Title:
HYDRAZIDE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/032715
Kind Code:
A1
Abstract:
Disclosed is a compound having a structure represented by formula (I). The compound has excellent antiviral activity against orthopoxvirus, has multiple advantages compared with a marketed drug Tecovirimat, and has important development significance and use prospects. Further provided are a preparation method for the compound represented by formula (I) and a use of the compound in the treatment of related diseases caused by orthopoxvirus related viruses such as smallpox virus, monkeypox virus, cowpox virus, camelpox virus, and horsepox virus.
Inventors:
WANG WEI (CN)
SUN XIAOYANG (CN)
ZENG HONG (CN)
GONG XIAOMING (CN)
WANG YING (CN)
LI SENLIN (CN)
PAN DESI (CN)
LU XIANPING (CN)
SUN XIAOYANG (CN)
ZENG HONG (CN)
GONG XIAOMING (CN)
WANG YING (CN)
LI SENLIN (CN)
PAN DESI (CN)
LU XIANPING (CN)
Application Number:
PCT/CN2023/112217
Publication Date:
February 15, 2024
Filing Date:
August 10, 2023
Export Citation:
Assignee:
SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN)
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD (CN)
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD (CN)
International Classes:
A61K31/403; C07D209/70; A61P31/20; C07D403/12; C07D405/12; C07D413/12
Domestic Patent References:
| WO2004112718A2 | 2004-12-29 |
Foreign References:
| CN101702904A | 2010-05-05 | |||
| CN116730995A | 2023-09-12 | |||
| CN101775007A | 2010-07-14 |
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