Title:
HUMANIZED ANTI-CCR2 ANTIBODIES AND METHODS OF USE
Document Type and Number:
WIPO Patent Application WO2005060368
Kind Code:
A3
Abstract:
The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the interaction of a cell bearing mammalian CCR2 with a ligand thereof, and to use of the antibodies and fragments in therapeutic, prophylactic and diagnostic methods.
Inventors:
O'KEEFE THERESA (US)
PONATH PAUL (US)
PONATH PAUL (US)
Application Number:
PCT/US2003/039599
Publication Date:
December 22, 2005
Filing Date:
December 10, 2003
Export Citation:
Assignee:
MILLENNIUM PHARM INC (US)
O'KEEFE THERESA (US)
PONATH PAUL (US)
O'KEEFE THERESA (US)
PONATH PAUL (US)
International Classes:
A61K39/395; C07K16/28; (IPC1-7): A61K39/395
Foreign References:
| US20020042370A1 | 2002-04-11 |
Other References:
See also references of EP 1631311A4
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