Title:
HYDROCHLORIDES OF VANCOMYCIN ANTIBIOTICS AND PROCESS FOR PRODUCING THE SAME
Document Type and Number:
WIPO Patent Application WO/1999/017793
Kind Code:
A1
Abstract:
Hydrochlorides of vancomycin antibiotics prepared by firstly freezing an aqueous solution of a vancomycin antibiotic hydrochloride at - 1 to - 20 °C, then secondarily freezing the same at - 25 to - 80 °C, and vacuum-drying the resultant frozen solid matter.
Inventors:
SAWAI SEIJI (JP)
NISHIWAKI KENJI (JP)
OHTOMO KAZUMI (JP)
KAGAYAMA AKIRA (JP)
NISHIWAKI KENJI (JP)
OHTOMO KAZUMI (JP)
KAGAYAMA AKIRA (JP)
Application Number:
PCT/JP1998/004098
Publication Date:
April 15, 1999
Filing Date:
September 11, 1998
Export Citation:
Assignee:
FUJISAWA PHARMACEUTICAL CO (JP)
SAWAI SEIJI (JP)
NISHIWAKI KENJI (JP)
OHTOMO KAZUMI (JP)
KAGAYAMA AKIRA (JP)
SAWAI SEIJI (JP)
NISHIWAKI KENJI (JP)
OHTOMO KAZUMI (JP)
KAGAYAMA AKIRA (JP)
International Classes:
A61K38/14; C07K9/00; A61K38/00; (IPC1-7): A61K38/16; C07K9/00; C07K1/14
Domestic Patent References:
| WO1997019690A1 | 1997-06-05 |
Foreign References:
| JPH01146825A | 1989-06-08 | |||
| JPS6310718A | 1988-01-18 | |||
| JPH0673085A | 1994-03-15 | |||
| JPH06345663A | 1994-12-20 |
Other References:
SCHMIDT D. J., AKERS M. J.: "CRYOGRANULATION: A POTENTIAL NEW FINAL PROCESS FOR BULK DRUG SUBSTANCES.", BIOPHARM, CLEVELAND,OH, US, 1 April 1997 (1997-04-01), US, pages 28 + 30 + 32., XP002914615
See also references of EP 1025852A4
See also references of EP 1025852A4
Attorney, Agent or Firm:
Seki, Hideo (Ltd. Osaka Factory 1-6 Kashima 2-chome Yodogawa-ku, Osaka-shi Osaka, JP)
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