vitro anti-tumor effec t", MASTER THESIS, 15 December 2009 (2009-12-15), pages 1 - 87, XP009515633
YE, H.: "Preparation and functional characterization of anti-human monoclonal antibody against recombinant extracellular domain of HAb18G/ CD 147", DOCTORAL MASTER THESIS, 15 October 2005 (2005-10-15), pages 1 - 110, XP009515634
Attorney, Agent or Firm:
JUN HE LAW OFFICES (CN)
Download PDF:
Previous Patent: NETWORK ACCESS CONTROL
Next Patent: APPARATUS FOR MEASURING BLOOD COAGULATION DATA, AND USE METHOD AND CALIBRATION METHOD THEREOF
Next Patent: APPARATUS FOR MEASURING BLOOD COAGULATION DATA, AND USE METHOD AND CALIBRATION METHOD THEREOF