Title:
HYDRATED PYRIDO(4,3-B)INDOLE-BASED PHARMACEUTICAL COMPOSITION FOR TREATING NEURODEGENERATIVE DISEASES, METHOD FOR PRODUCING SAME AND PHARMACEUTICAL AGENT BASED THEREON
Document Type and Number:
WIPO Patent Application WO/2011/084086
Kind Code:
A3
Abstract:
The invention relates to the field of medicine. The pharmaceutical composition for treating neurodegenerative diseases comprises hydrated pyrido(4,3-b)indole and a polymer component selected from the group comprising: blood serum albumin, sodium alginate, amylopectin, hydroxyethyl starch, dextran, gelatin, sodium caseinate, carboxymethyl cellulose, carrageenan, starch, phosphorylated starch, lactalbumin, methyl cellulose, ovalbumin, pectin, polyvinylpyrrolidone, sodium polygalacturonate, a copolymer of lactic and glycolic acids, cyclodextrin, (2-hydroxypropyl)cyclodextrin or mixtures thereof. The components make up the composition in the following proportions (parts by weight): hydrated pyrido(4,3-b)indole: 10-60; polymer component: 40-90. The method for preparing the pharmaceutical composition consists in diluting the components of the composition in a common solvent, maintaining the same at a temperature of from -40 to +50° C for 0.5 to 8 hours, and drying. The agent for treating neurodegenerative diseases comprises an effective amount of the pharmaceutical composition and a pharmaceutically acceptable filler.
Inventors:
IVANOV ROMAN VICTOROVICH (RU)
LOZINSKIY VLADIMIR IOSIFOVICH (RU)
BALAKIN KONSTANTIN VALERYEVICH (RU)
BACHURIN SERGEY OLEGOVICH (RU)
LOZINSKIY VLADIMIR IOSIFOVICH (RU)
BALAKIN KONSTANTIN VALERYEVICH (RU)
BACHURIN SERGEY OLEGOVICH (RU)
Application Number:
PCT/RU2010/000768
Publication Date:
September 22, 2011
Filing Date:
December 21, 2010
Export Citation:
Assignee:
UCHREZHDENIE ROSSIISKOI AKADEMII NAUK INST FIZIOL AKTIVNIKH VESHCHESTV RAN IFAV RAN (RU)
IVANOV ROMAN VICTOROVICH (RU)
LOZINSKIY VLADIMIR IOSIFOVICH (RU)
BALAKIN KONSTANTIN VALERYEVICH (RU)
BACHURIN SERGEY OLEGOVICH (RU)
IVANOV ROMAN VICTOROVICH (RU)
LOZINSKIY VLADIMIR IOSIFOVICH (RU)
BALAKIN KONSTANTIN VALERYEVICH (RU)
BACHURIN SERGEY OLEGOVICH (RU)
International Classes:
A61K31/4427; A61K31/404; A61K31/407; A61P25/00
Foreign References:
| RU2334514C1 | 2008-09-27 | |||
| RU2106864C1 | 1998-03-20 | |||
| RU2338533C1 | 2008-11-20 | |||
| US6187785B1 | 2001-02-13 |
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